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Axedol (Tramadol)

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Axedol is a strong painkiller used to treat moderate to severe pain. It is generally used when non-opioid painkillers don't work as well to control the pain anymore. Axedol may cause drowsiness. You shouldn't drive or use heavy machinery or perform dangerous activities until you know how this drug affects you.

Other names for this medication:
Accupain, Adamon, Antram, Bolodol, Cemadol, Contramal, Dolstar, Ivydol, Lagesic, Madol, Mandol, Painadol, Postadol, Radol, Ramax, Redimol, Relidol, Ryzolt, Sigmadol, Simol, Tacil, Tradol, Tramadex, Trasic, Trofel, Ultrazac, Vegadol, Xidol, Zamadol

Similar Products:
Aldara, Singulair, Buspar, Sporanox, Xenical, Calan, Desyrel

Also known as: Tramadol


{name} ER is an pain medicine similar to an opioid. This medicine is used to treat moderate to severe pain.

The extended-release form of tramadol is for around-the-clock treatment of pain. This form of tramadol is not for use on an as-needed basis for pain.


Follow the directions on your prescription label and read all medication guides. Never use Axedol ER in larger amounts, or for longer than prescribed. Tell your doctor if you feel an increased urge to take more of Axedol ER.

Never share Axedol ER with another person, especially someone with a history of drug addiction. MISUSE CAN CAUSE ADDICTION, OVERDOSE, OR DEATH. Keep the medicine where others cannot get to it. Selling or giving away this medicine is against the law.

Stop taking all other opioid medications when you start taking Axedol ER.

Axedol ER can be taken with or without food, but take it the same way each time.

Swallow the capsule or tablet whole to avoid exposure to a potentially fatal overdose. Do not crush, chew, break, open, or dissolve.

Measure liquid medicine with the supplied syringe or a dose-measuring device (not a kitchen spoon).

Never crush or break a Axedol ER pill to inhale the powder or mix it into a liquid to inject the drug into your vein. This practice has resulted in death.

You may have withdrawal symptoms if you stop using Axedol ER suddenly. Ask your doctor before stopping the medicine.

Store at room temperature away from moisture and heat. Keep track of your medicine. You should be aware if anyone is using it improperly or without a prescription.

Do not keep leftover Axedol ER. Just one dose can cause death in someone using it accidentally or improperly. Ask your pharmacist where to locate a drug take-back disposal program. If there is no take-back program, mix the leftover medicine with cat litter or coffee grounds in a sealed plastic bag throw the bag in the trash.

Detailed Axedol ER dosage information


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose can be fatal, especially in a child or other person using the medicine without a prescription. Overdose symptoms may include severe drowsiness, pinpoint pupils, slow breathing, or no breathing.

Your doctor may recommend you get naloxone (a medicine to reverse an opioid overdose) and keep it with you at all times. A person caring for you can give the naloxone if you stop breathing or don't wake up. Your caregiver must still get emergency medical help and may need to perform CPR (cardiopulmonary resuscitation) on you while waiting for help to arrive.

Anyone can buy naloxone from a pharmacy or local health department. Make sure any person caring for you knows where you keep naloxone and how to use it.


Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) away from moisture, light and heat. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Axedol are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


You should not take Axedol if you are allergic to tramadol, or if you have:

severe asthma or breathing problems; a stomach or bowel obstruction (including paralytic ileus); if you have recently used alcohol, sedatives, tranquilizers, or narcotic medications; or if you have used an MAO inhibitor in the past 14 days (such as isocarboxazid, linezolid, methylene blue injection, phenelzine, or tranylcypromine).

Axedol should not be given to a child younger than 12 years old. Axedol ER should not be given to anyone younger than 18 years old.

Do not give Axedol to anyone younger than 18 years old who recently had surgery to remove the tonsils or adenoids.

Seizures have occurred in some people taking Axedol. Your seizure risk may be higher if you have ever had:

a head injury, epilepsy or other seizure disorder; drug or alcohol addiction; or a metabolic disorder.

To make sure Axedol is safe for you, tell your doctor if you have ever had:

breathing problems, sleep apnea; liver or kidney disease; urination problems; problems with your gallbladder, pancreas, or thyroid; a stomach disorder; or mental illness, or suicide attempt.

If you use tramadol during pregnancy, your baby could be born with life-threatening withdrawal symptoms, and may need medical treatment for several weeks.

Ask a doctor before using tramadol if you are breastfeeding. Tell your doctor if you notice severe drowsiness or slow breathing in the nursing baby.

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IL-1 and TNF-alpha play a pivotal role in the host immune response in a mouse model of Staphylococcus aureus-induced experimental brain abscess. An anti-VEGF ribozyme embedded within the adenoviral VAI sequence inhibits glioblastoma cell angiogenic potential in vitro. Vascular permeability is essential for the health of normal tissues and is an important characteristic of many disease states. Behavioral disorders of adolescents are numerous and heterogeneous. However, numerous alterations to the EGCG molecule have been patented, either to improve the integrity of the native compound or to generate a more stable yet similarly efficacious molecule. In this Letter we report on an alternative approach to get multiple images in microscopy, exploiting the capabilities of both a lithium niobate diffraction grating and digital holographic technique.

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A retrospective review of patients with abnormal cervical cytology who underwent S and T at MSMC between January 2008 and December 2012 was conducted. The medical records of 45 patients who had been diagnosed with AI between January 1991 and December 2002 in the adult allergy unit and who underwent surgery in the same hospital in the last 4 years were retrospectively analyzed. The degraded nature of cell-free fetal RNA presented technical challenges for the RNA-Seq approach. Subsequently, we confirmed that these inhibitors protect against BoNT/A in a dose-dependent manner in human ES-MNs. We also experimentally quantified larval movement by tracking larvae swimming in low-intensity shear while simultaneously mapping the surrounding flow fields. These results show that the cardiac pump has a more restricted what is the max dosage of effexor response in CRF patients. Leukocyte CD11b and CD62l expression in response to interstitial inflammation in CAPD patients. However, the result of the quantiferon alpha-2b test was negative.

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There are scarce data regarding the circadian pattern of symptoms onset in young patients presenting with acute myocardial infarction (AMI). Stress related to surgery and critical illness depletes thiamine, essential in energy metabolism, and might result in high blood lactate concentrations and higher mortality. This is now changing as a growing body of research shows that the primary and secondary meristems share some common fundamental regulatory mechanisms. These results provide insight into the effects of these 3 adjuvants and may facilitate appropriate use off adjuvants by researchers using DNA vaccines in laboratory animals. Characteristics of patients with Banff borderline changes in renal allograft biopsies. The proposed MR cerebellar algorithm was useful to guide genetic/malformative or biochemical investigations, allowing an etiological diagnosis in 55 children. 12-hour burst-suppression anesthesia does not relieve medication-resistant cymbalta dosing epocrates major depression. Then, we characterize our optimal controls in terms of the solutions to the optimality system, which is the state system coupled with the adjoint system. Addition of excess PG to the bacterial culture reversed the inhibitory effect of sMD-2 on the growth of B. An uncontrolled pilot study with integral process evaluation conducted at three general practices in northwest London, UK (November 2012-April 2013).

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If these tests are to be used as outcome measures, account must be taken of the size of the typical fluctuation in measurements shown. These findings highlight a dysregulated innate immune response with over-expression of molecules associated with leukocyte recruitment and activation that may eventuate in the hallmark chronic immune-mediated inflammation of UC. This filamentous array can be greatly depleted by digestion with proteinase K and trypsin, but pepsin has less effect. Rhythmical contractions (4 min-1) were more common during the second and third postnatal weeks and were always preceded by large, slow depolarizations (5-40 mV). Ynamides consist of a polarized triple bond that is directly attached to a nitrogen atom carrying a sulfonyl, an alkoxycarbonyl, an acyl or another electron withdrawing group. Comparable results were found for Hamilton anxiety and clinical global impressions scales and were most pronounced for the Zung self rating depression scale. Management of obstructive sleep apnea syndrome in children with craniofacial malformation. The sex of the plant affected the pattern of SLM2 and SLM3 expression in the petal and stamen whorls, resulting in a smaller fourth whorl in male flowers than in female flowers.

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plzfa was observed in the brain, neural rod and sensor organs including the eyes, ears and nose during embryogenesis. In this paper, we model the early development of the human placenta, based on the hypothesis that this is driven by a chemoattractant effect emanating from proximal spiral arteries in the decidua. More studies are needed to further validate the results of our study. A Cox regression analysis was used for a multivariable risk model, and a simplified integer model was derived. Fluoride exposure was the sole predictor of primary tooth fluorosis in a multivariate model. Surrounding the cell body and dendrites of the non-phasic firing neurons, many astrocytes were seen to form contact with the neurons, whereas the phasic firing neurons formed contact with the astrocytes through the dendrites. Diagnosing bipolar disorder: Defining thresholds and setting boundaries. The technique can also be applied to monitoring fermentation and downstream purification steps.

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The model was used to simulate the period from death until metabolic activity ceased, in order to predict the different stages of metabolic response to anoxia. Transcription of human resistin gene involves an interaction of Sp1 with peroxisome proliferator-activating receptor gamma (PPARgamma). One hundred thirty-five (72 African American and 63 white) men and women underwent 24-hour blood pressure monitoring and arm ischemia pain sensitivity evaluation with both standard verbal rating scales and individually ordered verbal rating scales of intensity and unpleasantness. Interdisciplinary physical activity counseling in primary care: a qualitative inquiry of the patient experience. A hybrid approach of synthetic biology coupled with fine-tuning through evolution is suggested. The administration of the lowest aspirin doses induced a pro-thrombotic effect stronger than the antithrombotic effect of COX 1 selective inhibition.

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As colorectal malignancies are relatively well treatable and show acceptable survival rates, the quality of life indicators are very important in this group of patients. Herpes simplex Virus (HSV) 1 and arboviruses (flaviruses) are the most common causes of encephalitis in Switzerland. We found that neonate snakes born to females from populations characterized by different predator and prey environments did not differ in energetic intake, but snakes from the population containing large prey grew significantly faster than those from a population containing small prey. The decreased amount of Bcr-Abl/c-Abl was accompanied by: alterations in telomeric associated proteins-overexpression of tankyrase and decreased amount of TRF1/Tin2 protonix medication sheet , cell growth arrest of K-562 cells, reaching a plateau after 6 days treatment, and increased proliferating activity of Jurkat cells. Additionally, an exaggeration of this peripheral metabolism has been associated with acne in women.

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Mutations of the cystic fibrosis transmembrane conductance regulator (CFTR) gene are associated with chronic pancreatitis in Caucasians. Moreover, the technique appears superior to others for describing microvascular architecture and determining the presence or absence of flow. Differences in anxiety and depression between male and female caregivers of children with a disorder of sex development. Urapidil enhanced extracellular glucose level at high concentration. The reported case is a 66-year-old man with a history of thyroid cancer treated with surgery and radiotherapy at the age of 36 years. Global neural pattern similarity as a common basis for categorization and recognition memory. Surgical treatment of ascites in liver cirrhosis by ligating half of the branches of the upper and lower mesenteric artery. These outcome studies utilized a wide array of theoretical orientations and intervention delivery, as well as an assortment of outcomes measurement.

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This article reviews our current understanding of mechanisms that mediate the activation of caspases. The presence of histamine in the culture supernatant of Vibrio anguillarum, which produces Hdc and secretes the histamine-containing siderophore anguibactin, was detected by thin-layer chromatography. The authors conducted a retrospective analysis of 683 physicians referred for assessment at the Center for Personalized Education for Physicians from 2000 to 2010, who were evaluated as either safe or unsafe to return to practice. The battery was then carefully removed using magnetic and balloon catheters under fluoroscopic guidance. To examine the influence of cisapride on the pharmacokinetics of ethanol and the impact of gastric emptying monitored by the paracetamol absorption test. We believe that these results reopen the question of the role of phonological awareness in reading in Chinese and, more generally, the nature of the mechanisms underlying this relationship. Rheological properties of high-viscosity solutions of lung molecules. Incorporation of short chain fatty acids into phospholipides by the rat.

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