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Amtran (Amitriptyline)

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Amtran is sometimes used off-label, meaning not FDA approved, for certain conditions. Some providers will use this medication to treat nerve pain. This can be helpful for people who have diabetes or fibromyalgia and haven't felt relief with other medications.

Other names for this medication:
Amidez, Amimax, Amitin, Amitrim, Amitrip, Amitrol, Amitryptyline, Amitwix, Amity, Amline, Amoten, Amrea, Amypres, Anitryp, Aptric, Axtrip, Crypton, Kamitrin, Latilin, Latiln, Lodep, Mitrip, Nextrip, Normaline, Psycomer, Sarotena, Sereval, Tridep, Trixide, Typlin, Vanatrip

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Also known as: Amitriptyline


Amtran target is the treatment of depression. Amtran is acting by increasing the amounts of certain natural substances in the brain that are needed to maintain mental balance. It is tricyclic antidepressant. Generic name of Amtran is Amitriptyline. Amtran is also known as Amitriptyline, Amitryptyline, Amidon, Amitryn, Tryptanol, Endep, Elatrol, Tryptizol, Trepiline, Laroxyl, Saroten, Triptyl, Amitrip. Brand names of Amtran are Amtran, Endep, Vanatrip.


Usual Adult Dose for Depression:

OUTPATIENTS: -Initial dose: 75 mg orally per day in divided doses; this may be increased to 150 mg/day (if needed) -Maintenance dose: 40 to 100 mg orally per day -Maximum dose: 150 mg/day Alternate outpatient treatment regimen: 50 to 100 mg orally as a single dose at bedtime; this may be increased by 25 or 50 mg as needed at bedtime to a total of 150 mg/day INPATIENTS: -Initial dose: 100 mg orally per day -Maintenance dose: 40 to 100 mg orally as a single dose at bedtime -Maximum dose: 300 mg/day Comments: -Dose increases should preferably be made in the late afternoon or at bedtime due to the sedative effect. -The full therapeutic effect may take as long as 30 days to develop. -Maintenance doses should be reduced to the lowest amount that will maintain relief of symptoms when satisfactory improvement has been obtained. -Maintenance therapy should be continued for 3 months or longer to lessen the possibility of relapse. Use: Relief of symptoms of depression

Usual Geriatric Dose for Depression:

10 mg orally 3 times a day AND 20 mg orally once a day at bedtime Comments: -The full therapeutic effect may take as long as 30 days to develop. -Elderly patients should be monitored carefully and serum levels obtained as clinically appropriate. -Dose adjustments should be made according to clinical response. Use: Relief of symptoms of depression

Usual Pediatric Dose for Depression:

12 years or older: 10 mg orally 3 times a day AND 20 mg orally once a day at bedtime Comments: -The full therapeutic effect may take as long as 30 days to develop. -Dose adjustments should be made according to clinical response. Use: Relief of symptoms of depression

Detailed Amtran dosage information


If you overdose Amtran and you don't feel good you should visit your doctor or health care provider immediately. Symptoms of Amtran overdosage: seizures, loss of consciousness for a period of time, seeing things or hearing voices that do not exist, agitation, feeling drowsy, rigid muscles, vomiting, high temperature, cold body temperature, problems concentrating, abnormal heartbeats, confusion.


Store at room temperature between 20 and 25 degrees C (68 and 77 degrees F) away from moisture and heat. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Amtran are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Do not take Amtran if you are allergic to Amtran components. Do not take Amtran if you are pregnant, planning to become pregnant, or are breast-feeding. Be careful with Amtran if you suffer from or have a history of a history of heart attack, stroke, bipolar disorder (manic-depression), schizophrenia or other mental illness, diabetes, overactive thyroid, glaucoma, problems with urination, heart disease, seizures. Be careful with Amtran if you are taking guanethidine (Ismelin), disulfiram (Antabuse), heart rhythm medications such as flecainide (Tambocor), propafenone (Rhythmol), quinidine (Cardioquin, Quinidex, Quinaglute), cimetidine (Tagamet). Avoid alcohol. Be careful! Taking Amtran you can become suicidal. Be careful when you are driving or operating machinery. Be careful with Amtran if you are going to have a surgery. It can be dangerous to stop Amtran taking suddenly.

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The extract had a high phenolic content and strong antioxidative activity, compared with green tea, rooibos tea, and red wine. Sympathetic mediation of induced and spontaneous activity of the pelvis-ureter in vitro. Finally, the relationship between anticipation and pain perception was mediated by anxiety. Under these circumstances the expected net proton consumption caused by ferrocyanide oxidation was preceded by transient acidification. MAPK phosphatase DUSP16/MKP-7, a candidate tumor suppressor for chromosome region 12p12-13, reduces BCR-ABL-induced transformation. Rats received rIL-2 or vehicle either one time only or 3 times daily for 3 days. Effect of feeding safflower oil and coconut oil in experimental myocardial infarction induced by isoproterenol in rats was studied. Knowledge-related educational inequalities were lower in Russia compared to Finland, while they were of similar magnitude in Estonia and Finland. Likewise, no inhibition of lectin dependent cellular cytotoxicity by teniposide and its diluent was observed, suggesting that the lectin may substitute the missing lytic signal. Long-term azathioprine in rheumatoid arthritis: a double-blind study.

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