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Alendix (Alendronate)
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Alendix

Alendix is used to treat osteoporosis caused by menopause, steroid use, or gonadal failure. Alendix is for use when you have a high risk of bone fracture due to osteoporosis. Alendix is also used to treat Paget's disease of bone.

Other names for this medication:
Alant, Alendix, Alendronate, Alenost, Bifosa, Denfos, Osteofos, Ostogee, Poronil, Ralenost, Restofos, Zophost

Similar Products:
Rulide, Zyrtec, Avelox, Dramamine, Allegra, Lopressor

Also known as: Alendronate

Description

Generic Alendix is a drug which helps to fight with postmenopausal osteoporosis, steroid-induced osteoporosis, Pagets disease of bone. Generic Alendix is a medicine which belongs to the group of medicines called bisphosphonates. Alendix is also known as Alendronic acid, Alendronate sodium, Ostofos. Generic Alendix works by preventing bone breakdown and increasing bone density (thickness). Generic name of Generic Alendix is Alendronate. Brand name of Generic Alendix is Alendix.

Dosage

Take Alendix Plus D exactly as it was prescribed for you. Follow all directions on your prescription label. Do not take this medicine in larger or smaller amounts or for longer than recommended.

Alendix Plus D tablets are taken once each week. Choose the day of the week that best fits your schedule. Every week, take one Alendix Plus D tablet on your chosen day.

Take the Alendix Plus D tablet first thing in the morning, at least 30 minutes before you eat or drink anything or take any other medicine.

Take the tablet with a full glass (6 to 8 ounces) of water. Use only plain water (not mineral water) when taking this medicine.

Do not crush, chew, or suck the tablet. Swallow the pill whole.

After taking an Alendix Plus D tablet, carefully follow these instructions:

Do not lie down or recline for at least 30 minutes after taking Alendix Plus D. Do not eat or drink anything other than plain water. Do not take any other medicines including vitamins, calcium, or antacids for at least 30 minutes after taking Alendix Plus D. It may be best to take your other medicines at a different time of the day. Talk with your doctor about the best dosing schedule for your other medicines.

To be sure this medication is helping your condition, your bone mineral density will need to be tested on a regular basis. You may not need to take Alendix Plus D for longer than 3 to 5 years if you take it for osteoporosis.

If you need to have any dental work (especially surgery), tell the dentist ahead of time that you are using Alendix Plus D. You may need to stop using the medicine for a short time.

Alendix Plus D is only part of a complete program of treatment that may also include diet changes, exercise, and taking calcium and vitamin supplements. Follow your diet, medication, and exercise routines very closely.

Store at room temperature away from moisture and heat.

Detailed Alendix Plus D dosage information

Overdose

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. Drink a full glass of milk and call your local poison control center or emergency room right away. Do not make yourself vomit and do not lie down.

Overdose symptoms may include muscle cramps, numbness or tingling, tight muscles in your face, seizure (convulsions), irritability, and unusual thoughts or behavior.

Storage

Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) away from moisture and heat. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Alendix are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

You should not take Alendix if you are allergic to alendronate, or if you have:

low levels of calcium in your blood (hypocalcemia); or problems with the muscles in your esophagus (the tube that connects your mouth and stomach).

Do not take Alendix if you cannot sit upright or stand for at least 30 minutes. Alendix can cause serious problems in the stomach or esophagus. You must stay upright for at least 30 minutes after taking this medicine.

To make sure this medicine is safe for you, tell your doctor if you have ever had:

trouble swallowing; problems with your stomach or digestion; low levels of calcium in your blood; a dental problem (you may need a dental exam before you begin taking Alendix); kidney disease; or any condition that makes it hard for your body to absorb nutrients from food (malabsorption).

In rare cases, this medicine may cause bone loss (osteonecrosis) in the jaw. Symptoms include jaw pain or numbness, red or swollen gums, loose teeth, or slow healing after dental work. The longer you use Alendix, the more likely you are to develop this condition.

Osteonecrosis of the jaw may be more likely if you have cancer or received chemotherapy, radiation, or steroids. Other risk factors include blood clotting disorders, anemia (low red blood cells), and a pre-existing dental problem.

Alendix has also been reported to cause fractures, or broken bones, in the large bones of the leg. Tell your doctor if you have any leg or groin pain while using Alendix.

Talk with your doctor about the risks and benefits of using this medication.

It is not known whether Alendix will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant. Stop using the medicine and tell your doctor right away if you become pregnant.

It is not known whether alendronate passes into breast milk or if it could harm a nursing baby. Ask your doctor about any risk.

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These results demonstrated the involvement of immune factors in the pathogenesis of dysferlinopathy. We examined the effects of baseline drug use and dependence on alcohol use outcomes following brief motivational intervention for at-risk drinking (BMI-ETOH). The findings suggest that early intervention to improve visual acuity in older people may be important. The construct and criterion validity of the PHQ-2 make it an attractive measure for depression screening. Anxiety and sedation scored on ordinal scale at time of treatment and 90 minutes later, just prior to anesthetic induction. Our results first showed that matrine reduced glucose intolerance and plasma insulin level, hepatic triglyceride content and adiposity in high-fat-fed mice without affecting caloric intake. Autopsy showed an infiltration of lymphoid cells around the cerebral ventricles and necrosis in the hypothalamo-hypophyseal system.

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The cryptic plasmid pt38 (2911 bp) of Streptococcus thermophilus ST2783, a strain isolated from Bulgarian yogurt, was subcloned and sequenced. These theoretical predictions are relevant to some recent experimental observations on the interaction of powerful ultrasonic fields with cracks. The A1298C polymorphism of the MTHFR gene is not associated with the occurrence of PCOS. Transposon disruptions within gene PA2840, which encodes a homolog of the Escherichia coli RNA-helicase DeaD, significantly reduced T3SS gene expression. Two abnormal variants commonly present in Europeans cause a deficiency that predisposes them to a progressive loss of lung elasticity. Quantitative implications of the approximate irrelevance of mammalian body size and lifespan to lifelong cancer risk. VA (ventricular arrhythmia) bursts after recanalization of the culprit vessel have been found to be related to larger infarct size (IS), using SPECT. She presented additional symptoms, that are considered typical for a HELLP syndrome, complicated by a ruptured haematoma of the liver: severe right upper-quadrant pain, decrease of haemoglobin content, enlarged liver with structural irregularities and free fluid in the abdominal cavity as examined by sonography.

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We herein showed enhancing effects of a soluble resistant maltodextrin (RM) on glucose homeostasis in mouse metabolic disease models. The in vitro antimicrobial activity of Cymbopogon essential oil (lemon grass) and its interaction with silver ions. Other factors, possibly genetic (although not HL-A-linked), environmental, or the two together, may be required for multiple sclerosis to become clinically apparent. Ele inhibits HLE-B3 proliferation, making it an attractive potential agent in regimens to treat after-cataracts. To evaluate the effectiveness of noninvasive ventilation in patients with acute hypoxemic nonhypercapnic respiratory failure unrelated to exacerbation of chronic obstructive pulmonary disease and cardiogenic pulmonary edema.

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The identification of new mechanisms of thyroid injury is essential for the development of countermeasures, both on the ground and in space, against thyroid cancer. Living-donor liver transplants are an efficient and successful treatment for acute liver failure patients. General assessment and support of the adult respiratory distress syndrome. The aim of the study reported here was to develop multifunctional, dual-ligand, modified, self-assembled nanoparticles (NPs) for the combination delivery of baicalein (BCL) and paclitaxel (PTX) prodrugs. We found differential and season-dependent risks for different types of solid fuels and kerosene as well as cooking location on child ALRI. The expression of minichromosome maintenance-3 (MCM3) proteins and their diagnostic value in oral mucosal dysplasia and squamous cell carcinoma (SCC) is not well known. Sensitivity of various strains of bacteria to the action of phagocytes. Psychometric Properties of the Spanish Version of the Sexual Inhibition/Sexual Excitation Scales for Men. Diagnosis and treatment of embolism of the superior mesenteric artery. Muscular and coordinative insufficiency caused by arthritis can lead to the observed increased hindfoot eversion from static to dynamic condition.

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Human blood monocytes: characterization of negatively selected human monocytes and their suspension cell culture derivatives. We aimed to determine upright heart rate and blood pressure (BP) changes to suggest diagnostic criteria for postural orthostatic tachycardia syndrome (POTS) and orthostatic hypertension (OHT) in Chinese children. The interobserver agreement on the histopathologic diagnosis of NRH was poor, even when assessed by well-experienced liver pathologists. This research permitted the definition during pregnancy of the normal concentrations for these four proteins and allowed us to learn more about protein exchanges between fetal blood, maternal blood and amniotic fluid. Upper GI endoscopy was performed on 49 patients treated with inhaled fluticasone propionate to examine the prevalence of esophageal candidiasis. Most of the pedicles of the lower lumbar spine and T12 are large enough to house the smallest commercially available screw.

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Nevertheless, these data only arise from prospective and retrospective cohort studies, as up to date only one very small randomized clinical trial has been completed. Advances such as open source hardware, personal medical devices, and mobile phone apps are creating opportunities for custom-made medical devices and personalized care. To assess the capability of these complexes to obstruct the pulmonary circulation, an in vitro experimental model was developed. Live imaging of migrating macrophages in vivo revealed that this mutation restricted the localization of fascin to the distal ends of filopodia. Yet, it appears that it also has the potential to increase them.

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Previous studies of pigmentation have focused on a number of genes that may play important roles in coat color regulation. PI were lower in the first group, with statistical signification in four of the six arteries. Peculiarities of the clinical picture, diagnosis and therapy of kidney calculi in children. Broberg and Morrey score, The American Shoulder and Elbow Surgeons-Elbow score, visual analogue scale, and grip and pinch strength were evaluated. We propose that tj is a critical modulator of the adhesive properties of somatic cells, facilitating germline-soma interactions that are essential for germ cell differentiation. Diagnostic approaches to support physical findings were discussed, and methods of radiological assessment provided assistance to the audience in making appropriate diagnosis in relation to hand injuries. ARE was more effective in increasing the FFM of arms, trunk and whole body and decreasing PF of trunk in men and superior on reducing FM of legs in women when comparing with AE.

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Numerical simulation of electrical impedance spectroscopy shows good agreement with the experimental measurement of DI water and PBS solution. Our data indicate that functional senescence and age-dependent mortality are influenced by beta integrins in Drosophila. Calcar resorption beneath a well-fitting flanged femoral prosthesis. The prospective significance of electronic data processing for public health care in the German Democratic Republic. We conducted an analysis of 161 consecutive patients who underwent isolated CABG surgery in a tertiary center during the period 2002-2003.

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These tools are applied to a collection of images of women where one breast has been reconstructed after mastectomy and where interest lies in shape differences between the reconstructed and unreconstructed breasts. This paper describes amino acid sequence and peptide map analyses of invertase polypeptides. Research on the interaction of hydrogen-bond acidic polymer sensitive sensor materials with chemical warfare agents simulants by inverse gas chromatography. Furthermore, the cerebral hemodynamic consequences post-DC have been researched only recently. Although it is a benign lesion, the aggressive variant raises concerns due to its huge local destructive potential and tendency to relapse. In combination with information on realistic exposure levels, in vitro studies on phagocytes may provide useful information on the health risks of NPs. Additional resistance to internal rotation afforded by a third screw placed anteriorly may offer some advantage in patients at risk for nonunion. Herein we review the current challenges and future directions of CF-LVAD therapy and sensor technology focusing on the development of a physiologic, long-term active flow adjustment strategy for CF-LVADs. The sex determination master switch, Sex-lethal (Sxl), controls sexual development as a splicing and translational regulator. Since one of the main challenges in treating acute burn injuries is preventing infection, early excising of the eschar and covering of the wound becomes critical.

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Juxta-neoplastic disc narrowing accompanying malignant disease of the vertebra. Paroxysmal cold hemoglobinuria due to an IgA Donath-Landsteiner antibody. Although the molecular mechanisms of the pathogenesis of CRC remain unclear, the inactivation of tumor suppressor genes (TSGs) through promoter methylation serves an important role. The percentage of abnormalities was found to increase with the increase in the concentration of the extract from 20 to 60 mg/ml. EFFECT OF ADULT BLOOD PRESSURES ON THE FETAL VESSELS OF THE TRANSPLANTED DOG KIDNEY. In this study, we present several demonstrations of color averaging between luminance boundaries. Clinical significance of insulin-like growth factor gene polymorphisms with survival in patients with gastrointestinal stromal tumors. LIMITATION OF OCULAR MOTILITY UNDER ACCELERATION AN OBJECTIVE ENDPOINT FOR USE WITH HUMAN CENTRIFUGE SUBJECTS.

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Safety and effectiveness of probucol as a cholesterol lowering agent. Obstetric violence involves a violation of reproductive rights of women during pregnancy, childbirth and postpartum. pBR322 and pBR313 are not transcribed by the purified RNA polymerase II when not bearing eukaryotic inserts. Lactobacillus acidophilus was examined for its capability to influence the innate immune response of HT29 intestinal epithelial cells towards SesE. Structure and function of AChBP, homologue of the ligand-binding domain of the nicotinic acetylcholine receptor. Univariate and multivariate analyses were performed using a Cox proportional hazards model to identify risk factors. Enhanced pulmonary toxicity with bleomycin and radiotherapy in oat cell lung cancer.

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Effects of tolbutamide on the diabetes of acromegaly and on the blood sugar in patients with altered endocrine states. Bioethics Symposium: The ethical food movement: What does it mean for the role of science and scientists in current debates about animal agriculture?. Results suggest a home exercise programme can be effective in reducing symptoms and improving function in construction workers with shoulder pain. The fluctuations in glucose production were synchronous with fluctuations in the concentration of plasma insulin and glucagon. Primary outcome was incident AMI rates by HCV status in each lipid strata using National Cholesterol Program guidelines for lipid strata. We propose an approach to distribute smoking-attributable expenditures by age, gender, and cigarette smoking status to reflect the known risks of smoking. All three patients were not known to have syphilis prior to presentation but have positive history of sexual promiscuity. We build on the association between the log-rank test and the univariate or stratified Cox model and show the analogy in the relative survival setting.

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Enhanced Kinetics of Electrochemical Hydrogen Uptake and Release by Palladium Powders Modified by Electrochemical Atomic Layer Deposition. Given the urgency of clinical demand for treatment of MDR bacterial sepsis, we outline directions for further work, including the need for future clinical trials in this at-risk population. An unexpected and significantly lower hydrogen-bond-donating capacity of fluorohydrins compared to nonfluorinated alcohols. In contrast, the Gal alpha 1-4 Gal beta-recognizing or mannose-binding transformants were eliminated within 48 h. The conversion of phenylpropanedinitrile dulcolax laxative tablets dosage (phenylmalononitrile) into the carbanion, followed by IR spectra, ab initio and DFT force field calculations.

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Repopulation of LCFU was rapid at a low dose of AzaCR (0.1 mg/mouse) but was delayed for greater than 6 days at higher doses (0.25 mg/mouse and above). Mesenchymal stem cells (MSCs) in tumors have emerged as progenitors involved in stroma formation and metastasis of cancers, partially owing to their abilities to differentially express paracrine factors related to the proliferation and invasion of cancer cells. Approximately two of every three molecules in mutant LI, approximately one of every eight molecules in mutant LII, and practically no molecules in mutant LIII became glycosylated. Therefore, the present study was aimed at verifying whether MMPs may represent sensitive markers of inflammation in patients with coronary artery disease. Eradication of treponematosis with special reference to the eradication of frambesia in Haiti. Copeptin levels were lower in individuals with BD than in healthy controls. A one-step dual-labeling method for antigen detection in mast cells.

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Aerobactin, but not yersiniabactin, salmochelin, or enterobactin, enables the growth/survival of hypervirulent (hypermucoviscous) Klebsiella pneumoniae ex vivo and in vivo. Thus, RNase-neutralized pancreatic membrane fractions from pig, cow, or sheep are a cheap, easily accessible, and fulfilling alternative to canine microsomes. When humans are exposed to high levels of lead, there is damage to almost all organs and organ systems (most importantly, the central nervous system, kidneys, and blood), which often culminates in death. In each nizoral shampoo dosage case, however, the extraction procedure was one worked out for the fixation on which it was used. How to Identify Patients at Risk of Silent Atrial Fibrillation after Cryptogenic Stroke: Potential Role of P Wave Dispersion. While arthrodesis has been the gold standard of surgical treatment for this condition, significant improvements in total ankle arthroplasty have made it a viable alternative.

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