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Aripicon

Aripicon is used as a treatment for schizophrenia and bipolar I disorder and as an add-on medication for depression. It can also be used to treat children with Tourette syndrome or autism-related irritability.

Other names for this medication:
Apicord, Aridus, Arifril, Arilan, Arinex, Aripat, Aripicon, Aripiprazole, Aripra, Arpicin, Asprito, Biliff, Elrip, Pipra, Rizotal, Schizopra

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Also known as: Aripiprazole

Description

Aripiprazole is used alone or together with other medicines to treat mental conditions such as bipolar I disorder (manic-depressive illness), major depressive disorder, and schizophrenia. It is also used in children to treat irritability associated with autistic disorder and Tourette syndrome. Aripiprazole works in the brain to change how certain chemicals affect patients. It is an antipsychotic agent.

This medicine is available only with your doctor's prescription. {name}® oral solution was withdrawn from the market on May 15, 2015 and this dose form is not marketed by any generic manufacturers.

Dosage

This section provides information on the proper use of a number of products that contain aripiprazole. It may not be specific to Aripicon Mycite. Please read with care.

Take this medicine exactly as directed by your doctor. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered. To do so may increase the chance of side effects.

This medicine should come with a Medication Guide. Read and follow the instructions carefully. Ask your doctor if you have any questions.

If you are using the orally disintegrating tablet, make sure your hands are dry before you handle the tablet. Do not open the blister pack that contains the tablet until you are ready to take it. Remove the tablet from the blister pack by peeling back the foil, then taking the tablet out. Do not push the tablet through the foil. Do not break or split the tablet. Place the tablet in your mouth. It should melt quickly. After the tablet has melted, you may swallow or take a sip of water.

Swallow the tablets whole. Do not break, crush, or chew them.

Aripicon Mycite® has a sensor in the tablet, which helps track it inside the stomach or bowels. The Aripicon Mycite® System comes with a patch (wearable sensor), a smartphone application (app), and a web-based portal. Follow your doctor's instructions on how to use the medicine.

The Aripicon Mycite® tablet is usually detected within 30 minutes after you take it, but there may be a delay of more than 2 hours for the smartphone app and web portal to detect that you have taken the medicine, and sometimes it might not be detected at all.

To apply the Aripicon Mycite® patch:

The app will tell you when to apply or remove the patch. It should be changed weekly or sooner as needed. Place the patch to the left side of your body just above the lower edge of your rib cage. Do not put the patch in areas where the skin is scraped, cracked, inflamed, or irritated, or near the area where you had removed the previous patch. The app will help you place the patch in the correct location. You may keep the patch on when showering, swimming, or exercising.

Aripiprazole may be taken with or without food. If your doctor tells you to take it a certain way, follow your doctor's instructions.

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For oral dosage forms (tablets and orally disintegrating tablets): For bipolar mania: Aripicon® and Aripicon Discmelt®: Adults—At first, 15 milligrams (mg) once a day. When it is given with lithium or valproate, the starting dose is 10 to 15 mg once a day. Your doctor may adjust your dose as needed. However, the dose is usually not more than 30 mg per day. Children 10 years of age and older—At first, 2 mg once a day. The dose will be gradually increased to 10 mg once a day. Your doctor may adjust your dose again as needed. However, the dose is usually not more than 30 mg per day. Children younger than 10 years of age—Use and dose must be determined by your doctor. Aripicon Mycite®: Adults—At first, 15 milligrams (mg) once a day. When it is given with lithium or valproate, the starting dose is 10 to 15 mg once a day. Your doctor may adjust your dose as needed. However, the dose is usually not more than 30 mg per day. Children—Use and dose must be determined by your doctor. For depression: Adults—At first, 2 to 5 milligrams (mg) once a day. Your doctor may adjust your dose as needed. However, the dose is usually not more than 15 mg per day. Children—Use and dose must be determined by your doctor. For irritability in children with autistic disorder: Children 6 to 17 years of age—At first, 2 milligrams (mg) once a day. Your doctor may adjust your dose as needed. However, the dose is usually not more than 15 mg per day. Children younger than 6 years of age—Use and dose must be determined by your doctor. For schizophrenia: Aripicon® and Aripicon Discmelt®: Adults—At first, 10 to 15 milligrams (mg) once a day. Your doctor may adjust your dose as needed. However, the dose is usually not more than 30 mg per day. Children 13 to 17 years of age—At first, 2 mg once a day. The dose will be gradually increased to 10 mg once a day. Your doctor may adjust your dose again as needed. However, the dose is usually not more than 30 mg per day. Children younger than 13 years of age—Use and dose must be determined by your doctor. Aripicon Mycite®: Adults—At first, 10 to 15 milligrams (mg) once a day. Your doctor may adjust your dose as needed. However, the dose is usually not more than 30 mg per day. Children—Use and dose must be determined by your doctor. For Tourette's disorder: Children 6 to 18 years of age—At first, 2 milligrams (mg) once a day. Your doctor may adjust your dose as needed. However, the dose is usually not more than 20 mg per day. Children younger than 6 years of age—Use and dose must be determined by your doctor.

Overdose

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Overdose symptoms may include drowsiness, vomiting, aggression, confusion, tremors, fast or slow heart rate, seizure (convulsions), weak or shallow breathing, or fainting.

Storage

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Detailed Aripicon MyCite dosage information

Side effects

The most common side effects associated with Aripicon are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Appropriate studies have not been performed on the relationship of age to the effects of aripiprazole in children younger than 13 years of age with schizophrenia and in children younger than 10 years of age with bipolar disorder. Safety and efficacy have not been established.

Appropriate studies have not been performed on the relationship of age to the effects of Aripicon Mycite® in children. Safety and efficacy have not been established.

Aripiprazole is not approved for use in children or teenagers with major depression.

Appropriate studies performed to date have not demonstrated pediatric-specific problems that would limit the usefulness of aripiprazole in children 6 to 17 years of age with autistic disorder.

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In nine patients with prior cardiac surgery, defibrillator implantation was performed by a transvenous/subcutaneous approach. Selected ML models offer promise for classifying HF patients (including the gray zone), when driven by ventricular volume data. Maternal hydration increases AFI in women with normal and decreased amniotic fluid, but the increase in AFI lasts for less than 24 h. However, in general, SCF was not sufficient to induce significant changes in obesity-related parameters compared with placebo. An indirect immunofluorescence study of antibodies to Aspergillus funigatus in sera from children and adults without aspergillosis. Ruthenium red bound strongly to elements of the zona and increased the opacity of the plasmalemma. Fusion anomalies of the epididymis with the testis may be clinically relevant in horses. This optimized protein-knockout system offers a powerful and versatile proteomic tool to dissect diverse functional properties of cellular proteins in somatic cells. Before in vivo implantation, these matrices must be efficiently decellularized, removing all the cellular components to avoid any immunogenic reaction. Small cell carcinoma of the uterine cervix: a case report and literature review.

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Reference data on gains in weight and length during the first two years of life. Thus, the present study indicates that the diuretic effects of S-8666 varies with its administration time. This paper explores these differences in relation to the potential for both quantitative and qualitative differences that exist in the nature of sleepiness between non-pathological and pathological sleepiness states. Four medicinal plants (Chrozophora hierosolymitana Spreng, Chrysanthemum leucanthemum L., Ephedra gerardiana Wall. Subsequent fertilization of these oocytes will result in the generation of embryos in which the expression of the gene of interest is downregulated, and following the degradation of maternal proteins the role of the gene product can be levaquin brand or generic studied. The effect of various modalities on maintaining a high intragastric pH in acutely ill patients was evaluated. Age, hemoglobin (Hb) level, systolic blood pressure (BP), Glasgow Coma Scale (GCS) score, timing of and necessity for intubation were analyzed in relation to mortality and in comparison with younger patients. Study of drug-resistant spontaneous mutation in hepatitis B virus gene. Enzymatically Active Microgels from Self-Assembling Protein Nanofibrils for Microflow Chemistry. Differences are also observed in the nitrous acid degradation products of the heparan sulfates.

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It is also suggested that acidosis may motrin dosage chart by weight interfere with vitamin D metabolism and thus play an important role in the pathoetiology of the growth failure in children with this disorder. The problem of cimetidine therapy starts when it is used for almost any gastrointestinal condition in a knee jerk fashion. In this framework, we predicted an increase in speech muscle activity during rumination as compared to rest. Reduction and reoxidation of turkey ovomucoid--a protein with dual and independent inhibitory activity against trypsin and alpha-chymotrypsin. Increased autophagy contributes to cocaine-mediated activation of microglia since pretreatment of cells with wortmannin resulted in decreased expression and release of inflammatory factors (TNF, IL1B, IL6, and CCL2) in microglial cells. However, Rab3D immunostaining was not observed on the plasma membrane and appeared to reside in the apical cytoplasm.

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Complete genome sequence of Cronobacter sakazakii bacteriophage CR3. The original concept of the specially trained flight nurse was first enunciated in 1932, but it was not until 1943 that the first group of such nurses graduated from training for U.S. He discusses how the new categories and nomenclature of the third edition of the Diagnostic and Statistical Manual of Mental Disorders were handled, particularly since clinicians throughout the world have been accustomed to the terminology of DSM-II. Rather, preexisting deficits in social resources might indirectly affect longer-term posttraumatic stress and general psychological distress by increasing risk for disaster-related stressors. The proliferation of ECV was inhibited significantly by celastrol with IC(50) being 1.33 microg/ml. However, there have been at least 2 evolutionary changes in the activation of the MAPK pathway during spiralian evolution.

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