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Adipine (Nifedipine)

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Adipine is a drug that performs by relaxing the muscles inside the heart and blood vessels in order to enable easier blood flow. This enables the heart to have an easier time pumping blood. The active ingredient is nifedipine and it a part of a class of drugs called calcium channel blockers. The primary use of this medication is to help stop chest pain (angina) and help treat high blood pressure problems (hypertension). In addition to this it can also be used in order to heighten the supply of oxygen and blood to the heart and help with a specific blood circulation condition called Raynaud’s phenomenon.

Other names for this medication:
Adalate, Amarkor, Anpect, Antrolin, Aprical, Calcheck, Calcibloc, Cardiosol, Coral, Cordaflex, Corinfar, Depine, Duranifin, Fenidina, Glopir, Hypan, Lemar, Myogard, Nedipin, Nicardia, Nidicard, Nifecap, Nifecardia, Nifecor, Nifedip, Nifedipino, Nifedipinum, Nifelat, Nifelong, Nifical, Nycopin, Sepamit, Sidalat, Tenif, Tensomax, Tredalat, Vasdalat, Zenusin

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Also known as: Nifedipine


Nifedipine is used alone or together with other medicines to treat severe chest pain (angina) or high blood pressure (hypertension). High blood pressure adds to the workload of the heart and arteries. If it continues for a long time, the heart and arteries may not function properly. This can damage the blood vessels of the brain, heart, and kidneys, resulting in a stroke, heart failure, or kidney failure. High blood pressure may also increase the risk of heart attacks. These problems may be less likely to occur if blood pressure is controlled.

Nifedipine is a calcium channel blocker. It works by affecting the movement of calcium into the cells of the heart and blood vessels. As a result, nifedipine relaxes blood vessels and increases the supply of blood and oxygen to the heart while reducing its workload.

This medicine is available only with your doctor's prescription.


This section provides information on the proper use of a number of products that contain nifedipine. It may not be specific to Adipine OROS. Please read with care.

In addition to the use of this medicine, treatment for your high blood pressure may include weight control and changes in the types of foods you eat, especially foods high in sodium (salt). Your doctor will tell you which of these are most important for you. You should check with your doctor before changing your diet.

Many patients who have high blood pressure will not notice any signs of the problem. In fact, many may feel normal. It is very important that you take your medicine exactly as directed and that you keep your appointments with your doctor even if you feel well.

Remember that this medicine will not cure your high blood pressure, but it does help control it. You must continue to take it as directed if you expect to lower your blood pressure and keep it down. You may have to take high blood pressure medicine for the rest of your life. If high blood pressure is not treated, it can cause serious problems such as heart failure, blood vessel disease, stroke, or kidney disease.

Swallow the extended release tablet whole. Do not break, crush, or chew it. It is best to take this tablet on an empty stomach.

If you are taking the extended-release tablets, part of the tablet may pass into your stool after your body has absorbed the medicine. This is normal and nothing to worry about.

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For treatment of chest pain or high blood pressure: For oral dosage form (capsules): Adults—At first, 10 milligrams (mg) three times a day. Your doctor may increase your dose as needed. Children—Use and dose must be determined by your doctor. For oral dosage form (extended-release tablets): Adults—At first, 30 or 60 milligrams (mg) once a day. Your doctor may increase your dose as needed. However, the dose is usually not more than 90 mg once a day. Children—Use and dose must be determined by your doctor.


If you overdose Adipine and you don't feel good you should visit your doctor or health care provider immediately.


Store at room temperature between 15 and 25 degrees C (59 and 77 degrees F) away from moisture and heat. Keep container tightly closed. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Adipine are:

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Culture, behavior and multiplication of various brain virus strains in tissue culture. Clinical and laboratory efficiency of rapid screening urine cultures by nephelometry. To evaluate the effectiveness of neuromuscular training in reducing the rate of acute knee injury in adolescent female football players. With the demonstration that DNA vaccines protect against foot-and-mouth disease in sheep and pigs, and the advantages these DNA vaccines have over the conventional formulations, this approach may provide a better solution to the control of this disease. The simulated timolol concentration in the aqueous humor was about 1.8 times higher than the previously published experimental values. Relative effects of haloforms and epinephrine on cardiac automaticity. Each year, in France, the number of cardiac arrests is evaluated between 30,000 to 50,000. Stickleback with structural plate asymmetries had fewer trout-induced scars than symmetric fish in the significant majority of populations, and there was a decrease in structural plate asymmetry with age in stained-water habitats, suggesting that trout predators may be selectively removing asymmetric fish in some lakes. The nanoscale movement was studied with scanning transmission electron microscopy (STEM) using a liquid enclosure consisting of microchips with silicon nitride windows. The effect of ionizing rays on the ultrastructure of collagen fibrins.

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The strains were isolated using Madin- Darby canine kidney (MDCK) cells, and genetically characterized by phylogenetic analysis for genetic diversity. Insights into the thermoelectric properties of SnSe from ab initio calculations. The level and course of attention was measured hourly in 9 drug intoxicated patients after a suicide attempt over periods which varied between 12 and 72 hrs. Template-Based Orbital Wall Fracture Treatment Using Statistical Shape Analysis. No marked changes in thymus or spleen weight were observed after THI treatment, although there was an increased number of pyknotic cells in the thymic cortex, mainly engulfed by macrophages and there appeared to be a slight thinning of the cortex area. Ruminococcus (decreased by SCF) showed negative correlation with high-density lipoprotein cholesterol and fasting blood glucose. The trion formation facilitates electrical control of exciton transport in transition metal dichalcogenide heterostructures, which can be utilized in various optoelectronic applications.

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The objective of this study was to evaluate and compare biochemical failure free survival (BFFS) after low-dose-rate brachytherapy (LDRB) alone for patients with prostate cancer using ASTRO and Phoenix criteria, and detect prognostic factors. Only phenyl-based polymers are nonplanar, but the main contributor to the larger band gap is electronic, not structural effects. Superficial venous incompetence: low-cost outpatient minisurgery, sclerotherapy and combined procedure as a management plan. Mud (Apr lac) mutants which have the lac genes fused to the regulatory region of exuT, uxaC, uxaA and uxaB genes were constructed. The patients could perform their daily activities very well and showed pronounced improvement in their self-confidence, self-reliance, and quality of life. How much Reliable Is Alvarado Scoring System in Reducing Negative Appendectomy?.

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The Experiences of Parents of Pediatric Patients With Acute Lymphoblastic Leukemia, 2 Months After Completion of Treatment. Conditioned facilitation of brain reward function after repeated cocaine administration. The development of fear of falling among community-living older women: predisposing factors and subsequent fall events. The aim of this study was to investigate the effect of hypoxia on the level of microRNA-18a (miR-18a) and hypoxia-inducible factor 1A (HIF1A) expressed by choroidal endothelial cells through cytological analysis. SES, based on family income (salaries, interest on savings, pensions and so on), was assessed at birth and early adulthood, and three different adiposity measures (body mass index (BMI), waist circumference (WC), waist-to-hip ratio (WHR)) ascertained at follow-up. This paper introduces the concept of the pseudo-periodic Fourier transform to the RTMA with the lattice sums technique, and proposes a spectral-domain approach to the problem of periodic cylinder array with defects. In WFR blotting, both serum samples detected a heavy IgE-binding band at approximately 20 kDa, which was not inhibited with fish. Inspired by the presence of AChE on red blood cell (RBC) membranes, we explored a biomimetic nanoparticle consisting of a polymeric core surrounded by RBC membranes to serve as an anti-organophosphate agent.

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The influence of a dopamine reuptake inhibitor (methylphenidate) and a norepinephrine reuptake inhibitor (reboxetine) was assessed in 12 cyclists performing 180 min of stationary cycling within a placebo-controlled crossover design. Three hundred fifty-two recently detoxified substance abusers were used as subjects. FREEZING-POINT DEPRESSION: NEW METHOD FOR MEASURING ULTRAMICRO QUANTITIES OF FLUIDS. The number of each type of septic postoperative complication and their total did not differ between the group treated by oral antibiotics prior to operation and the group treated peroperatively with systemic antibiotic therapy. The influence of certain anticonvulsants on the oxygen consumption of the brain in vitro. We have identified a 95 kd cell surface protein, DM-GRASP, that is expressed on a restricted population of axons. Differences among materials were detected regarding the properties tested, which may imply variations in their clinical performance. Relative specificity of serologic tests for syphilis in Mycobacterium leprae infection. New tasks and prerequisites for ensuring industrial health services. No significant difference was observed in the total bacterial count between LAMPSS-positive and -negative samples.

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Histochemically, 5-hydroxytryptamine (5-HT) blockers (methyserigide and cyprohepatdine) and dopamine (DA) blockers (haloperidol and sulpiride) produced no apparent changes in fluorescence pictures after injection of L-5HTP. The Nasal Obstruction Symptom Evaluation (NOSE) scale is a symptom-specific, self-completed questionnaire for assessing quality of life related to nasal obstruction or its treatment in patients with septal deviation. Even if ovulation occurs occasionally, the changes which occur secondary to chronic exposure to the progestin portion of OCs make both fertilization and implantation unlikely. Primary pyomyositis is a common health problem in Northern Uganda. Furthermore, the Ia specificities of each I-region sublocus (I-1A, I-1B, I-C) seem to be associated with FrR, since FcR function was also inhibited when the blocking anti-Ia antiserum recognized only restricted Ia specificities. Metal and metalloid foliar uptake by various vegetable species, exhibiting different morphologies, use (food or fodder) and life-cycle (lettuce, parsley and rye-grass) were studied.

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We analyzed autopsy reports of newborns (under 28 days old), stillborns and miscarried fetuses in 1991 and 2001. Fragmentation behavior and synthesis of bicyclic and monocyclic models of the 20-ketosteroids. A project on patient waiting times at appointment in an orthodontic department. Further studies are needed to evaluate whether or not treatment to prevent sodium retention is useful for patients who exhibit increased PT-AGT in renal biopsies. Localized BP is rare and norvasc medication card has been previously described in association with other cutaneous disorders. This assay allows the simultaneous qualitative demonstration of antigenicity and immunogenicity of antigens obtained as synthetic peptides, recombinant molecules, or crude preparations, with high sensitivity and specificity. Eligible for the study were women consecutively observed at the participating centers. Therefore, technology and language barriers may have influenced the results. The effect of a nonsteroidal antiandrogenic compound and its biologically active metabolite (SCH-16423) on these parameters was also evaluated. Hence, high-frequency TENS treatment significantly reduced pain intensity immediately after its use and 60 min later.

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Alpha-Fetoprotein and early histological changes of hepatic tissue in DAB-hepatocarcinogenesis. A micro-method for the photometric determination of calcium in serum with ammonium purpurate. Evaluation of Society of Gynecologic Oncologists (SGO) ovarian cancer quality surgical measures. Development of a novel frontal bone defect mouse model for evaluation of osteogenesis efficiency. MR imaging of acute pancreatitis: correlation of abdominal wall edema with severity scores. An adapted theoretical framework, presented here, has potential application in future implementation studies. Endocytobionts in Dermacentor reticulatus ticks (Ixodidae): an electron microscope study. Hence, we explored the behaviour of another important aspect which is the immune properties in long-term cultured cells. The hypometabolic pattern of each individual and comparisons across the groups of subjects (control subjects, sCJD and FFI) were evaluated using a voxel-based analysis. Independent effects of cyclosporine and prednisone on posttransplant hypercholesterolemia.

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Diuresis appears earlier in pregnant females indicating a more rapid inactivation of vasopressin. The use of the drainage technic in the conservative treatment of middle ear inflammation in infancy and childhood. Comparison of the NA sequences of a panel of H3N2 viruses with differing sensitivities to the salivary inhibitor revealed that surface residues 368 to 370 (N2 numbering) outside the active site played a is diflucan an antibiotic key role in resistance. The effects of acetylcholine (ACh) on the cell volume of the isolated rat mandibular acini were studied stereologically using video-enhanced contrast optical microscopy. Contemporary in vitro synergy rates for aztreonam combined with newer fluoroquinolones and beta-lactams tested against gram-negative bacilli. Overall, we conclude that the weight of evidence supports a causal role of PCBs in lymphomagenesis. Changes in underlying causes of death during 85 years of autopsy practice in Trieste. Of practical significance, was an improvement in measures for both groups with a greater improvement in awareness of present moment experience for the intervention group. Preventive antidepressants may have a role in high-risk cases, especially for those with recurrent depression.

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On nights 2 and 3, sleep was fragmented using auditory stimuli that were delivered with increasing intensity until an arousal was noted. A total of 9483 colonoscopies performed after positive testing in a colorectal cancer screening programme setting were included. The exudative myopathy in swine and its determination by meat inspection. Certain differences in the antigenic properties of viruses isolated in Africa and in Czechoslovakia were found. Here, we used finite element analysis (FEA) to investigate the biomechanical implications of these three morphologies, in a squirrel, guinea pig and rat. Previously, it was shown that intensity of mouse intermale aggression was positively associated with activity of the key enzyme of 5-HT synthesis - tryptophan hydroxylase 2 (TPH2) in mouse brain. Lost in distractors: Reduced Autobiographical Memory Specificity and dispersed activation spreading over distractors in working memory. Storage of histamine in the blood following liberation from liver and antrum through trypsin: protective mechanism or a factor promoting pancreatic shock.

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Avoiding and treating perioperative complications of distal radius fractures. A study of a different dose-intense infusion schedule of phenylacetate in patients with recurrent primary brain tumors consortium report. We tested the changes in motor threshold, MEP size and CSP duration evoked by focal rTMS in 23 patients with neuropathic pain before and after a 1-week course of treatment with carbamazepine, gabapentin, topiramate and placebo. Nonalcoholic fatty liver disease (NAFLD) is associated with increased cardiovascular and liver-related mortality. Prevention in general practice: the views of doctors in the Oxford region.

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THE EFFECT OF THE CAROTID SINUS PRESSOR REFLEX ON RENAL FUNCTION AND ELECTROLYTE EXCRETION. Thus far spindle frequency patterns in patients with sleep disorders have not been studied. Inhaled what is the side effect of norvasc 10 mg corticosteroids (ICS) are a significant part of treatment. The proliferation, cell cycle and apoptosis, and messenger RNA expression of SOCS1 in MV3 and A375 cells were detected using MTT assay, flow cytometry, and quantitative real-time polymerase chain reaction, respectively. Interpretative phenomenological analysis was used for data collection and analysis. After 8 weeks, the dogs were killed, and their whole urinary system was sent for histopathologic examinations. We hypothesized that a multiphase, multifaceted quality improvement initiative would engage relevant stakeholders, address known barriers to adoption, and improve overall adherence. Then, a 2,127 bp open reading frame of a gene designated spy1 that overlaps with the above fragment was identified and its structure and biological functions were investigated. The bacterial cell and the protein edestin as carriers for R oligosaccharide determinants. Each patient had received non-steroidal anti-inflammatory drugs (NSAIDs) in the immediate postoperative period.

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On-Chip Evaluation of DNA Methylation with Electrochemical Combined Bisulfite Restriction Analysis Utilizing a Carbon Film Containing a Nanocrystalline Structure. The condition appears to be controlled by a ventolin hfa generic or equal affordable drug recessive allele at a single autosomal locus. The burden of reviewing long-term scalp electroencephalography (EEG) is not much alleviated by automated spike detection if thousands of events need to be inspected and mentally classified by the reviewer. In that there is only one case reported occuring in the lower one third of face. There was a marked difference in the inhibition of fordine on pseudo ChE of different species.

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Emergency department cancer unit and management of oncologic emergencies: experience in Asan Medical Center. Why do some T cell receptor cytoplasmic domains associate with the plasma membrane?. Loss of PRRX1 induces epithelial-mesenchymal transition and cancer stem cell-like properties in A549 cells. Report of Leishmania (Zoomastigophorea: Kinetoplastida) in Anolis lucius in Cuba. A clear correlation has been shown between the resistance of cats to development of lethal tumors following inoculation of feline sarcoma virus high dose allegra side effects and the presence of high humoral antibody titers to FOCMA. In addition, the object-cueing effect occurred only when the cue was spatially invalid and not when it was spatially valid.

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The aim of this review is not to cite all related articles, but highlight the steps, which in our opinion, meant important progresses in solid-state nanopore analysis. Institute of Occupational Health, Helsinki, Finland, and Second Department of Medicine, University of Helsinki. Application of Western Blotting for the Post-Treatment Monitoring of Human Cystic Echinococcosis. Health in school: an examination of the reference documents for the forty years of compulsory health programs, 1971-2011. In vitro activity and in vivo efficacy of a combination therapy of diminazene and chloroquine against murine visceral leishmaniasis. Pulmonary contusion (PC) is a leading injury in blunt chest trauma and is most commonly caused by motor vehicle crashes (MVC). PDK1-FoxO1 pathway in AgRP neurons of arcuate nucleus promotes bone formation via GHRH-GH-IGF1 axis. Nineteen patients received low-dose of cisplatin just before every delivery of radiation therapy, and 21 patients received two cycles of 5-FU-based regimen during radiotherapy. Much research to date has focused on negative social aspects in communities, such as substance abuse and high numbers of school drop-outs. The TaqMan MGB-based probe fluorescence quantitative PCR assay method was a reliable, specific, sensitive and useful tool for rapid detection of Clostridium piliforme.

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Cytochrome c and resveratrol preserve platelet function during cold storage. When the proposed algorithm was applied to the test set, the scores of 85.853 bpm2 for fetal heart rate and an error of 9.725 ms RMS for fetal RR-interval estimation were obtained. Thus, on the one hand, it was found that LPS did not function as an adjuvant in C3H/HeJ mice, a unique strain whose spleen cells were also unresponsive to LPS-induced mitogenesis. The early phase defect was observed 2-5 days and 4-12 days after tumor transplantation in rats and mice respectively. Survival and recurrence rates in breast cancer are variable for common diagnoses, and therefore the biological underpinnings of the disease that determine those outcomes are yet to be fully understood. Extension of a retracted ciliary sulcus tube of Ahmed glaucoma implant with angiocatheter segment. Comparative neurobiological and neuropsychological deficits in adolescent and adult schizophrenic and nonschizophrenic patients. (18)F-FDG PET/CT imaging plays an very important role in guiding clinical restaging, evaluating the treatment outcome, monitoring relapse and predicting prognosis of T-cell lymphoma. Extending the multifoci perspective: The role of supervisor justice and moral identity in the relationship between customer justice and customer-directed sabotage. Evaluation of a rapid bacterial ATP assay for screening BAL samples from ICU patients submitted for quantitative bacterial cultures.

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