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Armotraz (Anastrozole)
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Armotraz

Armotraz is used to treat breast cancer in women after menopause. Some breast cancers are made to grow faster by a natural hormone called estrogen. Armotraz decreases the amount of estrogen the body makes and helps to slow or reverse the growth of these breast cancers.

Other names for this medication:
Altraz, Altrol, Anabrez, Anastrocare, Anastrozole, Anatero, Anazol, Armilon, Armotraz, Femistra, Femitraz, Qubol, Redest, Rimidex, Stazonex, Xenosoul

Similar Products:
Allegra, Valtrex, Medrol, Diflucan, Zanaflex, Amoxil, Lozol, Tricor, Inderal

Also known as: Anastrozole

Description

Generic Armotraz is brand name for anastrozole, an oral antiestrogen. Generic Armotraz inhibits the enzyme aromatase in the adrenal glands that produces the estrogens (estradiol and estrone) and thereby lowers their levels. Generic name of Generic Armotraz is Anastrozole. Armotraz is also known as Anastrozole. Brand name of Generic Armotraz is Armotraz.

Dosage

The following information describes Armotraz dosages that are commonly used or recommended. However, be sure to take the dosage your doctor prescribes for you. Your doctor will determine the best dosage to fit your needs.

Drug forms and strengths

Armotraz comes as 1-mg tablets that are taken by mouth.

Dosage for breast cancer

The usual dosage of Armotraz for breast cancer is one tablet taken once a day. It’s best to take your dose at the same time each day.

What if I miss a dose?

If you forget to take a dose of Armotraz, take the missed dose as soon as you remember. However, if it’s almost time for your next dose, just skip the missed dose and take your next dose as usual. Don’t take two doses together to make up for a missed dose.

To help make sure that you don’t miss a dose, try setting a reminder on your phone. A medication timer may be useful, too.

Will I need to use this drug long term?

Armotraz is meant to be used as a long-term treatment for breast cancer. If you and your doctor determine that Armotraz is safe and effective for you, you’ll likely take it long term.

The length of time that you’ll take this drug depends on the type of cancer you’re using it to treat. Below we describe the typical length of time that Armotraz is given. But to know for sure how long you should take Armotraz, talk with your doctor.

For advanced breast cancer

If you’re taking Armotraz to treat advanced breast cancer, you’ll usually take the drug for as long as your doctor feels this treatment is right for you. (With advanced breast cancer, the cancer has either spread to nearby areas or lymph nodes, called locally advanced breast cancer, or spread to other parts of your body, called metastatic breast cancer.)

For early breast cancer

If you’re taking Armotraz as adjuvant treatment of early breast cancer, you’ll usually take the drug for at least 5 years. Adjuvant treatment is used to lower the risk of your breast cancer coming back or spreading after it’s already been treated with surgery. (With early breast cancer, the cancer hasn’t spread out of either your breast or the lymph nodes in your armpit.)

It’s not currently known if Armotraz should be continued after these 5 years. And if so, it’s not known for how long after the first 5 years it should be taken.

Some studies found that breast cancer is less likely to come back if an aromatase inhibitor is taken for an additional 5 years after the first 5 years of adjuvant therapy. (Aromatase inhibitors are a class of medications.) With this approach to treatment, the drug would be taken for a total of 10 years. However, other studies didn’t show a benefit for extending the treatment beyond 5 the usual years.

In addition, one recent study found that taking Armotraz for a total of 10 years didn’t provide any more benefit than taking it for a total of 7 years.

How long you take Armotraz for early breast cancer will depend on how likely your breast cancer is to come back. It will also depend on your risk of side effects from treatment.

Overdose

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Storage

Store between 20 and 25 degrees C (68 and 77 degrees F) away from moisture and heat. Throw away any unused medicine after the expiration date. Keep out of the reach of children in a container that small children cannot open.

Side effects

The most common side effects associated with Armotraz are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

You should not use Armotraz if you are allergic to anastrozole, or if you have not yet completed menopause.

Armotraz is not approved for use in men or children.

You should not take anastrozole if you also take tamoxifen.

To make sure this medicine is safe for you, tell your doctor if you have ever had:

heart problems; coronary artery disease (clogged artery disease); high cholesterol; or osteoporosis or low bone mineral density.

Hormonal cancer treatment can weaken your bones. You may be more likely to have a broken bone while using Armotraz. Talk with your doctor about ways to keep your bones healthy.

Although it is not likely that a postmenopausal woman would be pregnant, anastrozole may harm an unborn baby. You may need to have a negative pregnancy test before starting this treatment. Use effective birth control if you are not past menopause. Keep using birth control for at least 3 weeks after your last dose of Armotraz. Tell your doctor if you become pregnant.

Do not breastfeed while using this medicine, and for at least 2 weeks after your last dose.

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Response of the cholesterol metabolism to a negative energy balance in dairy cows depends on the lactational stage. Dark reactivation of ultraviolet-irradiated tobacco necrosis virus. Comparison of cardiac resynchronization therapy outcomes in patients with New York Heart Association functional class I/II versus III/IV heart failure. PCC6803, the circadian clock is assumed to function similarly, yet appears to control transcription to a far lesser extent and its circadian rhythm was reported to not be sustained, or at least rapidly damped, under continuous illumination. Intrathecal humoral immune reaction in 26 patients with a reactivation of varicella-zoster virus was analyzed. When conidia were germinated in media supporting a fast growth rate, the radioactive pulse labeled either all of the nuclei in a cell or none of them. Importantly, the latter allowed for the first time to directly extract the true shape of HRF without any assumption and probe neurovascular coupling, using performance-matched stimuli.

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Long-term therapy with a branched-chain amino-acid-enriched elemental diet. Influence of intra-arterial insufflation of gas on the peripheral circulation and its dangers. Twenty-one cerebrospinal fluid samples from newborns ranging from 25 to 40 weeks of gestation were similarly determined. Antibody binding was inhibited by ganglioside fractions derived from chicken and mammalian brains. We assessed chromosomal stability through karyotype analysis, determined whether multipotent capacity (differentiation into adipogenic, chondrogenic, and osteogenic cells) is maintained, and analyzed SOX2 and NANOG expression after thawing. One is the already known unstable Guo-AF (and respectively dGuo-AF) (1). The methodology of determining an invisible target by CT-stereotaxy, such as the ventrolateral nucleus of the thalamus, is described. These considerations should be part of the routine before therapy is being initiated. A Single Aspiration of Rod-like Carbon Nanotubes Induces Asbestos-like Pulmonary Inflammation Mediated in Part by the IL-1 Receptor.

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B cell depletion before helper cell induction increased the efficiency of helper cell induction and thus provided further proof of the T-cell nature of in vitro helper cells. Plasma LH concentrations were decreased by progesterone treatment (P less than 0.025) and increased by ovariectomy (P less than 0.001). Rather c-ets-1 transcripts are abundant in the dermal cells which divide and accumulate under the uniform epidermis. The OspC gene was amplified from the genome of Borrelia burgdorferi PD91 strain by polymerase chain reaction and recombined with plasmid PET-11D. The leukoderma may be hypomelanotic and mottled or depigmented and milk-white. Since there is considerable disagreement in grading cytoplasmic haloes, this prospective study was set up to evaluate if certain subtypes of haloes are related to further development. Here we show that extinction of bioactive LWamides from planulae causes loss of metamorphosis competence, a deficiency which can be rescued by synthetic LWamide peptides.

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To determine whether puromycin had caused the release of ribosomes, sections from puromycin-treated cells were stained nonspecifically with uranyl acetate. Development of Consensus-Based Best Practice Guidelines for Postoperative Care Following Posterior Spinal Fusion for Adolescent Idiopathic Scoliosis. A modified procedure for the preparation of UDP-beta-L-(U-14C)rhamnose. A general method for the isolation of non-sense suppressor strains in gram-negative bacteria. Predicting Attitudes toward Press- and Speech Freedom across the U.S.A.: A Test of Climato-Economic, Parasite Stress, and Life History Theories. It is important to understand the integral strengths and weaknesses between the different modalities of stress testing and to apply accurately the type of test the clinical scenario demands. Thymosin beta 3 was detected almost exclusively in cells covering the cortical surface.

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Aspartate aminotransferase immunoreactivity in cochlea of guinea pig. Fibrosis of the kidney is a disease affecting millions worldwide and is a harbinger of progressive loss of organ function resulting in organ failure. Intersectoral action to manage and prevent obesity is urgently required to reverse current trends. PROMIS is an efficient clinical assessment platform for measuring patient-reported outcomes in PHPT via CAT. have now provided evidence for correlated remodelling of presynaptic structures. Centrifugation of comminuted, infected mosquitoes applied to the top of the discontinuous gradient concentrates sporozoites at the interface. This increase in mobility depends on the size and number of removed carbohydrate chains. Another group of pigeons had similar training, except that a low rate of key-pecking was established in a stimulus with a much higher frequency of food reinforcement. Bacterial antigen and acid phosphatase in macrophages in experimental pyelonephritis. Metastatic breast cancer to the rectum: A case report with emphasis on MRI features.

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We report a complication of double lumen hemocatheter guide wire entrapment in a 43-year-old female of type 1 diabetes mellitus and hemodialysis patient. All patients were from 12 renal clinics at tertiary-care university hospitals. Surgical quality surveillance and sustaining improvement by surgical team could further reduce postoperative hospital stay and perioperative complications. Seed/Catalyst-Free Growth of Gallium-Based Compound Materials on Graphene on Insulator by Electrochemical Deposition at Room Temperature. Modification by ferrocene: An approach to enhance antioxidant ability of ailanthoidol to protect DNA. Therefore, we propose that saccharic acid could serve as a lead compound for the development of potent and selective inhibitors of bacterial hyaluronan lyase or of polysaccharide lyase enzymes in general as we observed this compound to be capable of inhibiting chondroitinase ABC in addition to hyaluronan lyase. This analysis was based on the calculation of the position of centroids in the multidimensional space described by the linear functions of the chosen parameters for each of the evaluated bone section areas. Principles of ulterior obstetrical prognosis of extra-uterine pregnancies. To help prevent such episodes, rapid detection of these fishes in the supply chain of the seafood industry and by food and health inspection agencies is essential. This difference may be attributed to a greater number of stapled anastomoses performed in the laparoscopic cohort.

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In critical illness, the gut is susceptible to hypoperfusion and hypoxia. Rac1 regulates sepsis-induced formation of platelet-derived microparticles and thrombin generation. Statistical analysis was done by calculating univariate differences in blood pressure between cases with and without complications. The intrinsic DNA binding constant (Kb) of both compounds were evaluated via UV-Vis spectrophotometry. To control the epidemic, public health officials initiated enhanced surveillance, isolation of SARS patients, use of personal protective equipment (PPE) by health-care workers, and quarantine of contacts of known SARS patients. The results suggest patients with aMCI showed impaired encoding and recognition functions during the visuospatial working memory task, and may pay more effort to maintain the cognitive state.

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Hospice teams may benefit from further education and training to help cross the schism of family-centered hospice care as a clinical ideal to one where hospice team members can fully support and empower family caregivers as a hospice team member. It seems likely that discontinuation events can be particularly severe when combinations of different types of antihypertensive medications are sud-disease when betablocker treatment is denly stopped. DCL4 imposed an epistatic effect on DCL2 to impede cell-to-cell spread of VIGS. None of the subjects showed improved speech recognition scores when variations in quadratic curvature were compressed in addition to level and slope compression. We show that health care financing also has a bearing on the political implementability of optimal health care policies.

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In all cases, fluorescence intensity differences were caused by impaired dye accumulation, and could be eliminated by treatment of P388/ADR cells with verapamil. So far none of the antifibrotic substances such as proline analogues, colchicine, lathyrogens and penicillamine has been used in longer-term antifibrotic treatment. 3-Methyladenine DNA glycosylase II (AlkA) is an enzyme that cleaves a wide range of damaged bases from DNA. The motile behaviors of growth cones at the ends of elongating axons determine pathways of axonal connections in developing nervous systems. Blocks of greater depth and longer duration result from injection of smaller volumes and, correspondingly, higher lidocaine concentrations containing the same dose. In this analysis we examine the relationship between nonresidential father involvement with their children and adolescent smoking behavior using a nationally representative longitudinal dataset. Both generalized structural equation model and MacArthur approach were used to examine their intrinsic relationships. The pathophysiology of bipolar disorder is likely to involve both genetic and environmental risk factors.

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The study was part of a larger trial comparing four different NRTs. beta2 microglobulin is a plasma protein of low molecular weight (11800), which also appears in urine in small quantities and cerebrospinal fluid. Thereafter, the patient underwent pulsed radiofrequency treatment to bilateral greater occipital nerves. Mutagenicity of chemicals of industry and agricultural relevance in Salmonella, Streptomyces and Aspergillus. Clinical studies on occlusion of the retinal artery by fluorescein fundus photography. The aim of this review is to evaluate some of the available monitoring systems and summarize recent important data showing the clinical utility of multimodal neuromonitoring for the management of main acute neurosurgical conditions what medication is like celexa , including traumatic brain injury, subarachnoid hemorrhage and stroke. Salicylate blockade of granulocyte adherence and the inflammatory response to experimental peritonitis. Timolol given on a twice-daily schedule has shown both antihypertensive effectiveness and plasma-renin-suppressing action in different subject. Thus, we recommend the optimal liver-specific expression system for safe and effective transfection of pig cells.

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Assay of E and EAC rosette forming peripheral lymphocytes in human bancroftian filariasis. Plasmids that contained mutations in the amino-terminal dnaJ domain of the early region fail to transform human diploid fibroblasts. The mycological and histological examinations are fundamental to confirm the diagnosis. Reducing dietary saturated fat and excess body weight may be useful means of improving glycaemic control in older adults with diabetes. Marked preservation of the visual and olfactory pathways in ALS patients in a totally locked-in state. Blockade of beta-adrenergic receptors reduced GH and increased LH values. However, there seems to be a difference between strains with single and diffuse adult hemoglobin in the time of emergence of a clear adult pattern. The present study was designed with an objective to assess the inhibition of lipid peroxidation (LPO) by the aqueous extract of Calocybe indica (milky mushroom) using an invitro model of goat liver homogenate and RBC ghosts. Long-term EEG monitoring in uremic children on chronic dialysis treatment.

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Real-time PCR analysis showed different melting temperatures of the amplified fragment containing normal allele and that harboring the 18 bp deletion, thus providing a rapid screening assay for this and other deletions of the TCOF1 gene. Three-hundred and twelve patients with previously untreated clinical T2-4 gastric cancer who underwent a D2 standard gastrectomy (distal gastrectomy or total gastrectomy) were included in the analysis. Twenty hypertensive patients treated by psychophysical relaxation exercises were followed up monthly for 12 months. Biochemical determinations were made in blood and 24-hour urine. However, endogenous NO amount sharply decreased at experimental acute renal failure. This drawback may be addressed through improvements in the collection of SHG signals via an epi-illumination microscope configuration. Clinical utility of Wechsler Memory Scale-Revised and predicted IQ discrepancies in closed head injury. INHIBITION OF BIOLOGICAL SYNTHESIS OF ACETYLCHOLINE BY TRIETHYLCHOLINE. CHEMICAL AND BIOLOGIC APPROACHES TO THE THERAPY OF VIRAL DISEASES. Furthermore, rationale combination therapies incorporating currently approved mRCC-targeted therapies should be explored as these approaches hold the greatest potential for translating OVs into the clinical arena for use against this disease.

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