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Axtrip (Amitriptyline)

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Axtrip is an antidepressant medication that is sometimes prescribed off-label to manage chronic back pain. It is one of the drugs in a class of drugs known as tricyclic antidepressants. Axtrip is not a narcotic (opioid) drug, and there is not usually an addiction risk with the medication.

Other names for this medication:
Abamax, Amiclozor, Amicon, Amicure, Amiline, Amimax, Amitin, Amitone, Amitriptyline, Amitrix, Amitryn, Amizep, Amoten, Amsha, Anitryp, Axtrip, Emotrip, Estiline, Gentrip, Latilin, Latiln, Lodep, Mitrip, Normaline, Psycomer, Raitrip, Sarotena, Sereval, Triplent

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Also known as: Amitriptyline


Axtrip target is the treatment of depression. Axtrip is acting by increasing the amounts of certain natural substances in the brain that are needed to maintain mental balance. It is tricyclic antidepressant. Generic name of Axtrip is Amitriptyline. Axtrip is also known as Amitriptyline, Amitryptyline, Amidon, Amitryn, Tryptanol, Endep, Elatrol, Tryptizol, Trepiline, Laroxyl, Saroten, Triptyl, Amitrip. Brand names of Axtrip are Axtrip, Endep, Vanatrip.


Usual Adult Dose for Depression:

OUTPATIENTS: -Initial dose: 75 mg orally per day in divided doses; this may be increased to 150 mg/day (if needed) -Maintenance dose: 40 to 100 mg orally per day -Maximum dose: 150 mg/day Alternate outpatient treatment regimen: 50 to 100 mg orally as a single dose at bedtime; this may be increased by 25 or 50 mg as needed at bedtime to a total of 150 mg/day INPATIENTS: -Initial dose: 100 mg orally per day -Maintenance dose: 40 to 100 mg orally as a single dose at bedtime -Maximum dose: 300 mg/day Comments: -Dose increases should preferably be made in the late afternoon or at bedtime due to the sedative effect. -The full therapeutic effect may take as long as 30 days to develop. -Maintenance doses should be reduced to the lowest amount that will maintain relief of symptoms when satisfactory improvement has been obtained. -Maintenance therapy should be continued for 3 months or longer to lessen the possibility of relapse. Use: Relief of symptoms of depression

Usual Geriatric Dose for Depression:

10 mg orally 3 times a day AND 20 mg orally once a day at bedtime Comments: -The full therapeutic effect may take as long as 30 days to develop. -Elderly patients should be monitored carefully and serum levels obtained as clinically appropriate. -Dose adjustments should be made according to clinical response. Use: Relief of symptoms of depression

Usual Pediatric Dose for Depression:

12 years or older: 10 mg orally 3 times a day AND 20 mg orally once a day at bedtime Comments: -The full therapeutic effect may take as long as 30 days to develop. -Dose adjustments should be made according to clinical response. Use: Relief of symptoms of depression

Detailed Axtrip dosage information


If you overdose Axtrip and you don't feel good you should visit your doctor or health care provider immediately. Symptoms of Axtrip overdosage: seizures, loss of consciousness for a period of time, seeing things or hearing voices that do not exist, agitation, feeling drowsy, rigid muscles, vomiting, high temperature, cold body temperature, problems concentrating, abnormal heartbeats, confusion.


Store at room temperature between 20 and 25 degrees C (68 and 77 degrees F) away from moisture and heat. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Axtrip are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


You should not use Axtrip if you are allergic to amitriptyline, or:

if you have recently had a heart attack.

Do not use Axtrip if you have used an MAO inhibitor in the past 14 days. A dangerous drug interaction could occur. MAO inhibitors include isocarboxazid, linezolid, methylene blue injection, phenelzine, rasagiline, selegiline, tranylcypromine, and others.

Tell your doctor if you have used an "SSRI" antidepressant in the past 5 weeks, such as citalopram, escitalopram, fluoxetine (Prozac), fluvoxamine, paroxetine, sertraline (Zoloft), trazodone, or vilazodone.

To make sure Axtrip is safe for you, tell your doctor if you have ever had:

bipolar disorder (manic-depression) or schizophrenia; mental illness or psychosis; liver disease; heart disease; a heart attack, stroke, or seizures; diabetes (amitriptyline may raise or lower blood sugar); glaucoma; or problems with urination.

Some young people have thoughts about suicide when first taking an antidepressant. Your doctor should check your progress at regular visits. Your family or other caregivers should also be alert to changes in your mood or symptoms.

Tell your doctor if you are pregnant or breastfeeding.

Axtrip is not approved for use by anyone younger than 12 years old.

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Selecting nitrifying inocula on different ammonium concentrations. Flavonoids, induced proteins, and peroxidase activity were revealed in root tissues of SA-treated plants after challenge by Foa. These findings suggest exposure to amphetamine activates the same medial prefrontal cortex regions responsible for integration of responses to stress, and suggest the potential for AP1-glucocorticoid cross-talk in these cell populations. Dehydration is the most common fluid and electrolyte problem among elderly patients. A large proportion of patients presenting to our unit are in a reasonably stable condition after resuscitation, and rapid diagnosis may be difficult. T-scores determined by DXA measurements at the spine and hip and QUS measurements at the calcaneus provide similar information regarding the discrimination of women with and without vertebral fractures. With electron microscopy, preliminary results showed immunoreactive fibers in close apposition to unlabeled cell bodies or dendrites. Early recurrence in standard-risk medulloblastoma patients with the common idic(17)(p11.2) rearrangement. Abnormal anatomy complicates the management of atrioventricular nodal reentrant tachycardia. A four-armed olfactometer, a design widely used to observe orientation responses in various insects and parasitoids in particular, was chosen to investigate the dose-response relationship.

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Acute rheumatic fever: Findings of a hospital-based study and an overview of reported outbreaks. Cone photoreceptor betagamma-transducin: posttranslational modification and interaction with phosducin. This report describes the occurrence of human eggs fertilized by two spermatozoa and the variable developmental potentials expressed by the resultant embryos. The second projectile pushed out this explosion gas to the skin that had been uncovered in a star-shaped way by the first shot. To one half of the split units, four grams of phosphate charged Amberlite IR-45 resin were added, while no additions were made to the other split units. It has been used off-label to treat and manage autoimmune and dermatologic diseases as an alternative or adjuvant therapy to systemic treatments. Both hypobromite and cyclohexanedione modified guanidino groups of arginyl residues. Olfactory sensilla on antennae and maxillary palps of Fannia hirticeps (Stein, 1892) (Diptera: Fanniidae). Immunobiologic study of the role of heterogenetic antigens of uropathogenic strains of E. Compared to FVIII-/- mice, FVIII-/-/Nu and Nu mice showed greater degree of wound contraction and loss of the crust.

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Ineffective airway management will lead rapidly to hypoxaemia, and will ultimately compromise patient care. Demonstration of Shot-noise-limited Swept Source OCT Without Balanced Detection. A 2.2 kilobase (kb) fragment of ColIdrd-1 cloned in pBR325 causes phage T5 and BF23 infections of Escherichia coli K-12 to abort. The risk factors acting synergistically with OC, have all been shown to increase platelet reactivity. We observed a clear schedule-dependent radiosensitization by gemcitabine. SARPE can be effectively performed with a more conservative vestibular incision to prevent excessive scarring and shortening of the lip to achieve predictable results. Relevance of three-dimensional reconstructions of stain distributions for structural analysis of biomolecules.

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Disparate in vivo efficacy of FTY720 in xenograft models of Philadelphia positive and negative B-lineage acute lymphoblastic leukemia. We review the epidemiology of renal recovery and of the association between AKI and the development of CKD. High lifetime prevalence of back pain was observed in undergraduate students. The interferon-induced transmembrane (IFITM) proteins can restrict entry of ebolaviruses, influenza A viruses, and other enveloped viruses. Channel-wise group analysis confirmed the robustness of the fNIRS technique to head nodding movements but showed a large effect of raising eyebrows in both signal quality control metrics, both during task and rest conditions. For one inhibitory connection it was demonstrated that subthreshold depolarization of the presynaptic neuron was sufficient to cause release of transmitter at the synapse. Three to four days before delivery and prior to other organs renin was found in the fetal kidney.

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Using the technique of laser photolysis and spectroscopy, we have observed excited singlet state absorption bands in 1,2-benzanthracene at 560 and 520 nanometers. Of the LHRH analogs used, two revealed immunoreactive material in median eminence and not pineal, two stained pineal only, and three stained median eminence and pineal. Elective extirpation of varicose veins allows the healthy venous trunks to be conserved (reconstructive surgery) and scars are practically invisible. Currently, various groups are investigating means to improve gene delivery and clinical responses by continuing to modify gene delivery vectors and by concentrating on combination gene therapy and multimodality therapy. Family studies have suggested that eating disorders and mood disorders may coaggregate in families. In tests of local and systemic reactogenicity, it was found that at both dosages the subunit vaccine caused a low frequency of minor adverse reactions. Student pharmacists in their second professional year in the Doctor of Pharmacy degree program at our institution were randomly selected from volunteers to participate.

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The composition and polish of CAD/CAM materials affects gloss and stain resistance. Providing epidemiological data and treatment of anemia in lung cancer patients undergoing first-line chemotherapy. The effect of bacterium bifidum on intestinal bacterial flora and toxic protein metabolites in chronic liver disease. Primary outcome measures included two pre-test and two post-test video-recorded role-play interviews scored by blinded raters with expertise in human resources and self-reported interviewing self-confidence. Changes in pathway activation that occur between early stage prostatic epithelial lesions, prostatic stroma and the extracellular matrix can be analyzed by obtaining pure populations of cell types by laser capture microdissection (LCM) and analyzing the relative states of several key phosphorylation points within the cellular circuitry. These findings suggest that it will be critical to keep health literacy in mind in implementing the law--for example, in the design of eligibility documents and required forms, insurance exchange interfaces, and educational and outreach campaigns related to the Medicaid expansion and the insurance exchanges. Major regulatory, financial, and clinical changes were required within and among the various partners in the Washtenaw County Integrated Health Care Project. Described is a new enzyme assay for neuraminidase that can be applied to the bioassay of interferons.

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Effect of ragweed hyperimmune human gamma globulin on in vivo and in vitro parameters of ragweed sensitivity. Absence of association between SPINK1 trypsin inhibitor mutations and Type 1 or 2 diabetes mellitus in India and Germany. Potential mechanisms behind the antioxidant actions of prolactin in the retina. Interestingly, both radiofrequency and chemical ablation decreased the myocardial and glomerular fibrosis of SHR, while neither increased the plasma creatinine and blood urea nitrogen nor affected the urinary excretion of electrolytes and protein when compared to sham group. In particular, we performed two rTMS experiments, which differed only for the target sites stimulated, on independent samples of participants. Association between rat serum alpha-macroglobulins and splenic macrophages. MYOCARDIAL INFARCT WITH TOTAL ATRIOVENTRICULAR BLOCK AND MORGAN-ADAMS-STOKES ATTACKS. Research into the pathophysiology of bipolar disorder (BD) is limited by the inability to examine brain cellular processes in subjects with the illness. Reasoning about bedrock abstract concepts such as time, number, and valence relies on spatial metaphor and often on multiple spatial metaphors for a single concept.

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An open label study of oral transmucosal fentanyl citrate (OTFC) for the treatment of breakthrough cancer pain. Selection criteria were R0 resection, pathological M0 stage and pathological lymph node involvement. Raw data were not available for several primary studies that have been published previously. Expression of E-cadherin and vimentin in oral squamous periactin medication side effects cell carcinoma. This immunosuppressed state was transferable into ALS-treated syngeneic F344 rats by nylon-wool-nonadherent spleen cells. These patients infected with HCMV experience an imbalance of redox homeostasis that cause accumulation of reactive oxygen species (ROS) at the cellular level. The reconstruction of a fragment of primordial genetic information from modern proteins: PGI-FI (AHAP). A closer look at the basic immunopathologic process during the growth of melanomas is might lead to a more effective control of this malignancy.

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We compared the acute effect of intraperitoneal amino acid administration with that of intraperitoneal glucose administration on vascular function in peritoneal dialysis patients. Besides their significant role as membrane components, C20 PUFAs serve as precursors for eicosanoids, hormone-like mediators of reproduction, immunity and ion transport physiology. coli J5, the ability of these additional C1 molecules to alter later events in the C cascade may depend on the control of C1 activation and its subsequent activity when bound to different membrane components. Correlation was not observed between CSF lactate and rCBF or between CSF pH and rCBF. Recent studies found that distinct MBL2 and FCN2 promoter variants and their corresponding serum levels are associated with relative protection from urogenital schistosomiasis. from Qinghai, Madang, Ningxian and Lintan, which was identical to the unidentified Theileria sp. However, the in vivo mechanism of TR action remains poorly explored. Spectral, morphological, linear and nonlinear optical properties of nanostructured benzimidazole metal complex thin films. SWAN imaging when added to the conventional MRI protocol for population screening for NCC in endemic regions improves both lesion detection and definitive diagnosis of neurocysticercosis.

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Left ventricular outflow tract obstruction after mitral valve repair assessed with intraoperative echocardiography: noninterventional treatment. No release of luteinizing hormone in response to thymosin was observed from pituitaries superfused alone. These unexpected non-zero probabilities are still present when non-separable Coulomb interaction or non-symmetrical potentials are considered. The pronounced hypotension and tachycardia was absent after spinal transection, hexamethonium pretreatment or adrenal demedullation. Electrophysiological Adverse Effects of Direct-Acting Antivirals in Patients With Chronic Hepatitis C. The results provide the geometric parameters necessary for the three-dimensional reconstruction of the articular surfaces of the femoral condyles. Peanut-free schools: What does it really mean, and are they necessary?. Notch signaling thus provides a constitutive drive on expression of the major nitric oxide receptor (GUCY1A3/GUCY1B3) in arteries from mice, rats, and humans, and this control mechanism is disturbed in hypertension can depakote overdose cause death . The impact of somatic health problems on insomnia in middle age. Phase I/II trials commenced in March 2001 and were ongoing as of June 2003.

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