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Acarbose

Acarbose is a complex oligosaccharide that competitively inhibits the ability of brush-border alpha-glucosidase enzymes to break down ingested carbohydrates into absorbable monosaccharides, reducing carbohydrate absorption and subsequent postprandial insulin levels.

Other names for this medication:
Abacus, Acarb, Acarbose, Acarex, Acarwin, Acraz, Asucrose, Diabose, Discarb, Disorb, Exforge, Glubose, Glucar, Glucarb, Glucobay, Glucobose, Gludase, Hebose, Olcarbos, Prandase, Rebose, Recarb, Subase, Zebay, Zebose

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Description

Generic Acarbose is used for treating type 2 diabetes in adults whose diabetes cannot be managed with diet alone. Generic Acarbose may be used alone, in combination with other oral diabetes medicines, or with insulin. Generic Acarbose is a glucosidase inhibitor. It works by slowing down the enzyme that turns carbohydrates into glucose; it decreases blood sugar levels following a meal. Acarbose is also known as Acarbose, Glucobay, Glucor, Rebose. Generic name of Generic Acarbose is Acarbose. Brand name of Generic Acarbose is Acarbose.

Dosage

Follow all directions on your prescription label. Do not take this medicine in larger or smaller amounts or for longer than recommended.

Take Acarbose with the first bite of a main meal, unless your doctor tells you otherwise.

Your blood sugar will need to be checked often, and you may need other blood tests at your doctor's office.

If you take Acarbose with insulin or other diabetes medications, your blood sugar could get too low.

Low blood sugar (hypoglycemia) can happen to everyone who has diabetes. Symptoms include headache, hunger, sweating, confusion, irritability, dizziness, or feeling shaky. Always keep a source of dextrose (D-glucose) with you in case you have low blood sugar. When taking Acarbose, dextrose will work better than cane sugar or table sugar in treating hypoglycemia. Sources of dextrose include honey, dates, raisins, plums, dried prunes, grapes, or glucose tablets. Be sure your family and close friends know how to help you in an emergency.

If you have severe hypoglycemia and cannot eat or drink, use a glucagon injection. Your doctor can prescribe a glucagon emergency injection kit and tell you how to use it.

Also watch for signs of high blood sugar (hyperglycemia) such as increased thirst, increased urination, hunger, dry mouth, fruity breath odor, drowsiness, dry skin, blurred vision, and weight loss.

Check your blood sugar carefully during times of stress, travel, illness, surgery or medical emergency, vigorous exercise, or if you drink alcohol or skip meals. These things can affect your glucose levels and your dose needs may also change. Do not change your medication dose or schedule without your doctor's advice.

Acarbose is only part of a complete treatment program that may also include diet, exercise, weight control, regular blood sugar testing, and special medical care. Follow your doctor's instructions very closely.

Store at room temperature away from moisture and heat. Keep the bottle tightly closed when not in use.

Detailed Acarbose dosage information

Overdose

If you overdose Generic Acarbose and you don't feel good you should visit your doctor or health care provider immediately.

Storage

Store at room temperature below 25 degrees C (77 degrees F) away from moisture and heat. Keep container tightly closed. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Acarbose are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

You should not use Acarbose if you are allergic to it, or if you have:

inflammatory bowel disease; a blockage in your intestines; a digestive disorder affecting your intestines; intestinal ulcer (of your colon); cirrhosis of the liver; or diabetic ketoacidosis (call your doctor for treatment with insulin).

To make sure Acarbose is safe for you, tell your doctor if you have:

liver disease; kidney disease; a bowel or intestinal disorder; or a stomach disorder.

Acarbose is not expected to harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.

It is not known whether acarbose passes into breast milk or if it could harm a nursing baby. You should not breast-feed while you are using acarbose.

Acarbose is not approved for use by anyone younger than 18 years old.

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Activation of nestin-positive duct stem (NPDS) cells in pancreas upon neogenic motivation and possible cytodifferentiation into insulin-secreting cells from NPDS cells. For the purposes of description, the subsequent events may be grouped in three cascades characterized by the key proteins involved. Taken together, I suggest that SBP may be involved in the initial sequential events in rapid cell outgrowth, such as determining direction of cell outgrowth and recruitment of actin monomer. However, with careful management of complications, the therapy may have a considerable efficacy in some patients with cirrhosis and HCV infection. The CT colonography data sets were analyzed by virtual colon dissection, which virtually bisects and unfolds the colon along its longitudinal axis to inspect the inner colonic surface for polyps. To determine associations of serum OPG and RANKL concentrations with HIV infection and subclinical atherosclerosis.

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