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Atorvastatin

Atorvastatin is a lipid-lowering drug included in the statin class of medications. By inhibiting the endogenous production of cholesterol in the liver, statins lower abnormal cholesterol and lipid levels, and ultimately reduce the risk of cardiovascular disease. More specifically, statin medications competitively inhibit the enzyme hydroxymethylglutaryl-coenzyme A (HMG-CoA) Reductase, which catalyzes the conversion of HMG-CoA to mevalonic acid.

Other names for this medication:
Alipid, Ampliar, Anzitor, Atasin, Atenfar, Ateroclar, Atocor, Atorlip, Atorsan, Atorva, Atorvin, Atorvox, Atovarol, Atroact, Avascare, Avastatin, Biostatina, Cardyl, Dislipat, Finlipol, Fluxol, Holisten, Hypolip, Kolestor, Lipibec, Lipicon, Lipidra, Lipigan, Lipium, Lipizem, Lipodial, Lipostatin, Lipostop, Liptor, Livas, Lorvaten, Lowlipen, Prevencor, Sortis, Stacor, Tahor, Torid, Torivas, Trova, Vasolip, Voredanin, Xelitor, Zarator

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Description

{name} (atorvastatin) belongs to a group of drugs called HMG CoA reductase inhibitors, or "statins."

{name} is used together with diet to lower blood levels of "bad" cholesterol (low-density lipoprotein, or LDL), to increase levels of "good" cholesterol (high-density lipoprotein, or HDL), and to lower triglycerides (a type of fat in the blood).

{name} is used to treat high cholesterol, and to lower the risk of stroke, heart attack, or other heart complications in people with type 2 diabetes, coronary heart disease, or other risk factors such as genetically high cholesterol.

{name} is for use in adults and children who are at least 10 years old.

Dosage

Generic Atorvastatin can be taken in tablets. You should take it by mouth. It is better to take Generic Atorvastatin once a day at the same time with meals or without it. If you want to achieve most effective results do not stop taking Generic Atorvastatin suddenly.

Overdose

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Storage

Store at room temperature between 20 to 25 degrees C (68 to 77 degrees F) away from moisture and heat. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Atorvastatin are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Do not take Generic Atorvastatin if you are allergic to Generic Atorvastatin components. Be careful with Generic Atorvastatin if you're pregnant or you plan to have a baby, or you are a nursing mother. Generic Atorvastatin can ham your baby. Be careful with Generic Atorvastatin usage in case of having liver disease. Be careful with Generic Atorvastatin in case of taking erythromycin (E.E.S., E-Mycin, Erythrocin); cimetidine (Tagamet); ketoconazole (Nizoral) and itraconazole (Sporanox); spironolactone (Aldactone); oral contraceptives (birth control pills); cyclosporine (Neoral, Sandimmune); digoxin (Lanoxin); cholesterol-lowering medications as fenofibrate (Tricor), gemfibrozil (Lopid), and niacin (nicotinic acid, Niacor, Niaspan). Use Generic Atorvastatin with great care in case you want to undergo an operation (dental or any other). If you experience drowsiness and dizziness while taking Generic Atorvastatin you should avoid any activities such as driving or operating machinery. Avoid alcohol. Elderly people should be very careful with Generic Atorvastatin. Keep low-cholesterol and low-fat diet. Do not stop taking Generic Atorvastatin suddenly.

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Human faces can motivate nurturing behaviour or sexual behaviour when adults see a child or an adult face, respectively. These neuroimaging results provide evidence for the hypothesis that the neural representation of scenes is better understood within the broader theoretical framework of associative processing. Southwest Oncology Group 9504 demonstrated the feasibility and potential benefit of docetaxel consolidation after etoposide, cisplatin, and radiotherapy in patients with locally advanced non-small cell lung cancer. Uncertainty exists as to whether dysplastic polyps in ulcerative colitis should always be managed as dysplasia-associated lesions/masses requiring colectomy, or whether some can be managed by polypectomy. Anterolateral ankle impingement is due to entrapment of pathological tissues in the anterolateral aspect of the joint. Individual variation in morphological, physiological, and biochemical features associated with calling in spring peepers (Pseudacris crucifer).

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Importance of the functional state of the nervous centers in the rate of re-synthesis of glycogen in striated muscle. An imbalance of two functionally and phenotypically different subsets of plasmacytoid dendritic cells characterizes the dysfunctional immune regulation in multiple sclerosis. Semaphorin III has a highly dynamic expression pattern, which generally corroborates a chemorepellent guidance function, but also suggests additional functions, different from axon guidance. Histopathology of diarthrodial joints in ankylosing spondylitis. Many studies in acute pain management have been performed with rofecoxib. Their maturation to mature DC can be accelerated by inclusion of inflammatory stimuli in the co-culture. Various devices for central venous access are widely used in patients with cancer. Therefore, these two techniques can be used for nutritional assessment in hospitalized patients. Stochastic synchronization is a viable mechanism through which simple-spike synchrony could be generated, but it has received scarce attention, perhaps because the presence of feedforward inhibition in the input to Purkinje cells makes insights difficult. The aim of the study was to create a model for more effective gene transfer using adenovirus vectors carrying the lacZ-reporter gene (AdV-lacZ).

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A total of 15 different rice T-DNA flanking sequences were identified. Flutamide combined with sequential estrogen-progestogen preparations was given to patients in Group 1. To investigate the expression of inflammatory cytokine messenger RNA (mRNA) in peripheral blood mononuclear cells of patients with human T-cell lymphotropic virus type I (HTLV-I)-associated myelopathy (HAM). At saturating doses of 150 and 200 mg/kg, total amount of benzene metabolites excreted 24 h post-dose was predicted to be equivalent in 18-month mice and 3-month old mice, but the rate of elimination over time was shown to be decreased in 18-month vs. However, more randomized clinical trials are needed to confirm this conclusion. Differences between the vasorelaxant activity of adenosine-receptor agonists on guinea-pig isolated aorta precontracted with noradrenaline or phenylephrine. Data were analyzed and compared to results of a similar 2007 survey. Comparative study on functional conditions of sex glands in mice of high and low cancer strains. The ambient air quality in Central Europe appears to have the potential to adversely affect the productivity of the agroecosystems in that geographic area.

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Exposure to secondhand smoke and associated factors among non-smoking pregnant women with smoking husbands in Sichuan province, China. Sterile insects to enhance agricultural development: the case of sustainable tsetse eradication on Unguja Island, Zanzibar, using an area-wide integrated pest management approach. However, relatively little is known about the enzymes involved, their specificity for the different steroids, and their site of expression and action. Psychiatrists, clinical psychologists and school counsellors all need further education, targeting their group-specific proclivities, to improve their sensitivity and specificity in early identification of individuals at risk for schizophrenia. Rhynchelmis klamathensis differs from all Nearctic Rhynchelmis in lacking a filiform proboscis. To assess clinical efficacy of mineral water and perindopril in convalescents after hemorrhagic fever with renal syndrome (HFRS) in outpatient setting. Effects of unilateral cranial sympathectomy either alone or with sensory nerve sectioning on pedicle growth in red deer (Cervus elaphus). Studies on the standardization of the evaluation method of tuberculin test.

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This article reports a case of squamous cell carcinoma of the bladder which exhibited a migrated IUD into the bladder. Their application in psychotherapy research is demonstrated here for the first time. It was established that the activity of MAO-B in BM cervical intumescence is an objective DCP marker (within a time span of 12 hours). Iron entry in neurons and astrocytes: a link with synaptic activity. However, therapies based on MSCs are increasingly implemented to treat symptoms in which failure of the resident stem cells in situ, or malfunction of tissues or structures are not associated with immune cells or inflammation, but instead are associated with mechanical or metabolic stress, ageing, developmental or acquired malformations, and other causes.

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Resource allocation to flowers, fruits and seeds can vary greatly within an inflorescence. Estimation of myocardial perfusion changes with single-photon emission computed tomography during early postoperative period, particularly after 6 months, confirms excellent and final results of complete surgical myocardial revascularization. Activation of sigma E depends on sigma F, the factor that governs transcription in the forespore. Two models were created, one including antepartum and one including antepartum and intrapartum variables. A pilot study of iPad-assisted cognitive training for schizophrenia. The strong radical scavenging activity of chloroform and ethyl acetate extracts could be explained by the presence of nepodin as well as by the high phenolic content of the ethyl acetate extract. An outbreak of enteric adenovirus type 41 endemic in Fjieda, Japan. Moreover, LA provoked a down regulation of two anti-apoptotic proteins, Mcl-1 and Bcl-xL protein and a strong induction of the BH3-only protein Bim.

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Effects of smoking on thermal pain threshold in deprived and minimally-deprived habitual smokers. Autoantibodies directed against the ribosomal proteins P0, P1 and P2 (P proteins) are specific for systemic lupus erythematosus (SLE) and there are some evidences that they could be related to the neuropsychiatric manifestations of the disease. The scTARC was correlated with the severity of local skin lesions, especially with the erythema, edema/papule, and oozing/crusts score. The pulmonary and systemic circulations in congenital heart disease. Mycobacterium africanum is not a major cause of human tuberculosis in Cape Town, South Africa. If larger prospective studies confirm these findings, D-dimer assessment may hence become an integral part of the clinical decision-making in patients with AF.

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The present study examined whether the disruption by MK-801 is reversible in rats pretreated with the classical antipsychotic haloperiodol or the atypical antipsychotic clozapine. Decoration of carbon nanotubes with metal nanoparticles by wet chemical method: a small-angle neutron scattering study. Effect of N-acetylcysteine on mitochondrial function following traumatic brain injury in rats. Evidence for two loci on chromosome 1 linked to the mild form was found. The differences indicated by the pooled analysis for coccidia were most likely due to an uneven host age distribution with respect to survival, combined with an uneven distribution of the oocyst counts with rabbit age.

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However, the function of SALL2/Msal-2 still needs to be determined. Changes in the arterial amounts of small leucine-rich proteoglycans, known to be involved in collagen fibrillogenesis, and of some nonfibrillar collagens in combination with alterations in proteins related to functions of the human arterial smooth muscle are associated with arterial stiffness, as determined by PWV. This clinical trial demonstrated that butoconazole 1-BSR is an effective and safe alternative to longer-term therapy with miconazole nitrate (seven days) for vulvovaginal candidiasis. Marked geographic aggregation of acute intermittent porphyria families carrying mutation Q180X in Venezuelan populations, with description of further mutations. Depersonalisation disorder has also been associated with autonomic blunting and hypothalamic-pituitary-adrenal axis dysregulation. Effect of buthionine sulfoximine on the sensitivity to doxorubicin of parent and MDR tumor cell lines.

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A phase III randomized trial of the timing of meloxicam with iodine-125 prostate brachytherapy. Antibiotic activity of microcide and penicillin in their combined application. Evolution of these tumors, with a maxillo-facial preferential location, is usually longer than for other cutaneous carcinomas. Tumor heterogeneity is one of the most important and challenging problems not only in studying the mechanisms of cancer development but also in developing therapeutics to eradicate cancer cells. Therefore, we generated XP-A patient-derived human induced pluripotent stem cells (XPA-iPSCs) to produce in vitro models of neurological disorders. Numerous studies have shown that there is little direct relationship between pain and disability and suggest that the biopsychosocial approach offers the foundations for a better insight in how pain can become a persistent problem. The importance of social pediatry knowledge in pediatric primary care. Tetracene is well known for its high singlet fission (SF) efficiency, which could be used to enhance the energy conversion efficiency in solar cells.

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Abnormal expression of cyclooxygenase-2 (COX-2) and prostaglandin (PG)E(2) is an important mediator in inflammation and tumor promotion. We find that the isomerization process controls the heterogeneity and the non-gaussian parameter of the material, leading to extremely rapid variations of these quantities. Modafinil enhanced visual short-term memory storage capacity in low-performing participants. A boundary integral formulation for the solution of the Helmholtz equation is developed in which all traditional singular behaviour in the boundary integrals is removed analytically. This study found a high rate of Pneumocystis colonization among HIV-infected patients.

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Performance and kinetic evaluation of the anaerobic digestion of two-phase olive zantac 20 mg mill effluents in reactors with suspended and immobilized biomass. The central cavity is effectively sealed at the top and bottom of the complex but has small inter-arm holes when viewed from the side. The evolution of the daily rhythm of the circulating eosinophils during inanition and resumption of feeding. DNA fingerprinting employing a minisatellite Myo probe was used for individual identification and paternity determination in Hokkaido brown bears (Ursus arctos yesoensis). The dangers and prospects of lengthy rehabilitation processes are discussed.

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Based on mutation rates, we have classified triplets (not just codons) into stable, unstable and intermediate groups. Assessment of severity of mechanical prosthetic mitral regurgitation by transoesophageal echocardiography. Linear regression analyses were performed on the logarithmic CV of SNR-AUC against the average MD, PSD, and SNR-AUC. A recombinant pseudorabies virus that is defective in the early protein 0 (EP0) and large latency transcript (LLT) genes was constructed. We discuss a splitting of the Dirac points that leads to phonon bands with nonzero Chern numbers, signaling the existence of topological vibrational modes localized at MTs edges, which we indeed observe after explicit calculations. The localized approach revealed patterns of age-related change that were not apparent in the ring averages. Castration and adrenalectomy as related to the management of prostatic and breast cancer.

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The biosynthesis of uroporphyrinogen III, the precursor of hemes, chlorophylls, corrins and related structures, is catalyzed by the porphobilinogenase system (PBGase), a complex of two enzymes, PBG-Deaminase (PBG-D) and Isomerase. Antimycobacterial therapy is effective, and probably more efficient when combined with corticosteroids, but the regimen and duration of the treatment are not standardized. Simultaneously, the triglyceride and lipoprotein (a) levels were higher in the estrogen group. A comparative study to evaluate the effect of honey dressing and silver sulfadiazene dressing on wound healing in burn patients. Targeted injury prevention strategies in this group seem justified. Our results increase our understanding of several aspects of the molecular crosstalk between host and parasite, which might be useful in designing anthelmintic drugs that exclusively impair parasitic proteins which mediate cell signaling and pathogenic reproduction and establishment. The impact of schistosomiasis on infertility may be underestimated according to recent literature. Chylous ascites in a cheetah (Acinonyx jubatus) with venoocclusive liver disease. To determine whether kisspeptin-54 modulates GH, prolactin and TSH secretion in healthy women. Routine upper gastrointestinal tract evaluation before renal transplantation - is it a must in all patients?.

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Reinfection with Legionella pneumophila documented by pulsed-field gel electrophoresis. This was repaired laparoscopically with a prosthetic mesh using a transperitoneal approach. Small intestinal bacterial overgrowth prevalence in celiac disease patients is similar in healthy subjects and lower in irritable bowel syndrome patients. The grading of long-tubular-bone pseudarthrosis depends on the biological reaction or lack of reaction in pseudarthrosis or non-unions. Clinician-patient communication is central in palliative care, but it has not been described qualitatively which specific elements of communication are important for high-quality palliative care, particularly in the inpatient setting. The reflective properties of different types of dinoflagellate eyespots were investigated using confocal laser scanning microscopy in the epireflection contrast mode. Observations on essentially normal young men treated with ACTH and cortisone. By contrast, HU-treated wild-type and atr plants arrested in G1 and showed no obvious signs of cell death. An observational study of comorbidity and healthcare utilisation among HIV-positive patients aged 50 years and over. Exclusion criterion was the administration of cytostatic agents prior to diagnosis.

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The integrin alpha prilosec otc dosage 20 mg (9)beta(1) binds to a novel recognition sequence (SVVYGLR) in the thrombin-cleaved amino-terminal fragment of osteopontin. After a year of implementation, we confirmed that a single framework with set criteria is able to benchmark services across healthcare systems worldwide. The physical effects caused by the introduction of metal or other conductive materials into a magnetic field and their consequences are presented. To update the 2004 USPSTF review on screening for HBV infection in adolescents and adults. Cholesterol inhibits glutamine metabolism in LLC WRC256 tumour cells but does not affect it in lymphocytes: possible implications for tumour cell proliferation. Population-based databases concerning aspects of public health genetics are largely unavailable at the state level.

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Crystals are frequently observed in cells infected with ECHO viruses 6 and 19, consisting of dense particles with an average diameter of 14.4 mmicro ranging from approximately 13.2 to 15.6 mmicro for ECHO virus 6, and 14.5 mmicro ranging from approximately 12.5 to 16.5 mmicro for ECHO virus 19. For a liquid film resting on an elastomeric layer, substrate deformability has a destabilizing effect, as evidenced by an increase in the maximum growth rate and range of unstable wavenumbers. The study comprised two groups: nontumoral bladder tissue specimens from 20 patients loxitane generic name (group I) and tissue specimens from 61 patients with bladder carcinoma (group II). Connective tissue metabolism including cytokines in scleroderma. To further test the hypothesis that IL15 directly modulates GABA turnover by reuptake mechanisms, the dose-response relationship of IL15 on (3)H-GABA uptake was determined in two neuronal cell lines. This study was performed to evaluate a prototype balloon-tipped, flow-directed catheter for use during intracardiac echocardiography in seven dogs. Some preliminary in vitro and in vivo results from the system are presented. Workstyle in office workers: ergonomic and psychological reactivity to work demands. After cryostorage, germination in vitro (1/6- or 1/3-strength MS medium) increased compared to germination on peat moss. Regardless of bai specific species composition, significantly higher concentrations of Na, K, and Ca were found in consumed plants, and other trace minerals were more common in consumed plants.

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In humans, sham-feeding increases bicarbonate secretion in both the stomach and duodenum which is mediated by cholinergic vagal fibres in the stomach, but seems to be noncholinergic in the duodenum. Therefore, we conducted this meta-analysis to evaluate the efficacy of the combination therapy of PTH with alendronate in the treatment of patients with osteoporosis. The motor nucleus region of the lumbar thickening was studied both in normal animals and after the experimental destruction of cerebral nuclei. Although some studies have evaluated transfer techniques with similar methodology, this study demonstrated the most suitable strain gauge setup to record framework deformations in all directions and simultaneously offset the effects of temperature variation. in the studied myeloma and low grade lymphoma patients anemia did not depend on defective Epo secretion.

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