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Asicom (Clopidogrel)
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Asicom

Asicom is in a class of medications called antiplatelet medications. It works by preventing platelets from collecting and forming clots that may cause a heart attack or stroke. Asicom is used alone or with aspirin to prevent serious or life-threatening problems with the heart and blood vessels in people who have had a stroke, heart attack, or severe chest pain.

Other names for this medication:
Antiban, Antiplar, Aplatin, Asogrel, Atormac, Blothin, Carpigrel, Cenoza, Ceruvin, Clasprin, Clofre, Clopact, Clopicure, Clopidogrel, Clopiget, Clopigrel, Clopione, Clopiriv, Clopisa, Clopiwa, Cloplat, Clospir, Compivas, Complatt, Deplatt, Ecosprin, Kabitrol, Myogrel, Noklot, Noplaq, Nugrel, Themigril, Vivosprin, Welgrel, Zoclop, Zogrell

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Also known as: Clopidogrel

Description

{name} (clopidogrel) prevents platelets in your blood from sticking together to form an unwanted blood clot that could block an artery.

{name} is used to lower your risk of having a stroke, blood clot, or serious heart problem after you've had a heart attack, severe chest pain (angina), or circulation problems.

Dosage

Take Asicom at the same time every day, with or without food. Take Asicom tablets orally with water. If you want to achieve most effective results do not stop taking Asicom suddenly.

Overdose

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. Overdose can cause excessive bleeding.

Storage

Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) away from moisture and heat. Throw away any unused medicine after the expiration date. Keep out of the reach of children in a container that small children cannot open.

Side effects

The most common side effects associated with Asicom are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Do not take Asicom if you are allergic to Asicom components. Do not take Asicom if you're pregnant or you plan to have a baby, or you are a nursing mother. Be careful with Asicom if you suffer from or have a history of stroke, stomach ulcer or ulcerative colitis; liver or kidney disease, hemophilia. Be careful with Asicom if you are taking such medicines as aspirin or other NSAIDs (non-steroidal anti-inflammatory drugs such as naproxen (Aleve, Naprosyn), diclofenac (Voltaren), diflunisal (Dolobid), etodolac (Lodine), flurbiprofen (Ansaid), indomethacin (Indocin), ibuprofen (Motrin, Advil), (Toradol), ketoprofen (Orudis), nabumetone (Relafen), piroxicam (Feldene), ketorolac mefenamic acid (Ponstel), meloxicam (Mobic) and the others), phenytoin (such as Dilantin); torsemide (such as Demadex); medication used to prevent blood clots (alteplase (such as Activase), anistreplase (such as Eminase), dipyridamole (such as Persantine), streptokinase (such as Kabikinase, Streptase), ticlopidine (Ticlid) and urokinase (such as Abbokinase); fluvastatin (such as Lescol); a blood thinner (warfarin (such as Coumadin), heparin, ardeparin (such as Normiflo), dalteparin (such as Fragmin), danaparoid (such as Orgaran), enoxaparin (such as Lovenox), or tinzaparin (such as Innohep); tamoxifen (such as Nolvadex); tolbutamide (such as Orinase). It is not recommended to do sport while taking Asicom because it can cause bleeding or bruising injury. If you are going to have a surgery you should stop taking Asicom for 5 days before the surgery. Do not use potassium supplements or salt substitutes. If you want to achieve most effective results without any side effects it is better to avoid alcohol. Do not stop taking Asicom suddenly.

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In the light of a case of cancer on a kidney transplant, in a series of 729 consecutive renal transplantations performed between January 1987 and December 2000, the authors discuss the epidemiology, pathophysiology, prognosis, treatment and prevention of this disease and emphasize the importance of regular and prolonged periodic ultrasound surveillance of kidney transplants. Multivariate analysis showed that stage of disease, performance status, histology and TPS were the most important prognostic factors. Genomic studies have shown that breast cancer includes a large number of targetable genomic alterations. Studies with a neutralizing antibody against Xenopus MAP kinase kinase (MAPKK), a direct upstream activator for MAP kinase, have shown that the MAP kinase cascade plays a crucial role in both initiating oocyte maturation and inducing metaphase arrest. The p.Trp719Arg SNP in the kinesin-like family 6 (KIF6) gene has recently been reported as a potential risk factor for CAD as well as a predictor of response to statin therapy. The surgical management of primary and metastatic Merkel cell carcinoma. Together, these results allow us to describe the biomechanical principles underlying substrate boring in parasitoid ichneumonid wasps. To determine the utility of the technetium-labeled autologous white cell scintigraphy (Tc-WCS) for detecting intestinal inflammation in children with suspected inflammatory bowel disease (IBD). At its simplest a model may consist of little more than a secondary structure prediction coupled with a determination of the likely regions of transmembrane/membrane surface/globular configuration. A total of 24 RAHs were recognised in 20 patients: 7 arose from the A1, 5 from the anterior cerebral artery (ACA)-anterior communicating artery (Acom), 11 from the A2, whereas in 1 case, the segment of origin from the ACA could not be identified.

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It is shown that such technique also enables the determination of the density as a function of pressure for liquids, of the complete set of elastic constants for single crystals, and of the melting curve for any kind of material. Deviations of Wechsler-Bellevue subtest scores from vocabulary level in superior adults. Mouse models could potentially provide new insights into this disease, although primary human MDS cells grow poorly in xenografted mice. Cutaneous Immune Defenses Against Staphylococcus aureus Infections. During human meiosis, SMC5/6 is located at the synaptonemal complex (SC), the XY body, and at the centromeres during meiotic metaphases.

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Using a fixed-dose analysis and an isobolographic paradigm, the spinal interaction between the alpha 2-adrenoceptor agonist clonidine and the N-methyl-D-aspartate antagonist MK-801 is characterized in a rat model of nerve injury-induced tactile hyperesthesia. The drug also impaired inhibitory avoidance acquisition in the elevated T-maze, indicating an anxiolytic effect, without affecting escape performance. The amount of adsorbed Pluronic on hydrophobic polymer surfaces (PP, PET, and nylon) exceeds that on the hydrophilic cellulose. Such groupings can help develop a practical approach in evaluating diseases of the central airways. There was a dramatic resolution of the cerebral lesions with tapering of immunosuppression and introduction of rituximab treatment. Effect of some sulfhydryl-containing substances on the toxicity of an organic mercurial compound. Bacteriuria in children with neurogenic bladder treated with intermittent catheterization: natural history. The considerable exposure to chemicals, time course and unusual pattern of organ involvement suggested a diagnosis of occupational scleroderma. Involvement of neutrophils and natural killer cells in the anti-tumor activity of alemtuzumab in xenograft tumor models.

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Serodiagnosis and seroepidemiology of human unilocular hydatidosis in Jordan. Meticulous case selection for ESD novice and active supervision by expert endoscopists during the initial learning period may minimize the risk of perforation. Changes in the activity of blood thrombokinase in patients with malignant neoplasms under the influence of radiotherapy. High quality controlled studies investigating relevant long term outcome measures are needed to address the question of the best form of iodine supplementation in different population groups and settings. Grade 3, reversible ototoxicity was the DLT in less-heavily pretreated patients at 420 mg/m(2). In the presence of AMF radiocesium uptake decreased regardless of the concentration of K, and its translocation from root to shoot was also significantly lower. Dysregulated IL-1/NO cross-regulation may play a role in inflammatory diseases. Secondary amyloidosis occurs in patients with chronic infectious or inflammatory processes.

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Human chymase is a potent and specific angiotensin (Ang) II-forming serine proteinase. Exosomes secreted from CMs are internalized by fibroblasts and regulate gene expression in these cells as well as in ECs. These abnormalities disappeared early after the discontinuation of oral procainamide. Anomalous Hanle effect due to optically created transverse overhauser field in single InAs/GaAs quantum dots. We could not diagnose the case as X-linked juvenile retinoschisis because there was no family history of it, central foveal reflex was observed in right eye with corrected visual acuity of 1.2, and no abnormality was recorded in the electroretinogram. Long-term randomized controlled trials of tailored-print and small-group arthritis self-management interventions. This may be clinically relevant, particularly for hospital administrators, given the improvement in meeting national WT standards we found post-intervention. They often cause the malnutrition problems and social isolation.

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Analysis of CD39/ATP diphosphohydrolase (ATPDase) expression in endothelial cells, platelets and leukocytes. Factors affecting the incidence of club root disease of brassicae. The bacterial enzyme histidine decarboxylase (Hdc) catalyses the conversion of histidine into histamine. Development and Validation of a Prognostic Nomogram for Progression-Free Survival in Patients with Advanced Renal Cell Carcinoma Treated with Pazopanib. Evaluation of the images was performed by the calculation of the number of metastases by three independent readers and by visual assessment on a 4-point scale. Trials in which patients having resection of colorectal cancer metastatic to the liver were randomised either to hepatic artery chemotherapy or any alternative treatment. The behavioral changes such the sedative effects of alpha 2 agonists and the increased locomotion and CNS excitability seen with some opioids are important considerations when these agents are used as analgesics.

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Bone Density and Fractures in HIV-infected Postmenopausal Women: A Systematic Review. Parasite strain specificity of precursor cytotoxic T cells in individual animals correlates with cross-protection in cattle challenged with Theileria parva. Raw coffee based dietary supplements contain carboxyatractyligenin derivatives inhibiting mitochondrial adenine-nucleotide-translocase. Epidemiological studies of an epidemic of dysentery in a community. Audit can be developed for epilepsies that delivers standardised quality metrics against national recommendations. The P911 variant of the P815 mastocytoma was shown by Lurquin et al. The primary objectives were to compare the duration of sickness absence in employees with high levels of somatic symptom severity (HLSSS) with employees with lower levels of somatic symptom severity, and to establish the long-term outcomes concerning return to work (RTW), disability and discharge. Neural substrates of graphomotor sequence learning: a combined FMRI and kinematic study. It is likely that identification of the full catalog of pathways associated with cilia will be necessary to fully understand their role in regulation of signaling and the implications for diseases associated with their dysfunction, ciliopathies.

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Herein, a TiO2/carbon/Al2O3 membrane was designed and constructed through sequentially depositing graphitic carbon layer with good electro-conductivity and TiO2 nanoparticles layer with photocatalytic activity on Al2O3 membrane support. Case study of the anemic patient: epoetin alfa--focus on protocols. Distal humeral fracture with associated triceps tendon avulsion in a renal transplant recipient. Maximal response was enhanced both in arteries with and without endothelium treated or not with angiotensin II. In rural Bangladesh pregnancies are exposed to similar seasonality. Analysis of the local surface forcing suggests that the 1990s buoyancy forcing has a dynamic effect consistent with altimetric and hydrographic observations: A weak thermohaline forcing allows the decay of the domed structure of subpolar isopycnals and weakening of circulation. The surgeon confronted by the so-called chilled amebic hepatitis and multiple abscess of the liver in South Vietnam.

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A mailed questionnaire including the HAQ, visual analogue scales for pain and global health, comorbidities, education level, height, weight, and smoking status was administered in June 2000. The relationship between the dose of Taiwan cobra (Naja atra) and Taiwan habu (Trimeresurus mucrosquamatus) venom and time of death in mice. Sodium nitroprusside (SNP)-induced RA FLS apoptosis was associated with reduced synoviolin expression and was rescued by IL-17 treatment with a corresponding increase in synoviolin expression. Design, synthesis, and SAR of 2-dialkylamino-4-arylpyrimidines as potent and selective corticotropin-releasing factor(1) (CRF(1)) receptor antagonists. Both of these kinases are activated in cells by phosphorylation of a conserved residue in the kinase domain (Thr-308 of protein kinase B (PKB) and Thr-252 of p70 S6 kinase) and another conserved residue located C-terminal to the kinase domain (Ser-473 of PKB and Thr-412 of p70 S6 kinase). Specifically, a highly enriched signature that harbored H3K4me0, H3K9me2/3, H3K79me0 and H4K20me2/3 within the same nucleosome was identified from chromatin enriched by ATRX-ADD. CYP2C44, a new murine CYP2C that metabolizes arachidonic acid to unique stereospecific products.

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These cases illustrate the importance of detailed inquiry into family medical history and the pleiotropy of the PPB-related familial cancer predisposition syndrome, which appears to result from heterozygous DICER1 mutations. Debris and 1/f noise in sliding friction dynamics under wear conditions. The Acumed system provided limited cancellous bone when used with the technique described. It is not yet certain whether this migration involves myosin or another A band component. Isolation of uridine diphosphate-galacturonic acid from seedlings of Phaseolus aureus. In addition, hypoplastic VAs entered the FT at an anomalous level more often than VAs with normal diameter. Continuous feedback control of Langevin processes may be non-Markovian due to a time lag between the measurement and the control action.

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As far as aPTT values are concerned, there were no significant differences among the three groups. The proposed error signal for saccade adaptation has been based on the distance between where the eye lands and the visual target (retinal error). ASAM Patient Placement Criteria treatment levels: do they correspond to care actually received by homeless substance abusing adults?. There is very little information on the management of delirium in the literature despite an increasing body of information about the incidence, risks and prognosis of the disorder in the elderly population. Intramural hematoma with gastric outlet obstruction: a rare complication of endoscopic injection therapy for bleeding anastomotic ulcer. To correlate RPE during a 6-minute walk test (6MWT) with biological/physiological dilantin loading dose oral measures in subjects with chronic hepatitis C (CH-C) and non-alcoholic fatty liver disease (NAFLD). Current international guidelines recommend first-line treatment of CHB infection with pegylated interferon, entecavir, or tenofovir, but the optimal treatment for an individual patient is controversial. Solid lesions of the body and tail of the pancreas challenge all the diagnostic and technical skills of the modern gastrointestinal surgeon. Adaptive design of confirmatory trials: Advances and challenges.

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We aimed at determining differentially expressed proteins by quantitative proteome analysis in arterial tissue from patients with different degrees of arterial stiffness. This article reviews the use of BMSCs for cardiovascular disease and the differentiation of BMSCs into cardiaomyocytes. temovate brand Enantioselective formation of chiral dihydrobenzofurans and analogues was achieved through a copper-catalyzed desymmetrization strategy with a chiral cyclic 1,2-diamine. Intakes of meat, milk and eggs showed a positive association with serum total cholesterol concentration in both sexes while intake of legumes showed a negative association only in men in both the 1980 and 1990 surveys. We compared the effects of 6 different rotary systems on transportation, canal curvature, centering ratio, surface area, and volumetric changes of curved mesial root canals of mandibular molar via cone-beam computed tomographic (CBCT) imaging. The studies comparing fiberoptic endoscopic evaluation of swallowing and modified barium swallowing have demonstrated that both tests present similar sensitivity, specificity and predictive values. As of March 2004 CNA teams were established in five NHs, and baseline survey data were collected from the CNAs, nurses, residents, and family members in each of these NHs as well as from those in the five comparison homes. We therefore propose that the distribution feature of Hurst exponents of essential genes can be used as a classification index for essential gene prediction in bacteria.

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Cardiovascular disease is the major cause of death in hemodialysis patients. To investigate the expression and localization pattern of LIP5, we studied LIP5 protein expression in a mouse tissue panel and subjected various rodent and human tissues to immunohistochemistry. The presentation of this patient with hypoglycemic coma without preceding symptomatology, to our knowledge, has never been reported. On-resin peptide macrocyclization using thiol-ene click chemistry. To document the development of work participation in young adults with cerebral palsy who are transitioning into adulthood, examine associated characteristics, and investigate work limitations and barriers among employed persons. Haematological study in pulmonary tuberculosis and the effect upon it of large doses of vitamin C.

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A broth microdilution test was carried out following the National Committee for Clinical Laboratory Standards reference method, with modifications described previously. Ulcerative cystitis with an easily bleeding mucosa is a common cystoscopic finding. Report on the teaching and scientific activities of the Scuola di Sanita Militare in the 2-year period, 1960-1961. Simultaneous recordings of TA and CT muscle activity and audio were obtained during production of pitch glides and a variety of midrange and upper pitches in chest, chestmix, headmix, and head registers. We conclude that in human mast cells glucocorticoids effectively and selectively upregulate the expression of 5-LO. Antiplatelet therapy is essential for critical limb ischemia (CLI) patients, both as primary prevention for ischemic events and as adjuvant pharmacotherapy in order to avoid acute or late thrombo-occlusive events and maintain patency following peripheral endovascular or open surgical limb-salvage revascularization procedures. Here, we tested the effect upon Arc expression of a novel antidepressant and selective 5-hydroxytryptamine/noradrenaline reuptake inhibitor (SNRI), (-)1-(1-dimethylaminomethyl) 5-methoxybenzocyclobutan-1-yl) cyclohexanol (S33005). Mice were sensitized and challenged with 2,4-dinitrochlorobenzene (DNCB). Activation of NADPH oxidase is accompanied by the phosphorylation of cytosolic components (p47-phox and p67-phox).

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The introduction of tumor necrosis factor-alpha antagonists in 1998 has had a significant impact on the treatment of rheumatoid arthritis. In particular, the new synthesis emphasizes the multicausal, fluid, contextual, and self-organizing nature of developmental change, the unity of perception, action, and cognition, and the role of exploration and selection in the emergence of new behavior. Photosonochemical degradation of butyl-paraben: optimization, toxicity and kinetic studies. The model plant Arabidopsis thaliana is widely studied for quantitative traits, especially via the utilization of natural genetic diversity. We evaluated whether pre-hospital G3 and its temporal behavior are associated with IS and salvage after pPCI. FD-CT is not yet equivalent to CT for imaging of brain parenchyma.

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In this study, we identified a gene (mvaT) encoding a negative regulator of cupA expression. In the framework of the HSS model, these materials have significant room for improvement and thus offer great promise as high-performance EUV resists for patterning of sub-10 nm features. Anomalies in protein synthesis: the release of soluble proteins from plant ribosomes. However, although many studies have investigated the hemolytic anemia following ABO-incompatible BMT, data regarding the occurrence of alloantibodies against red blood cell (RBC) antigens other than ABO in patients undergoing hematopoietic stem cell transplantation are limited. Moreover, the jaws may harbor nonodontogenic bone lesions not seen in any other part of the skeleton. Few randomised controlled trials (RCTs) recruit centres representatively, which may limit the external validity of trial results. Neuroendocrine tumors of the bronchopulmonary system (typical and atypical carcinoid tumors): current strategies in diagnosis and treatment. The patient shows an extremely poor long-term memory on both visually and verbally presented material, and of autobiographical events occurring after the onset of the illness, but some preserved memory functions on short-term memory tasks, semantic memory tasks, and implicit memory tasks.

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Recently, other T helper cells, that is, TH9 and TH17 cells, have been identified and these cells also contribute to asthma pathogenesis, the processes leading cordarone dose oral to formation or aggravation of asthma. Progressive primary complex, is the commonest thoracic form of tuberculosis while tuberculous meningitis is the commonest extra thoracic form. However, the importance of such information for the treatment of allergic disease is not known. It is concluded from these results that the relatively simple and fast cross-familiarisation taste aversion method is a suitable paradigm to study similarities in stimulus properties of different drugs. The influence of thyroglobulin on functional imaging in differentiated thyroid cancer. Local drug delivery agents as adjuncts to endodontic and periodontal therapy. S-antigen also induced superoxide production in rabbit peritoneal macrophages, but not in RAW 264.7. Cryo-electron tomography revealed that the drc3 mutant lacks a portion of the N-DRC linker domain, including the L1 protrusion, part of the distal lobe, and the connection between these two structures, thus localizing DRC3 to this part of the N-DRC. Characterization of tissue alkaline phosphatases and their partial purification by starch-gel electrophoresis.

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