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Amitrol (Amitriptyline)
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Amitrol

Amitrol is an antidepressant medication that is sometimes prescribed off-label to manage chronic back pain. It is one of the drugs in a class of drugs known as tricyclic antidepressants. Amitrol is not a narcotic (opioid) drug, and there is not usually an addiction risk with the medication.

Other names for this medication:
Abamax, Amiclozor, Amiline, Amimax, Amitrip, Amitriptyline, Amitrix, Amitryn, Amitryptyline, Amitwix, Amize, Amizep, Amline, Amrea, Amsha, Amtipax, Aptric, Arpidox, Axtrip, Bluneel, Cotrip, Emotrip, Endep, Eptanol, Estiline, Gentrip, Goldep, Kamitrin, Latilin, Librodep, Limbitrol, Limbival, Lodep, Maxitrip, Mitrip, Mitryp, Nextrip, Normaline, Psycomer, Raitrip, Ristryl, Sarotena, Sereval, Tablin, Tadamit, Teedep, Tridep, Triplent, Tryptomec, Typlin

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Also known as: Amitriptyline

Description

{name} (amitriptyline) is a tricyclic antidepressant with sedative effects. Amitriptyline affects certain chemical messengers (neurotransmitters) that communicate between brain cells and help regulate mood.

{name} is a prescription medicine used to treat symptoms of depression.

Dosage

Usual Adult Dose for Depression:

OUTPATIENTS: -Initial dose: 75 mg orally per day in divided doses; this may be increased to 150 mg/day (if needed) -Maintenance dose: 40 to 100 mg orally per day -Maximum dose: 150 mg/day Alternate outpatient treatment regimen: 50 to 100 mg orally as a single dose at bedtime; this may be increased by 25 or 50 mg as needed at bedtime to a total of 150 mg/day INPATIENTS: -Initial dose: 100 mg orally per day -Maintenance dose: 40 to 100 mg orally as a single dose at bedtime -Maximum dose: 300 mg/day Comments: -Dose increases should preferably be made in the late afternoon or at bedtime due to the sedative effect. -The full therapeutic effect may take as long as 30 days to develop. -Maintenance doses should be reduced to the lowest amount that will maintain relief of symptoms when satisfactory improvement has been obtained. -Maintenance therapy should be continued for 3 months or longer to lessen the possibility of relapse. Use: Relief of symptoms of depression

Usual Geriatric Dose for Depression:

10 mg orally 3 times a day AND 20 mg orally once a day at bedtime Comments: -The full therapeutic effect may take as long as 30 days to develop. -Elderly patients should be monitored carefully and serum levels obtained as clinically appropriate. -Dose adjustments should be made according to clinical response. Use: Relief of symptoms of depression

Usual Pediatric Dose for Depression:

12 years or older: 10 mg orally 3 times a day AND 20 mg orally once a day at bedtime Comments: -The full therapeutic effect may take as long as 30 days to develop. -Dose adjustments should be made according to clinical response. Use: Relief of symptoms of depression

Detailed Amitrol dosage information

Overdose

If you overdose Amitrol and you don't feel good you should visit your doctor or health care provider immediately. Symptoms of Amitrol overdosage: seizures, loss of consciousness for a period of time, seeing things or hearing voices that do not exist, agitation, feeling drowsy, rigid muscles, vomiting, high temperature, cold body temperature, problems concentrating, abnormal heartbeats, confusion.

Storage

Store at room temperature between 20 and 25 degrees C (68 and 77 degrees F) away from moisture and heat. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Amitrol are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Do not take Amitrol if you are allergic to Amitrol components. Do not take Amitrol if you are pregnant, planning to become pregnant, or are breast-feeding. Be careful with Amitrol if you suffer from or have a history of a history of heart attack, stroke, bipolar disorder (manic-depression), schizophrenia or other mental illness, diabetes, overactive thyroid, glaucoma, problems with urination, heart disease, seizures. Be careful with Amitrol if you are taking guanethidine (Ismelin), disulfiram (Antabuse), heart rhythm medications such as flecainide (Tambocor), propafenone (Rhythmol), quinidine (Cardioquin, Quinidex, Quinaglute), cimetidine (Tagamet). Avoid alcohol. Be careful! Taking Amitrol you can become suicidal. Be careful when you are driving or operating machinery. Be careful with Amitrol if you are going to have a surgery. It can be dangerous to stop Amitrol taking suddenly.

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We reviewed clinical, reoperation, and autopsy series to determine the incidence of peritoneal seeding following colon cancer resection. Out of these lncRNAs, 7,863 and 5,561 lncRNAs were identified from osmotic stress-treated leaf and root samples, respectively. Ureteroscopy and holmium: YAG laser lithotripsy: an emerging definitive management strategy for symptomatic ureteral calculi in pregnancy. There was significant counterclockwise rotation of the mandible, and clockwise rotation and distal displacement of the maxilla after treatment. We evaluate the clinical outcome in each patient at 10 years after the operation. Utilization of health services by poor children since advent of medicaid. PALLIATIVE THERAPY OF NEOPLASTIC STENOSIS OF THE ESOPHAGUS AND CARDIA WITH THE AID OF PROSTHESES.

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Effects of aging and caloric restriction on I-compounds in liver, kidney and white blood cell DNA of male Brown-Norway rats. The origin of NIS is outlined briefly and some fundamental clinical and experimental facts are presented, all of which stress the importance of the acute blockade of postsynaptic DA-ergic receptors. Quantum confinement in nanoribbons enhances the gap sizes, for which both the armchair and zigzag ones have a gap scaling rule inversely proportional to the ribbon width. Isolation and characterization of zinc coproporphyrin I: a major fluorescent component in meconium. Risks are not necessarily reduced by avoiding certain substances but by healthy and well-balanced nutrition.

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Combination treatment of CDK4/6 inhibitor Palbociclib and MEK inhibitor PD0325901 was tested in KRAS-mutant, BRAF-mutant CRC, normal colon epithelial lines and xenografts models to determine their efficacy and toxicity and to monitor the changes in the gene signature. Encapsulated Ole e 1 induced specific and long-lasting antibodies that were predominantly of the IgG2a isotype. The new 3D template of the auricle and guide plate may be a major contribution to the engraving, assembling and localization of the microtia auricle in auricular reconstruction. ON THE IMPORTANCE OF CORTICOSTEROID THERAPY FOR SURGICAL PRACTICE. Content of protein fractions of blood serum in families of patients with cerebral ischemia. Diphosphines possessing electronically different donor groups: synthesis and coordination chemistry of the unsymmetrical Di(N-pyrrolyl)phosphino-functionalized dppm analogue Ph2PCH2P(NC4H4)2. Application of isotope dilution analysis to the determination of sulfate in glycoproteins and oligosaccharides.

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Dysfunction of telomeres was demonstrated in primary sclerosing cholangitis patients more than inflammatory bowel disease and healthy controls patients, which attests to genetic instability and immunosenescence. To define epidemiologic and clinical characteristics of newly diagnosed pediatric inflammatory bowel disease (IBD) in a large population-based model. Murine lymphoma alkaline phosphatase: a cell membrane carcinofetal enzyme. MRI-guided vacuum-assisted biopsy is a fast, safe, and accurate alternative to surgical biopsy for breast lesions detected on MRI. These limitations may be overcome by the use of the embedment-free electron microscopy (EF-EM). Colonisation of antibiotic resistant bacteria in a cohort of HIV infected children in Ghana.

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Ruptured anterior talofibular ligament: a simplified procedure for late repair. Geographical variability in quantitative traits in populations of Drosophila subobscura. We calculated dose contributions from neutrons, protons, deutrons, tritons and He-3 that are produced at the time of photoneutron interactions in the body and that would not have been accounted for by conventional radiation oncology dosimetry. We have successfully established 16 stable murine hybridomas that secrete monoclonal antibodies specific for human DNA polymerase alpha. In the majority of our examples, DD is able to find the global minimum within a minute. These fractures span an extensive spectrum of severity across age groups and demographics. A study of the nucleus-plasma ratio in large alveolar cells of the normal lung and after its sensory denervation. This was further complicated with thrombosis of the dissected artery and subsequent emboli causing acute posterior circulation infarctions. Also attention was given to the future implementation of two new chapters of the United States Pharmacopoeia (USP) stating limit concentrations of elemental impurities.

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