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Alfatrim (Trimethoprim)

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Alfatrim is a combination of two synthetic (man-made) antibiotics, sulfamethoxazole and trimethoprim. Both drugs reduce the ability of some bacteria to utilize folic acid for growing. Sulfamethoxazole is an anti-bacterial sulfonamide, a sulfa drug.

Other names for this medication:
Altavit, Bacin, Bactekod, Bactrimel, Bactropin, Balsoprim, Biotrim, Cosat, Cotribene, Cotrimox, Cotrimstada, Cotripharm, Cotrix, Cozole, Daiphen, Danferane, Gantrisin, Kemoprim, Megatrim, Neotrim, Omsat, Septran, Servitrim, Sigaprim, Suftrex, Sulbron, Sulfoid, Sulprim, Sultrian, Sultrim, Triforam, Trimaxazole, Trimethazol, Trisul, Trisulfose

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Also known as: Trimethoprim


Alfatrim is effective in a variety of upper and lower respiratory tract infections, renal and urinary tract infections, gastrointestinal tract infections, skin and wound infections, septicaemias and other infections caused by sensitive organisms.

Each Alfatrim tablet contains 80 mg trimethoprim and 400 mg sulfamethoxazole.

Each Alfatrim DS (double strength) tablet contains 160 mg trimethoprim and 800 mg sulfamethoxazole.


Prescribing Alfatrim (sulfamethoxazole and trimethoprim) tablets in the absence of a proven or strongly suspected bacterial infection or a prophylactic indication is unlikely to provide benefit to the patient and increases the risk of the development of drug-resistant bacteria.

Alfatrim should be given with caution to patients with impaired renal or hepatic function, to those with possible folate deficiency (e.g., the elderly, chronic alcoholics, patients receiving anticonvulsant therapy, patients with malabsorption syndrome, and patients in malnutrition states) and to those with severe allergies or bronchial asthma.

Hematological changes indicative of folic acid deficiency may occur in elderly patients or in patients with preexisting folic acid deficiency or kidney failure. These effects are reversible by folinic acid therapy.


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Overdose symptoms may include loss of appetite, vomiting, fever, blood in your urine, yellowing of your skin or eyes, confusion, or loss of consciousness.


Store at room temperature between 20 to 25 degrees C (68 to 77 degrees F) away from moisture, light and heat. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Alfatrim are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Alfatrim is contraindicated in pediatric patients less than 2 months of age.

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