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Amitrol (Amitriptyline)

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Amitrol is an antidepressant medication that is sometimes prescribed off-label to manage chronic back pain. It is one of the drugs in a class of drugs known as tricyclic antidepressants. Amitrol is not a narcotic (opioid) drug, and there is not usually an addiction risk with the medication.

Other names for this medication:
Abamax, Amiclozor, Amiline, Amimax, Amitrip, Amitriptyline, Amitrix, Amitryn, Amitryptyline, Amitwix, Amize, Amizep, Amline, Amrea, Amsha, Amtipax, Aptric, Arpidox, Axtrip, Bluneel, Cotrip, Emotrip, Endep, Eptanol, Estiline, Gentrip, Goldep, Kamitrin, Latilin, Librodep, Limbitrol, Limbival, Lodep, Maxitrip, Mitrip, Mitryp, Nextrip, Normaline, Psycomer, Raitrip, Ristryl, Sarotena, Sereval, Tablin, Tadamit, Teedep, Tridep, Triplent, Tryptomec, Typlin

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Also known as: Amitriptyline


{name} (amitriptyline) is a tricyclic antidepressant with sedative effects. Amitriptyline affects certain chemical messengers (neurotransmitters) that communicate between brain cells and help regulate mood.

{name} is a prescription medicine used to treat symptoms of depression.


Usual Adult Dose for Depression:

OUTPATIENTS: -Initial dose: 75 mg orally per day in divided doses; this may be increased to 150 mg/day (if needed) -Maintenance dose: 40 to 100 mg orally per day -Maximum dose: 150 mg/day Alternate outpatient treatment regimen: 50 to 100 mg orally as a single dose at bedtime; this may be increased by 25 or 50 mg as needed at bedtime to a total of 150 mg/day INPATIENTS: -Initial dose: 100 mg orally per day -Maintenance dose: 40 to 100 mg orally as a single dose at bedtime -Maximum dose: 300 mg/day Comments: -Dose increases should preferably be made in the late afternoon or at bedtime due to the sedative effect. -The full therapeutic effect may take as long as 30 days to develop. -Maintenance doses should be reduced to the lowest amount that will maintain relief of symptoms when satisfactory improvement has been obtained. -Maintenance therapy should be continued for 3 months or longer to lessen the possibility of relapse. Use: Relief of symptoms of depression

Usual Geriatric Dose for Depression:

10 mg orally 3 times a day AND 20 mg orally once a day at bedtime Comments: -The full therapeutic effect may take as long as 30 days to develop. -Elderly patients should be monitored carefully and serum levels obtained as clinically appropriate. -Dose adjustments should be made according to clinical response. Use: Relief of symptoms of depression

Usual Pediatric Dose for Depression:

12 years or older: 10 mg orally 3 times a day AND 20 mg orally once a day at bedtime Comments: -The full therapeutic effect may take as long as 30 days to develop. -Dose adjustments should be made according to clinical response. Use: Relief of symptoms of depression

Detailed Amitrol dosage information


If you overdose Amitrol and you don't feel good you should visit your doctor or health care provider immediately. Symptoms of Amitrol overdosage: seizures, loss of consciousness for a period of time, seeing things or hearing voices that do not exist, agitation, feeling drowsy, rigid muscles, vomiting, high temperature, cold body temperature, problems concentrating, abnormal heartbeats, confusion.


Store at room temperature between 20 and 25 degrees C (68 and 77 degrees F) away from moisture and heat. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Amitrol are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Do not take Amitrol if you are allergic to Amitrol components. Do not take Amitrol if you are pregnant, planning to become pregnant, or are breast-feeding. Be careful with Amitrol if you suffer from or have a history of a history of heart attack, stroke, bipolar disorder (manic-depression), schizophrenia or other mental illness, diabetes, overactive thyroid, glaucoma, problems with urination, heart disease, seizures. Be careful with Amitrol if you are taking guanethidine (Ismelin), disulfiram (Antabuse), heart rhythm medications such as flecainide (Tambocor), propafenone (Rhythmol), quinidine (Cardioquin, Quinidex, Quinaglute), cimetidine (Tagamet). Avoid alcohol. Be careful! Taking Amitrol you can become suicidal. Be careful when you are driving or operating machinery. Be careful with Amitrol if you are going to have a surgery. It can be dangerous to stop Amitrol taking suddenly.

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Effects of aging and caloric restriction on I-compounds in liver, kidney and white blood cell DNA of male Brown-Norway rats. The origin of NIS is outlined briefly and some fundamental clinical and experimental facts are presented, all of which stress the importance of the acute blockade of postsynaptic DA-ergic receptors. Quantum confinement in nanoribbons enhances the gap sizes, for which both the armchair and zigzag ones have a gap scaling rule inversely proportional to the ribbon width. Isolation and characterization of zinc coproporphyrin I: a major fluorescent component in meconium. Risks are not necessarily reduced by avoiding certain substances but by healthy and well-balanced nutrition.

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Combination treatment of CDK4/6 inhibitor Palbociclib and MEK inhibitor PD0325901 was tested in KRAS-mutant, BRAF-mutant CRC, normal colon epithelial lines and xenografts models to determine their efficacy and toxicity and to monitor the changes in the gene signature. Encapsulated Ole e 1 induced specific and long-lasting antibodies that were predominantly of the IgG2a isotype. The new 3D template of the auricle and guide plate may be a major contribution to the engraving, assembling and localization of the microtia auricle in auricular reconstruction. ON THE IMPORTANCE OF CORTICOSTEROID THERAPY FOR SURGICAL PRACTICE. Content of protein fractions of blood serum in families of patients with cerebral ischemia. Diphosphines possessing electronically different donor groups: synthesis and coordination chemistry of the unsymmetrical Di(N-pyrrolyl)phosphino-functionalized dppm analogue Ph2PCH2P(NC4H4)2. Application of isotope dilution analysis to the determination of sulfate in glycoproteins and oligosaccharides.

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Won Moon and colleagues at University of California - Los Angeles (UCLA). A total of 412 Mainland Chinese university students were recruited in Hong Kong by an online survey. Pteridine levels from supernatants of mixed lymphocyte cultures and from urinary samples of allogeneic kidney transplant recipients were measured by high-pressure liquid chromatography. Probiotic organisms are also available commercially in milk, sour milk, ice cream and other foods. There was elavil 25mg tab only little degradation of protein and lipid bodies, and almost no chloroplast formation in the excised radish cotyledon treated with 1 mumol/L NCS. The effect of wilting on the microbial and chemical composition of ensiled maize plants was studied. Results revealed equivalent findings for our Hispanic subjects and the English-speaking samples utilized in the original normative studies within the United States. tumefaciens, we could get about 1060 transformants per 106 fungal spores.

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Moreover, the thalamus is engaged by tasks requiring multiple cognitive functions. Furthermore, simulated analysis of the LTBP1 CNV using mock samples prepared by mixing vectors in varying proportions showed that this analytical method allowed correct determination of the LTBP1 copy number. The in vitro transfection of COS-7 cells with mutant constructs demonstrated a significantly decreased accumulation of inositol phosphate. The damaged types of eustachian tube function in the patients of nasopharyngeal carcinoma after radiotherapy. An enzyme that catalyzes the interconversion of cortisol and cortisone, 11 beta-hydroxysteroid dehydrogenase, may enalapril maleate tablet uses in malayalam be defective in an autosomal recessive form of hypertension termed apparent mineralocorticoid excess. We sought to assess the predictive value of inflammation and extracellular matrix (ECM) remodeling biomarkers in late mitral restenosis after PMC. Comparison of blood levels with oral and intramuscular diphenylhydantoin. The interactions of selezen (imidazole salicylate) with human blood components were studied by equilibrium dialysis. A whole head MEG study of the amplitude-modulation-following response: phase coherence, group delay and dipole source analysis.

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It is important for patients with sickle cell disease to have periodic examinations by ophthalmologists, because the early identification of peripheral retinal disease can be adequately treated, with preservation of vision. With regard to ethical issues related to the studies on patients with COPD, the phenergan tablets side effects use of animal models of COPD is inevitable. Abnormalities of gastrointestinal motility in children with nonulcer dyspepsia and in children with gastroesophageal reflux disease. Attitudes and opinions of evidence-based practice among hand therapists: a survey study. The advantages and disadvantages of various sensor types are discussed, and prospects and challenges for future development of these sensors are presented. An adapted antimicrobial treatment improves the digestive symptoms. All the subjects were normal volunteers, ambulatory, asymptomatic and free from chronic or acute illness.

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Dysfunction of telomeres was demonstrated in primary sclerosing cholangitis patients more than inflammatory bowel disease and healthy controls patients, which attests to genetic instability and immunosenescence. To define epidemiologic and clinical characteristics of newly diagnosed pediatric inflammatory bowel disease (IBD) in a large population-based model. Murine lymphoma alkaline phosphatase: a cell membrane carcinofetal enzyme. MRI-guided vacuum-assisted biopsy is a fast, safe, and accurate alternative to surgical biopsy for breast lesions detected on MRI. These limitations may be overcome by the use of the embedment-free electron microscopy (EF-EM). Colonisation of antibiotic resistant bacteria in a cohort of HIV infected children in Ghana.

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Ruptured anterior talofibular ligament: a simplified procedure for late repair. Geographical variability in quantitative traits in populations of Drosophila subobscura. We calculated dose contributions from neutrons, protons, deutrons, tritons and He-3 that are produced at the time of photoneutron interactions in the body and that would not have been accounted for by conventional radiation oncology dosimetry. We have successfully established 16 stable murine hybridomas that secrete monoclonal antibodies specific for human DNA polymerase alpha. In the majority of our examples, DD is able to find the global minimum within a minute. These fractures span an extensive spectrum of severity across age groups and demographics. A study of the nucleus-plasma ratio in large alveolar cells of the normal lung and after its sensory denervation. This was further complicated with thrombosis of the dissected artery and subsequent emboli causing acute posterior circulation infarctions. Also attention was given to the future implementation of two new chapters of the United States Pharmacopoeia (USP) stating limit concentrations of elemental impurities.

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