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Alpostin (Alprostadil)

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Alpostin is a medication used in the management and treatment of erectile dysfunction in males and for temporary patency of ductus arteriosus in newborns with congenital heart diseases before surgical intervention. It is in the prostaglandin analog class of medications.

Other names for this medication:
Alpostin, Caverject, Edex, Muse, Prostin, Vitaros

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Also known as: Alprostadil


{name} urethral suppository is used to treat men who have erectile dysfunction (also called sexual impotence). It belongs to a group of medicines called vasodilators that can increase blood flow by expanding blood vessels. {name} causes an erection because it increases the blood flow to the penis.

{name} should not be used as a sexual aid by men who do not have erectile dysfunction. If the medicine is not used properly, permanent damage to the penis and loss of the ability to have erections could result.

{name} is available only with your doctor's prescription.


Read the Patient Information Leaflet provided by your pharmacist before you start using Alpostin and each time you get a refill. Learn all usage instructions in the product package. If any of the information is unclear, consult your doctor or pharmacist. This medication is used by inserting the suppository into the penis as directed by your doctor. Dosage is based on your medical condition and response to therapy. This medication should usually work within 5-10 minutes to produce an erection that lasts for about 30-60 minutes. The manufacturer recommends that you use no more than 2 doses in a 24-hour period. Inform your doctor if your condition persists or worsens (e. g. , the drug does not produce an erection or it becomes more difficult to get an erection).


If overdose is suspected, contact a poison control center or emergency room immediately. US residents can call their local poison control center at 1-800-222-1222. Canada residents can call a provincial poison control center. Symptoms of overdose may include: fainting, painful/prolonged erection.


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The most common side effects associated with Alpostin are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Do not use Alpostin if you have a penile implant unless advised by doctor.

If too much of this medicine is used, the erection lasts too long and does not reverse when it should. This condition is called priapism. If the erection is not reversed, the blood supply to the penis may be cut off and permanent damage may occur.

Contact your doctor immediately if the erection lasts longer than 4 hours or if it becomes painful. This may be a sign of priapism and must be treated right away to prevent permanent damage.

If you notice bleeding at the place where you injected the medicine, put pressure on the spot until the bleeding stops. If it doesn't stop within 5 minutes, check with your doctor. If you have an infection that is spread through blood, this could increase the risk of giving the infection to your sexual partner.

This medicine does not prevent pregnancy. Use birth control if you do not want pregnancy to occur.

This medicine will not protect you or your partner from sexually transmitted diseases.

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