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Amiwel (Amitriptyline)

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Amiwel is used to treat mental/mood problems such as depression. Amiwel may help improve mood and feelings of well-being, relieve anxiety and tension, help you sleep better, and increase your energy level. Amiwel belongs to a class of medications called tricyclic antidepressants. It works by affecting the balance of certain natural chemicals in the brain.

Other names for this medication:
Amiclozor, Amiline, Amimax, Amitin, Amitone, Amitop, Amitrim, Amitrol, Amitryptyline, Amitwix, Amity, Amiwel, Amixide, Amizep, Amoten, Amrea, Amtran, Aptric, Arpidox, Axtrip, Bluneel, Chlotrip, Cotrip, Crypton, Eliwel, Emotrip, Eptanol, Gentrip, Goldep, Latilin, Mitrip, Nextrip, Raitrip, Relidep, Sarotena, Tadamit, Trixide, Tryline, Tryptomec, Typteez, Vanatrip, Zodep

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Also known as: Amitriptyline


{name} (amitriptyline) is a tricyclic antidepressant with sedative effects. Amitriptyline affects certain chemical messengers (neurotransmitters) that communicate between brain cells and help regulate mood.

{name} is a prescription medicine used to treat symptoms of depression.


Usual Adult Dose for Depression:

OUTPATIENTS: -Initial dose: 75 mg orally per day in divided doses; this may be increased to 150 mg/day (if needed) -Maintenance dose: 40 to 100 mg orally per day -Maximum dose: 150 mg/day Alternate outpatient treatment regimen: 50 to 100 mg orally as a single dose at bedtime; this may be increased by 25 or 50 mg as needed at bedtime to a total of 150 mg/day INPATIENTS: -Initial dose: 100 mg orally per day -Maintenance dose: 40 to 100 mg orally as a single dose at bedtime -Maximum dose: 300 mg/day Comments: -Dose increases should preferably be made in the late afternoon or at bedtime due to the sedative effect. -The full therapeutic effect may take as long as 30 days to develop. -Maintenance doses should be reduced to the lowest amount that will maintain relief of symptoms when satisfactory improvement has been obtained. -Maintenance therapy should be continued for 3 months or longer to lessen the possibility of relapse. Use: Relief of symptoms of depression

Usual Geriatric Dose for Depression:

10 mg orally 3 times a day AND 20 mg orally once a day at bedtime Comments: -The full therapeutic effect may take as long as 30 days to develop. -Elderly patients should be monitored carefully and serum levels obtained as clinically appropriate. -Dose adjustments should be made according to clinical response. Use: Relief of symptoms of depression

Usual Pediatric Dose for Depression:

12 years or older: 10 mg orally 3 times a day AND 20 mg orally once a day at bedtime Comments: -The full therapeutic effect may take as long as 30 days to develop. -Dose adjustments should be made according to clinical response. Use: Relief of symptoms of depression

Detailed Amiwel dosage information


If you overdose Amiwel and you don't feel good you should visit your doctor or health care provider immediately. Symptoms of Amiwel overdosage: seizures, loss of consciousness for a period of time, seeing things or hearing voices that do not exist, agitation, feeling drowsy, rigid muscles, vomiting, high temperature, cold body temperature, problems concentrating, abnormal heartbeats, confusion.


Store at room temperature between 20 and 25 degrees C (68 and 77 degrees F) away from moisture and heat. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Amiwel are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


You should not use Amiwel if you are allergic to amitriptyline, or:

if you have recently had a heart attack.

Do not use Amiwel if you have used an MAO inhibitor in the past 14 days. A dangerous drug interaction could occur. MAO inhibitors include isocarboxazid, linezolid, methylene blue injection, phenelzine, rasagiline, selegiline, tranylcypromine, and others.

Tell your doctor if you have used an "SSRI" antidepressant in the past 5 weeks, such as citalopram, escitalopram, fluoxetine (Prozac), fluvoxamine, paroxetine, sertraline (Zoloft), trazodone, or vilazodone.

To make sure Amiwel is safe for you, tell your doctor if you have ever had:

bipolar disorder (manic-depression) or schizophrenia; mental illness or psychosis; liver disease; heart disease; a heart attack, stroke, or seizures; diabetes (amitriptyline may raise or lower blood sugar); glaucoma; or problems with urination.

Some young people have thoughts about suicide when first taking an antidepressant. Your doctor should check your progress at regular visits. Your family or other caregivers should also be alert to changes in your mood or symptoms.

Tell your doctor if you are pregnant or breastfeeding.

Amiwel is not approved for use by anyone younger than 12 years old.

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Draft Genome Sequence of Aliivibrio fischeri Strain 5LC, a Bacterium Retrieved from Gilthead Sea Bream (Sparus aurata) Larvae Reared in Aquaculture. Five patients had liver transplantation, three had kidney transplantation, one had heart transplantation and one had lung transplantation. Impact of pulmonary and extrapulmonary tuberculosis infection in kidney transplantation: a nationwide population-based study in Taiwan. These data demonstrate metabolite profiles and microbial communities are species-specific and are correlated to one another. Staphylococcus aureus is highly pathogenic and can cause diseases in both humans and domestic animals. The animals with cirrhosis showed an impairment in active avoidance behavior and spatial memory, regardless of the diet they received.

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Effect of Oral Administration of Gnidia Stenophylla Gilg Aqueous Root Extract on Food Intake and Histology of Gastrointestinal Tract in Mice. We have studied the role of p38 mitogen-activated protein kinases (MAPKs) in the meiotic maturation of Xenopus oocytes. In mechanically ventilated, critical care patients, indirect calorimetry was used to measure resting metabolic rate for 7 days. Anatomical studies using retrograde neuronal tracers were carried out to identify pudendal motoneurons and putative lumbosacral interneurons involved in the generation of penile reflexes in the adult male rat (Sprague-Dawley). Negative relationship between glucose utilization rate and insulin release was linear (correlation -.85), suggesting that fat feeding induced insulin resistance. Prevalence of congenital and acquired toxoplasmic uveitis as evidenced by two serologic methods. The aim of this study was to evaluate the usefulness of contrast-enhanced ultrasound for the differentiation of hepatocellular carcinomas from dysplastic nodules in cirrhotic patients with small liver nodules showing atypical or not coincidental typical vascular pattern on two dynamic imaging techniques (computed tomography and magnetic resonance imaging). We show that gamma2XL failed to localize to the cell surface when it was coexpressed with the alpha2 and beta1 subunits in human embryonic kidney 293 cells. Biglycan and ACAT1 expression were significantly decreased, and aortic free cholesterol: cholesterol ester ratios were increased in these mice.

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The uptake of 3H-thymidine in Mycobacterium leprae inoculated mouse macrophage cultures as a rapid indicator of bacillary viability. A conventional abdominal duplex US examination was also performed by a certified vascular ultrasonographer. Novel Parameter of Corneal Biomechanics That Differentiate Normals From Glaucoma. It was found that the affinity of the enzyme for ABTS decreases with increasing pH, and that with higher ABTS concentrations the pH optima of the reaction are shifted towards neutrality. This results in diverse outcomes ranging from long-term remission to early recurrence. It appears that the kinetics of Cr(V) formation and decomposition depended on the bacterial growth phase and on the species. Survival rates of children with severe neurologic disabilities: a review. The results suggest that U2 small nuclear ribonucleoprotein particles normally participate in stable complexes with a limiting splicing factor prior to formation of U2-intron branchpoint base pairs. We introduce a gas chromatography detection approach that uses diode array detection operated in series with flame ionisation detection and demonstrate the utility of the detection approach for determination of volatile organic compounds.

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Abundance and species diversity of tabanids (Diptera) in the biosphere reserve Ipassa-Makokou (Gabon) during the rainy season. Neonatal outcome of singleton term breech deliveries in Norway from 1991 to 2011. Therapy of cluster headache with histamine H1 and H2 receptor antagonists. Anismus as a cause of functional constipation--experience bactrim class drug from Serbia. A scanning electron microscope (SEM) was then used to determine the nanoablated line width to high accuracy, from which the lateral spot size and hence resolution of the LSM can be determined. Nine healthy participants performed four 3D center-out reaching tasks in four different sessions while wearing a passive robotic exoskeleton at their right upper limb. Satisfaction was excellent in 17 patients, good in 5, and unsatisfactory in 1.

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The venom of the honeybee (Apis mellifera): free amino acids and peptides. A lack of dietary folic acid can lead to folic acid deficiency and result in several health problems, including macrocytic anemia, elevated plasma homocysteine, cardiovascular disease, birth defects, carcinogenesis, muscle weakness, and walking difficulty. In all instances it was possible, partly by transferring insulin uptake during the day and night to two subcutaneous injections, to improve conventional control even after the infusion period was over. Polymorphism at the G6pd and 6Pgd loci in Drosophila melanogaster. Because of the flexibility of the chest in infants, surgical repair should be performed by primary closure in the neonatal period. Importance of the novel organic cation transporter 1 for tyrosine kinase inhibition by saracatinib in rheumatoid arthritis synovial fibroblasts. Isoniazid resistance of exponentially growing Mycobacterium smegmatis biofilm culture. This review provides a broad overview of the range of potential transport systems now micardis 80mg tablet thought to be involved in the uptake, distribution and homeostasis of transition metals in plants. Suprarenal aortic constriction was adjusted to reduce renal perfusion pressure below the autoregulatory range in both groups of dogs. This leads to a complex array of global as well as specific defense responses, which are often associated with plant cell death and subsequent arrest of the invader.

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