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Ascool (Labetalol)
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Ascool

Ascool is used to help lower blood pressure. It's often used with other blood pressure-lowering medications. Ascool is an alpha and beta blocker medication. It lowers blood pressure by relaxing blood vessels (by blocking alpha receptors) and slowing heart rate (by blocking beta receptors).

Other names for this medication:
Albetol, Ascool, Biascor, Hybloc, Ibidomide, Ipolab, Labetalol, Labetaloli, Labetalolo, Labetalolum, Normadate, Normodyne, Normozide, Presolol, Resporito

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Also known as: Labetalol

Description

Labetalol injection is used to treat severe high blood pressure (hypertension). High blood pressure adds to the workload of the heart and arteries. If it continues for a long time, the heart and arteries may not function properly. This can damage the blood vessels of the brain, heart, and kidneys, resulting in a stroke, heart failure, or kidney failure. High blood pressure may also increase the risk of heart attacks. These problems may be less likely to occur if blood pressure is controlled .

This medicine is a beta-blocker. It works by affecting the response to nerve impulses in certain parts of the body, like the heart. As a result, the heart beats slower and decreases the blood pressure. When the blood pressure is lowered, the amount of blood and oxygen is increased to the heart .

This medicine is available only with your doctor's prescription .

Dosage

This section provides information on the proper use of a number of products that contain labetalol. It may not be specific to Ascool. Please read with care.

A nurse or other trained health professional will give you this medicine. This medicine is given through a needle placed in one of your veins .

Detailed Ascool dosage information

Overdose

If you overdose Ascool and you don't feel good you should visit your doctor or health care provider immediately.

Storage

Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) away from moisture, light and heat. Keep container tightly closed. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Ascool are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

You should not use Ascool if you are allergic to it, or if you have:

asthma; "AV block" (2nd or 3rd degree); uncontrolled heart failure; very low blood pressure; slow heartbeats that have caused you to faint; or if your heart cannot pump blood properly.

Tell your doctor if you have ever had:

congestive heart failure; angina (chest pain); liver disease; emphysema, chronic bronchitis, or other breathing problems; pheochromocytoma (tumor of the adrenal gland); diabetes; coronary artery bypass surgery (sometimes called "CABG"); kidney disease; or allergies.

Ascool can affect your pupils. If you need eye surgery, tell the surgeon about your use of Ascool, even if you no longer take it.

Ascool may cause low blood pressure, low blood sugar, slow heartbeats, or breathing problems in a newborn if the mother uses this medicine during pregnancy. Tell your doctor if you are pregnant or plan to become pregnant.

Ask a doctor if it is safe to breastfeed while using this medicine.

Not approved for use by anyone younger than 18 years old.

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Reduction of in vivo striatal 5-hydroxytryptamine release by 8-OH-DPAT after inactivation of Gi/G(o) proteins in dorsal raphe nucleus. There were no differences in SCBF or cord water content between the MK801 and saline groups. Here we demonstrate that Tyro3 subfamily of receptor tyrosine kinases, Tyro3, Axl, and Mer (TAM), negatively regulate TLR3 signaling in Sertoli cells. In vivo cultivation of leukocytes in diffusion chambers: requirement of ascorbic acid for differentiation of mononuclear leukocytes to fibroblasts. Supplemental dietary zinc (110-120 microg/g) together with fluoride treatment resulted in complete reversal of the fluoride-mediated effects. Increased prostacyclin (PGI2) via COX-1 and COX-2 overexpression, and increased EETs/heme-oxygenase-1/K channels/gap junctions (endothelial derived hyperpolarizing factor system) play a major role in mesenteric vasodilatation, hyporeactivity to vasoconstrictors, and hyper-response to vasodilators. The polymorphisms of stearoyl-CoA desaturase (SCD1) and sterol regulatory element binding protein-1 (SREBP-1) genes and their association with the fatty acid profile of muscle and subcutaneous fat in Fleckvieh bulls. Basic scientific investigation employing the medical imaging techniques of contrast-enhanced plane film radiographs and computed tomography in addition to gross dissection techniques on a sample of spines. Daidzein enhances efferocytosis via transglutaminase 2 and augmentation of Rac1 activity.

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Silicon carbide microsphere/birnessite-type MnOx (SiC/B-MnOx) composites were prepared by removal of a SiO2 layer with redox deposition of birnessite-type MnOx for supercapacitor electrode materials. Participants were recruited from urban, suburban, and rural communities at 8 centers throughout the United States. Both assays detected pharmacological and neurodevelopmental gene sets regulated by valproic acid. Metrx quadrant system in the surgery of lumbar spondylolisthesis: preliminary clinical application. Signet-ring cell melanoma is a rare morphologic variant of melanoma. Membrane blebbing, the formation of apoptotic bodies and caspase activation, as measured by cleavage of Asp-Glu-Val-Asp (DEVD) substrate and poly(ADP-ribose) polymerase (PARP), indicate that these cells die by an apoptotic process. We therefore speculate that the hormonal difference between sexes might influence salt sensitivity in the SHRSP. Our results demonstrate the preclinical efficacy of using a targeted therapy approach for Group 3 medulloblastomas. Our case-control study showed that the CT genotype was significantly associated with decreased breast cancer risk. The pertinent diaphragmatic attachments to the rib cage are at the 11th and 12th ribs.

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To examine the risk of recurrence of low Apgar score in a subsequent term singleton pregnancy. In this filtering process, strong filters with very low b can be applied to regions distant from the LSF center, and the region near the LSF center can be maintained simultaneously by a correspondingly high b. At the end of a CT scan of the head appeared features of arterial air embolism. We investigated whether risk alleles of single nucleotide polymorphisms associated with intracranial aneurysm (IA) are enriched in patients with familial IA, IA located at the middle cerebral artery (MCA), or IA rupture at a younger age. The purpose of this study was to evaluate whether various technical advancements have affected the outcome of lumbar spinal fusion for degenerative disease by critically analyzing the available literature from the past two decades. The disruption can result in unhealthy exposures and environments and income returns for the origin household.

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Progression and Transformation of Clonally Heterogeneous B-cell Lymphoma. Molecular study clearly demonstrated B-cell lineage with immunoglobulin heavy and kappa light chain gene rearrangements. Further, the size of ultrathin film is typically limited to a few square millimeters. Nutlin-3a induces cytoskeletal rearrangement and inhibits the migration and invasion capacity of p53 wild-type cancer cells. This study investigated the value of lung ultrasonography in diagnosing pediatric necrotizing pneumonia and its role in predicting clinical outcomes. Here we investigate how the flexibility of individual protein chains influences the assembly and evolution of protein complexes. The psychological aspects of burn injury have been researched in different parts of world producing different outcomes. To date, conjugation and transformation have been reported for this organism. Intermittent parathyroid hormone (1-34) enhances mechanical strength and density of new bone after distraction osteogenesis in rats.

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Segmental durations, positions, and interarticulator timing can all be quantitatively evaluated. Here, protocols are presented describing the in vitro assembly of evenly spaced nucleosomal arrays on DNA fragments harboring gene regulatory sequences and the use of these templates with purified HAT complexes in transcription assays. To determine whether a correlation exists between concentrations of intracellular and extracellular potassium and to determine the frequency of ventricular ectopy in patients after cardiac operations. Antagonistic effect of NK4, a novel hepatocyte growth factor variant, on in vitro angiogenesis of human vascular endothelial cells. The present study was carried out to determine effects of test meals of different fatty acid compositions on postprandial lipoprotein and apolipoprotein metabolism. The modern era began with the recognition that patterned behavior, for example, self-injury in Lesch-Nyhan syndrome and hyperphagia in PWS, was syndrome-specific, and when parent support groups pointed out syndrome-specific behavioral similarities in their children. Biochemical and hemocoagulation criteria for evaluating the risk of nephropathy development in workers with occupational exposure to dust.

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Magnetic resonance signal intensities of the anterior cruciate ligament (ACL) and posterior cruciate ligament (PCL) were compared. In 15 patients, we also observed the postpeak decay of plasma virus and found that the virus decay occurred at a median rate of 0.60 day(-1), corresponding to a half-life of 1.2 days. Potential benefits of offering ultrasound examination to low risk patients are explored, including detection of anomalies, diagnosis of multiple gestation, and reduction in induced labors for erroneous diagnoses of postdatism. The results of the present study indicate that ADP-induced platelet aggregation is enhanced in NPC patients of stage III and stage IV. In the introductory part, the authors present several patrons/patronesses of the eyes and sight, as well as the protectors from eye diseases. The Murphy sign and laboratory tests performed independently are also not particularly accurate.

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Sixty-four participants (32 HDS, 32 LDS) were required to make a PM response when target words were presented during an ongoing lexical decision task. The HP-treated oysters cooked in the oyster omelette are acceptable to consumers. The aetiology, diagnosis and treatment of postoperative pulmonary drugs xanax bars complications. While smoking in Norway has become less prevalent, snus use has increased, including among women. In vivo role of complement-interacting domains of herpes simplex virus type 1 glycoprotein gC. Effect of high-dose intravenous immunoglobulin treatment in therapy-resistant chronic spontaneous urticaria.

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Flexor pollicis longus reconstruction using the palmaris longus in anterior interosseus nerve syndrome. To compare the myocardial glucose metabolism of normal subjects to patients with DM, we performed a quantitative FDG study during insulin clamp, oral glucose loading and fasting in nine normal volunteers and eight patients with noninsulin-dependent DM (NIDDM). Clinical features were compared for those with or without substance abuse/dependence histories predating the index manic episode. Generally, the low yield of collagen extracted using the typical acid solubilisation process has led to the use of mammalian pepsin as an aid for increasing the yield. The increase of adult iMN is mainly due to the increase of early stages of iMN in young patients. Implantation of the embryo into the uterine compartment is a multistep event involving attachment of the embryo to the endometrial epithelia, followed by invasion of the embryo through the endometrial stroma. We developed a practical index for capturing health service coverage - a critical dimension of UHC -- that was more inclusive than previous methods. subtilis mutants leads to severe growth defects, inhibitors of the enzyme could form a new family of antibiotic drugs.

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Cutaneous Phaeohyphomycosis Caused by Exophiala attenuata in a Domestic Cat. This study was designed to examine the characteristics of such a sequence for the investigation of orbital mass lesions. Although there is a large toolkit to increase quantification levels for LC-MS/MS, these techniques are sometimes insufficient to attain the needed limits of quantification (LOQs) or the method becomes too impractical for routine use. Experience in the treatment of 730 cases of distortions and contusions of the knee joint without injury of the ligament. Yet, it is unclear whether such a phenomenon may be generalized to musical emotions. Comparison of indirect immunofluorescence on Crithidia luciliae of Farr test, and immunoenzymatic methods for the screening of anti-native DNA autoantibodies.

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