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Alpazepam (Diazepam)

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Diazepam, first marketed as Valium, is a medication of the benzodiazepine family that typically produces a calming effect. It is commonly used to treat a range of conditions including anxiety, alcohol withdrawal syndrome, benzodiazepine withdrawal syndrome, muscle spasms, seizures, trouble sleeping, and restless legs syndrome. It may also be used to cause memory loss during certain medical procedures. It can be taken by mouth, inserted into the rectum, injected into muscle, or injected into a vein. When given into a vein, effects begin in one to five minutes and last up to an hour. By mouth, effects may take 40 minutes to begin.

Other names for this medication:
Almpose, Alpazepam, Alzepam, Anxol, Calmod, Calmpose, Calmtack, Campin, Camrelease, Daize, Depresom, Depsonil, Diaclam, Diaze, Diazecalm, Diazeco, Diazepam, Dipax, Direc, Dizapam, Dizep, Elcion, Elpam, Elpose, Hypose, Imilor, Imipam, Imlor, Juniz, Karpam, Lakpam, Neomesmar, Nindral, Nupose, Osopose, Paciquil, Paxum, Peacin, Placidox, Ralium, Silprex, Sleecalm, Sparlium, Syziral, Valrelease, Verzepam, Vipinta, Zeopse, Zycalm

Similar Products:
Risperdal, Aristocort, Eldepryl, Sumycin, Lopid, Ceclor, Biaxin, Pyridium

Also known as: Diazepam


{name} (diazepam) is a benzodiazepine (ben-zoe-dye-AZE-eh-peen). It is thought that diazepam works by enhancing the activity of certain neurotransmitters in the brain.

{name} is used to treat anxiety disorders, alcohol withdrawal symptoms, or muscle spasms and stiffness.

{name} is sometimes used with other medications to treat seizures.


Take Alpazepam exactly as prescribed by your doctor. Follow the directions on your prescription label and read all medication guides. Your doctor may occasionally change your dose. Never use diazepam in larger amounts, or for longer than prescribed. Tell your doctor if you feel an increased urge to use more of this medicine.

Never share this medicine with another person, especially someone with a history of drug abuse or addiction. MISUSE CAN CAUSE ADDICTION, OVERDOSE, OR DEATH. Keep the medication in a place where others cannot get to it. Selling or giving away this medicine is against the law.

Alpazepam should be used for only a short time. Do not take this medicine for longer than 4 months without your doctor's advice.

Do not stop using this medicine suddenly, even if you feel fine. Stopping suddenly may cause increased seizures or unpleasant withdrawal symptoms. Follow your doctor's instructions about tapering your dose.

You will need frequent medical tests.

Store at room temperature away from moisture, heat, and light. Keep track of your medicine. You should be aware if anyone is using it improperly or without a prescription.

Detailed Alpazepam dosage information


Seek emergency medical attention. An overdose of diazepam can be fatal. Overdose symptoms may include extreme drowsiness, loss of balance or coordination, limp or weak muscles, or fainting.


Store at room temperature away from moisture, heat, and light. After you have stopped using this medicine, flush any unused pills down the toilet.

Keep track of the amount of medicine used from each new bottle. Alpazepam is a drug of abuse and you should be aware if anyone is using your medicine improperly or without a prescription.

Side effects

The most common side effects associated with Alpazepam are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


If Alpazepam is to be combined with other psychotropic agents or anticonvulsant drugs, careful consideration should be given to the pharmacology of the agents to be employed - particularly with known compounds that may potentiate the action of Alpazepam, such as phenothiazines, narcotics, barbiturates, MAO inhibitors and other antidepressants.

The usual precautions are indicated for severely depressed patients or those in whom there is any evidence of latent depression or anxiety associated with depression, particularly the recognition that suicidal tendencies may be present and protective measures may be necessary.

A lower dose is recommended for patients with chronic respiratory insufficiency, due to the risk of respiratory depression.

In debilitated patients, it is recommended that the dosage be limited to the smallest effective amount to preclude the development of ataxia or oversedation (2 mg to 2.5 mg once or twice daily, initially, to be increased gradually as needed and tolerated).

Some loss of response to the effects of benzodiazepines may develop after repeated use of Alpazepam for a prolonged time.

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No previous long-term prospective studies have examined if workers with low cardiorespiratory fitness have an increased risk of cardiovascular mortality due to high physical work demands. Comparison of clasp retention on enamel and composite resin-recontoured abutments following repeated removal in vitro. The changes in the feet were similar to those of the hands, with advanced tarsal bone ages, shortness of the metatarsals and elongation of the second and third toes. Absorption and emission spectral studies of ADR 1 dye interaction with GuHCl reveals that the dye molecule is not in the protonated form in aqueous GuHCl solution, and the dye is confined to two distinguishable microenvironment in the aqueous phase. Multidrug-resistant Escherichia coli, especially a lineage of O25b:H4-ST131, has increased and spread worldwide. Eleven blood samples were taken at fixed times pre-, intra- and postoperatively to determine changes caused by the anesthetic agents on the hemostaseologic parameters during the whole operation.

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This study aimed to investigate the role of intestinal NO in the regulation of apoptosis during fasting in rats. With the use of two microelectrodes, transepithelial potential difference and changes in potential difference in response to passage of current pulses were recorded, and epithelial resistance and the equivalent short-circuit current were calculated. In normotensive Wistar rats, cyclosporine A causes a significant decrease in cardiac beta 1-adrenoceptors without affecting beta 2-adrenoceptors. Computerized dynamic posturography (CDP) provides the opportunity to simultaneously change the interactions between visual, somatosensory, and vestibular inputs, thus giving an indication of the relative importance of these senses in maintaining balance. In our analysis of the MADS domain proteins, we apply for the first time a correlated mutation analysis to a family of interacting proteins. Antiviral therapy was associated with a higher risk for withdrawal due to adverse events than placebo, but risk for serious adverse events did not differ. Nine years since the First Congress of Partisan Medical Officers. The second includes a collection of cell populations found constitutively in all individuals whose specificity for antigen, if any, is being currently investigated. Dextro-rotarory lactic acid and racemic lactic acid in the treatment of psoriasis and parakeratotic dermatosis. Given that AQP9 presumably acts as a channel for metabolites to pass from astrocytes to neurons, the reduced expression of AQP9 at these specific sites may be implicated in the pathogenesis of glaucomatous optic neuropathy.

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nasalis after examining the morphological and osteological characters of the single known specimen of C. Effect of Aqueous Allium cepa and Ixora brachiata Root Extract on Leishmania major Promastigotes. Factors influencing the reinforcing and subjective effects of ephedrine in humans. Although different veterinary schools may cover different elements of the subject and teach it in many different ways, it is important to recognize that this multidisciplinary subject is evolving rapidly. Test-retest differences for medication variables and mood state could not be controlled. Pluripotency marker OCT3/4 expression persisted unexpectedly long in the differentiating EBs. Instillation of imipenem/cilastatin, after debridement and lavage, significantly reduced all variables measured. Cytological analysis of ultraviolet-irradiated Escherichia coli. Clinical and radiologic outcomes associated with the use of dynamic locking screws (DLS) in distal tibia fractures.

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Skeletal and vascular smooth muscle hypertrophy is induced by phosphatidylinositide-3 kinase (PI(3) kinase) via mammalian target of rapamycin (mTOR) and p70S6 kinase (p70S6K). Bidirectional changes to hippocampal theta-gamma comodulation predict memory for recent spatial episodes. Evaluation of their efficacy and possible side effects required accurate knowledge of various methods. Marrying microfluidics and microwells for parallel, high-throughput single-cell genomics. In conclusion, HMGb1 seems a good candidate for the development of medical treatments to be used on chronic or severe wounds. The present work demonstrates the potential of HA to modulate protein release profile from PLGA microparticle formulations produced via spray drying using 3-fluid nozzle. In patients with low-flow AS, AVA(proj) better predicts underlying AS severity and patient outcomes than traditional dobutamine stress echocardiographic indices.

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Understanding the effect the menstrual cycle can have on psychiatric illness, such as premenstrual exacerbations, is important for the holistic care of women with schizophrenia. The largest lesions were treated with staged angiographically guided embolization and excision. To determine whether buried, absorbable, subcuticular sutures increase the degree of inflammation in noncontaminated wounds. It usually occurs in patients with advanced myeloproliferative syndrome. By placing CdTe at the air/water interface, it is revealed in the deposition that the tetrapods experienced a dewetting phenomenon, forming a ribbon structure at the onset of surface pressure with a height corresponding to the length of one tetrapod arm. Sensitivity analyses were performed to identify results according to specific study designs. Effect of cyclodextrin on plasma lipids and cholesterol metabolism in the rat.

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We report for the first time a detailed study of the localization of the main components that constitute the telomeres in Drosophila, HeT-A and TART RNAs and proteins. Both archaeal species and two of the six eubacterial species were detected in the DNA and FISH hybridization experiments. Only through continued quality research can this goal be attained. We performed a prospective, randomized, double-blinded, placebo-controlled study in 60 men without diabetes. We sought to assess the cellular processes that are involved in the early phases of aortic valve disease using a unique animal model of RF-associated AVC. Relation of environmental characteristics to fish assemblages in the upper French Broad River basin, North Carolina.

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The FL signals of rhodamine dye molecules have been several-ten-fold enhanced by introducing the SAM, in comparison with the previous configuration contacting molecules and metal surfaces. Retrospective case-control comparison was made of cases of suicide/undetermined death with living controls using psychological autopsy in South East Scotland. Failure of the cerebrovascular system to maintain function or normative values of several interrelated hemodynamic variables--cerebral blood flow (CBF), oxygen extraction fraction (OEF), cerebral blood volume (CBV), and cerebral metabolic rate of oxygen (CMRO2),--in response to a stress implies a compromise of the normally robust compensatory mechanisms. Thus, the role of the surgeon EW in the legal arena must have the same degree of integrity as the surgeon in his practice with direct patient care and it should be reviewed and subject to regulation. Single-center experience in the treatment of primary testicular lymphoma. Besides the brief description of instruments, the underlying theoretical basis will be presented and limits of the applied methods under ground and microgravity conditions will be discussed.

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The relationship between dosage and utilization of orally administered iron compounds. This regulation of E2F1 transcriptional activity is mediated by a pRb-independent, but Brg1/Brm-dependent mechanism. Most of the authors suggest the heterotopic Mullerian ducts to be the origin of such tumors. Prioritization of inpatient hospital services to prisoners: a method for justifying care and costs. Constructs were cultured either free-swelling for 2 or 4 weeks, under direct mechanical loading for 2 or 4 weeks, or free swelling for 2 weeks followed by 2 weeks of loading. In summer the concentration of formaldehyde in these waters was higher than in winter. Libraries of human rhinovirus-based HIV vaccines generated using random systematic mutagenesis. High senile plaque densities were observed in the cerebral cortex and were correlated with the duration of SDAT. The article describes how university-based evaluators, a state health department, and local program providers collaborated to evaluate 12 projects implementing commercially developed teenage pregnancy prevention (TPP) programs in school settings. The LCGICs were formulated using a newly synthesized polymer having pendant methacrylate groups (in other words, a methacryloyl derived polymer or MDP), amino acid derivatives, water, and Fuji II LC glass.

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The increase in systemic low-grade inflammation induced by periodontitis may alter the effects of obesity on the production of inflammatory molecules, including C-reactive protein (CRP), interleukin (IL)-6, and tumor necrosis factor-alpha (TNF-alpha), in the liver and white adipose tissue (WAT). Spectrographic determination of lead in teeth in normal subjects exposed to saturism. Prostate carcinoma with squamous differentiation: an analysis of 33 cases. State-issued identification cards are a promising data source for neighborhood-level obesity estimates. The uptake by swards of three activation products ((54)Mn, (57)Co and (63)Ni) was studied in a long-term field experiment. Tumor necrosis factor-alpha, sphingosine, ceramide: which is the appropriate marker of inflammation?.

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Using different similarity metrics, we demonstrated that articles linked by SLCs are highly related. Genetic defects in alpha-TTP, like dietary vitamin E deficiency, are associated with infertility, muscular weakness and neurological disorders. Interaction graphics were constructed to study bias in the different settings, and the effect of the different factors on bias was described using linear models. In the thermophilic archaeon Sulfolobus solfataricus a DNA-binding protein is in vitro (Adpribosyl)ated. The aim of our study was to determine the pattern of stroke in patients with an occlusion of the ICA of presumed atherosclerotic origin. This raises the question of whether the cross-linguistic variability found for spatial representations, and the principles on which these are based, may also carry over to the domain of time. Molecular modeling, spectroscopic signature and NBO analysis of some building blocks of organic conductors. Three new species of the genus Austrophthiracarus from New Zealand (Acari: Oribatida: Phthiracaridae). PCBs were found to be the dominant OCs with respective mean concentrations of 55.14 ng g(-1) lipid-mass for egg and 1.26 ng mL(-1) wet-mass for blood.

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The short flights of honeybees indicate a high potential for geitonogamy, and low pollen and seed dispersals suggest strong genetic structure over short distances. However, mutant proteins containing substitutions of any two of these basic amino acids bound RNA weakly. The serum mucoproteins as an aid in the differentiation of neoplastic from primary parenchymatous liver disease. Activities with high spinal loads should be avoided by patients with back problems. The ability of the carbamate pesticide carbaryl (CB) and the organophosphate pesticide trichlorphon (TCL) to inhibit the outgrowth of axon-like processes was studied using mouse N2a neuroblastoma cells induced to differentiate by serum withdrawal. Importance of antioxidant and antiapoptotic effects of beta-receptor blockers in heart failure therapy. By solving a linear stochastic equation, we demonstrate how probability density functions of scattered intensities and order statistics can be used for reconstructing the statistical properties of fluctuating anisotropic polarizabilities. The fate and mobility of copper from chemical root control barriers in soil and leachate. 3D and 4D sonography and magnetic resonance in the assessment of normal and abnormal CNS development: alternative or complementary.

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The database contained 480 records for healthy, term-born children (272 boys and 208 girls born at 37-42 weeks of gestation) aged 9-54 months. It is important that education given in the early period is permanent until the period during which the frequency of crying is increased. The capabilities of all three are demonstrated for characterizing the physicochemical properties of the electron-dense core atrial gland vesicles from Aplysia californica and comparing them with the same properties of the electron lucent red hemiduct vesicles. The Lipid Parameters and Lipoprotein(a) Excess in Hashimoto Thyroiditis. Cases of neural tube defects (including anencephaly and open spina bifida) diagnosed in residents within 100 miles of the US-Mexico border from January 1993 to October 2000 were eligible. To fix the cartilage segments to each other, 6-0 polydioxanone (PDS) suture was used. Factors related to number of present teeth in Korean elderly adults aged 55-84 years. Axonal transport of gangliosides in the visual system of the developing chick embryo. The systemic blood flow in congenital heart disease, with an examination of the validity of the cardiac index. Minimizing asynchronism to improve the performances of anaerobic co-digestion of food waste and corn stover.

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To determine the structure of two multidrug-resistant IncHI1 plasmids carrying blaCTX-M-1 in Escherichia coli isolates disseminated in an equine clinic in the Czech Republic. The conscientious dental practitioner must identify his/her older patients at risk for developing root lesions and place a major emphasis on the prevention and treatment thereof. Sildenafil is a selective inhibitor of the cGMP-specific phosphodiesterase type V (PDE-V) in the corpus cavernosum. The reused skin-graft technique can be used to treat chronic gluteal hidradenitis suppurativa, but long-term outcomes and the reliability of the technique have not been reported. Mouth guards worn during contact sports have been shown to provide considerable protection against traumatic injuries to the teeth and supporting structures. The Vaccine Assessment Committee of the Spanish Association of Pediatrics discusses vaccine developments in 2003 and recommends some modifications to the vaccination schedule. Like the Tob protein, Tob2 inhibited cell cycle progression from the G0/G1 to S phases. Plasma fibrinogen was significantly higher after 24 h of steroid infusion than in the placebo control group. The Ovarian Tumor Index, which combines patient age with specific ultrasonographic markers, is an accurate method for predicting ovarian malignancy in the clinical scenario of suspected adnexal masses. Disturbances in the detection of melanogen by means of the Thormalen test.

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Outcomes of a university-based registered nurse refresher course. Participants learned the locations of real objects in a room and imagined being in their kitchens. The patient underwent total cystectomy and bilateral ureterocutaneostomy with a favorable outcome. Biliary cystic tumors are rare neoplasms occurring in the liver and less frequently in the extrahepatic biliary system. Choline, a precursor for acetylcholine and selective agonist for alpha7nAchR, was administered intrathecally either with, or 30 min after, intrathecal gp120.

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Because of a combination of demographic and social factors, such as the aging of the population in general, increased incidence of diabetes, and more liberal criteria for renal replacement therapy initiation, the proportion of the end-stage renal disease (ESRD) patients with diabetes who are considered elderly is currently the fastest growing segment of incident ESRD population. In this review, the feasibility of gram-negative bacterial secretion systems for the development of anti-virulence agents and possible arenas for their utility in therapeutic intervention of gram-negative bacterial infections such as gastroenteritis, nosocomial infections, and venereal diseases are discussed. After 1 minute and 50 seconds, the crown was removed and polymerization was continued under the following conditions: 20 degrees C air, and water at 0 degrees C, 10 degrees C, 20 degrees C, 30 degrees C, 40 degrees C, 60 degrees C, and 80 degrees C. Recent advances in technology introduce several new interaction methods, potentially leading to more efficient, personalized cognitive gaming experiences. The present results suggest that the HTR3A and DBH genes may participate in the regulation of dopamine and serotonin turnover rates bactrim dose cellulitis in the central nervous system.

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Acute coronary syndromes: the degree and morphology of coronary stenoses. It has been demonstrated that ghrelin plays a major role in the regulation of GH secretion and food intake. In addition, TAF-I KD and histone H1 KD affected the chromatin structure near the ISG promoters. The potential for hydrophobic organochlorine contaminants to be sequestered in submersed aquatic vegetation was evaluated by determining the concentrations of cis- and trans-chlordane, dieldrin, and polychlorinated biphenyls (PCBs) in feral aquatic macrophytes (Hydrilla verticillata (L.f.) Royle) collected from the tidal Potomac River. Simulations occurred in water use rooms containing multiple airborne radon detectors. We aimed at seeing whether the telomerase-negative phenotype of these immortal cells is dominant over telomerase-positive phenotype of other immortal cells in correlation with cellular mortality. The performance of lagoon aging of digested sludge was also compared to the performance of lagoon aging of anaerobically digested and dewatered sludge.

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Although olanzapine is tolerated relatively well in acute overdose, unpredictable and transient fluctuations between central nervous system depression and agitation, frequently associated with miosis, appear to be characteristic findings in moderate to high olanzapine overdoses. PR-B isoform content significantly diminished during proestrus-estrus transition both in mated and nonmated female rats. We retrospectively evaluated clinical data of pregnant women in whom an elevated aPTT was noted on routine prenatal testing. It is still unclear which prometrium progesterone reviews scavenger and which inhibitor should be given when and in which dosage in order to improve the outcome of sepsis and septic shock. However, to the best of our knowledge, the cytologic findings of giant lamellar bodies have not been reported. Jaw clenching with a hard splint caused activity in the widest brain regions, including the associated area with motor coordination. Interleukin-23 in early disease development in rheumatoid arthritis. 6 PKC inhibitor Ro 31-8220, but not Go 6976, significantly inhibited the LPA-induced cyclic AMP potentiation.

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Analyses of chimeric and deletion mutants of the IL-2R beta subunit have revealed that its intracellular domain critically and selectively influences high affinity ligand binding mediated through the extracellular domains of the alpha beta-heterodimeric receptor. Such a region might be a critical node in the representation of vocal communication sounds, underlying the recognition of vocalization type, caller and social context. NEED for a national health program: excerpts from testimony presented before the Senate Committee on Education and Labor. Although optometrists welcomed the opportunity to develop their professional skills and knowledge, enhanced schemes must also provide a sufficient financial incentive so as not to compromise the profitability of their business. To screen for and analyze the effects of compounds that interfere with Tat transactivation, we developed several cell-based reporter systems in which enhanced green fluorescence protein is a direct and quantitative marker of HIV-1 expression or Tat-dependent long terminal repeat activity. High serum level of C-reactive protein is associated with worse outcome of patients with advanced-stage NSCLC treated with erlotinib. This feature makes it applicable to many newly sequenced genomes that do not have extensive experimental information. This indicated that the improved ion conductivity was dependent on the reduced crystallinity that was correlated with the d-spacing of MMT. Contributing to the difficulty is the lack of studies that have assessed a population of patients presenting with unilateral leg swelling.

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A less invasive technique of balloon rupture in the female patient, using a peri-catheter urethral route, is described. To this aim, different motion models that are applicable in real-time are presented and the methods are integrated into a needle puncture training simulation framework, which can be used for simulated vantin 200 mg biopsy or vessel puncture in the liver. Based on in-vitro colony assays of patients with CN, it is nowadays suggested that a disturbance in growth factor receptor binding or post-receptor signal transduction is the cause of this rare benign haematological disorder. Health-related quality of life and psychological well-being in patients with benign prostatic hyperplasia. The analysis suggests that the two tests, which compare the medical utilization of informed and uninformed consumers, are not valid. Surprisingly, this screen identified Apc5, although it does not harbor a classical RNA binding domain. Expectations are that duplicate reports and data gathering will be eliminated. Acute intestinal ischemia reperfusion (IR) injury is often associated with intestinal epithelial barrier (IEB) dysfunction.

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To diagnose the disease in its early stage is infrequent as the symptoms are usually trivial and patients only present in late stages. HDL-C/HDL-P Ratio: A Measure of Reverse Cholesterol Transport Rather Than HDL Functionality. We show that NSPHAN is expressed throughout emerging blade primordia in the wild type and becomes localized to the middle mesophyll in the expanding lamina. Peripheral blood lymphocytes (PBL) obtained from chickens infected with E. Expression of mutant receptors in a wild-type strain interfered with chemotaxis to only a minor extent. Diuretic pretreatment and the concomitant volume depletion did not prevent acute foot swelling on nifedipine, although the absolute foot volume remained lower after such pretreatment.

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