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Azelastine is a moderately priced drug used to relieve itching, running, and stuffiness in the nose. It is slightly more popular than comparable drugs. It is available in multiple generic and brand versions. Azelastine is covered by most Medicare and insurance plans, but some pharmacy coupons or cash prices may be lower.

Other names for this medication:
Astepro, Azelast, Azelastine, Azenate, Duonase, Nazomac, Oculast, Optihist, Optivar

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Minipress, Celebrex, Biaxin, Xanax, Seroquel, Reminyl, Avelox, Duricef, Buspar, Glyburide

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{name} (azelastine) is an antihistamine that reduces the effects of natural chemical histamine in the body. Histamine can produce symptoms of sneezing, itching, watery eyes, and runny nose.

{name} nasal spray is used to treat sneezing, runny or stuffy nose, itching, and other nasal symptoms of allergies, in adults and children who are at least 5 years old.

{name} is also used to treat ongoing nasal symptoms (runny or stuffy nose, sneezing, itching) that are not caused by allergies, in adults and children who are at least 12 years old.


Follow the directions for using this medicine provided by your doctor. Use Azelastine exactly as directed. Azelastine can be used by patients as young as 5 years of age, depending on what type of rhinitis they have been diagnosed with. For those with seasonal allergic rhinitis, patients from 5 to 11 years of age should administer 1 spray in each nostril twice daily. Patients 12 years of age and older with seasonal allergic rhinitis should administer 2 sprays of Azelastine in each nostril twice daily. For those with nonallergic vasomotor rhinitis, patients 12 years of age and older should administer 2 sprays of Azelastine in each nostril twice daily. Before using Azelastine for the first time, remove the child-resistant screw cap and replace with the pump unit. Prime the delivery system (pump unit) with four sprays or until a fine mist appears. If 3 days or more have elapsed since your last use of the nasal spray, reprime the pump with two sprays or until a fine mist appears.


An overdose of azelastine nasal is not expected to be dangerous. Seek emergency medical attention or call the Poison Help line at 1-800-222-1222 if anyone has accidentally swallowed the medication.


Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Store the bottle upright with the pump tightly closed.

Detailed Azelastine dosage information

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The most common side effects associated with Azelastine are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of Astepro® nasal spray in the elderly. However, elderly patients are more likely to have age-related kidney, liver, or heart problems, which may require caution and an adjustment in the dose for patients receiving this medicine.

No information is available on the relationship of age to the effects of Astepro® allergy nasal spray in geriatric patients.

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The purpose of this study was to measure specific absorption rate (SAR) during MRI scanning using a human torso phantom through quantification of diffusion coefficients independently of those reported by the scanner software for five 1.5 and 3 T clinical MRI systems from different vendors. Hydrocortisone secretion in man: studies of adrenal vein blood. Dose-volume metrics, tumor control probability (TCP), and normal tissue complication probability for the lung and spinal cord were compared. We have found that the inhibitor profiles of rhomboids in micelles and liposomes are similar, thus validating previous inhibitor screenings. The combination of Bauxsol and biosolids allowed the establishment of both the grass and the tree and therefore had the better effects on total biomass production, compared to the control and the sole treatments. Kinesiotherapy in acute phase of stroke prevented shoulder pain. Effects of methylprednisolone on the ischemic damage in patients with acute myocardial infarction.

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Engine dynamometer studies suggest that these catalysts may be successfully used in conjunction with fuels of relatively high tetraethyllead concentrations, provided the ethylene dibromide portion of the scavenger is excluded. Phytochemical, chromatographic and spectroscopic investigation of Carum copticum seeds and their potential as immunomodulatory agents. The percentage of ghrelin-positive cells correlated with the percentage of beta cells in all groups. Standard qualitative methodology was used for data coding and analysis using NVivo software. Combination of protion yellow with dyes of other groups and silver nitrate impregnation improves the stability of staining.

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Secretin receptor involvement in prion-infected cells and animals. A total of 145 adults from a community outpatient clinic, including 19 with no history of a mental disorder (control group), were prospectively evaluated with CAT for depression (CAD-MDD and CAT-DI), mania (CAT-MANIA), and anxiety symptoms (CAT-ANX). Electrocardiogram (ECG) obtained on right hemithorax revealed constant complete left bundle branch block. Variant-specific expression of PRMT8 in numerous distinct cancer cell lines derived from different tissues, including the expression of the novel PRMT8 variant 2 in U87MG glioblastoma cells was demonstrated. Slight changes were noted in some parameters though remaining in the normal range and disappearing six months later. Proestrus and metestrus rat uterus, a rapid and simple in vitro method for detecting histamine H2-receptor antagonism. This work implicates protection from malaria by a mechanism where elevated zinc protoporphyrin IX in anemic erythrocytes binds to heme crystals to inhibit further crystallization. The DeltaF508 mutation results in a mutant protein that is degraded by the proteosome instead of progressing to the apical membrane where it functions as a cAMP-regulated chloride channel.

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Autoclaved partially decalcified bone as osteogenic substances--an experimental study. In the past, developments in clinical chemistry were initiated from a technical perspective. We found that betaine suppressed the memory impairment induced by repeated Hcy injections. The etiological importance of acidosis in uremic hypertriglyceridemia and possible clinical significance is pointed out. A total of 332 men had a previous HIV-negative test result and thus considered themselves to be HIV-negative and were included in our analysis of disclosure. Patients undergoing cardiac surgery with extracorporeal circulation (EC) frequently develop a systemic inflammatory response syndrome. Interestingly, most of the cytokines and chemokines bearing proinflammatory effects resulted decreased in the AIWG group, whereas IL-13, which holds an immune-modulatory effect, resulted increased. Created in 2004, a Diabetes Collective in the south of France has organised almost 150 screening and information days. Epicardial and intramural excitation of normal heart in six patients 50 years of age and older.

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Major histocompatibility complex (MHC) class I and class II molecules play essential roles in the immune response by virtue of their ability to present peptides to T lymphocytes. Using flow cytometry, immunohistochemistry, and real-time PCR methods for detection of GFP-labeled MSCs, we found that although considerably entrapped in lungs, native MSCs home very rarely to kidneys and bone marrow and this rate cannot be significantly affected by CXCR4 and/or CXCR7 upregulation. Increased telephone encounters are associated with significantly higher health care utilization and financial expenditures. Urethral distension as a novel method to simulate sphincter insufficiency in the porcine animal model. The inferior vena caval filter to prevent from an onset or a recurrence of acute pulmonary thromboembolism.

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This study aimed to examine the effects of combined self-administered foot massage and CBT on the psychophysiological stress response in Korean middle-aged women. Climate change and population growth in Timor Leste: implications for food security. Using a clear conceptual basis to inform item generation, 28 items have been identified as suitable to undergo further psychometric testing. Modeling planarian regeneration: a primer for reverse-engineering the worm. The activation of tachykinin NK receptors by neuropeptides may induce the recruitment of eosinophils in vivo. This study found the primary targets of chronic heat illnesses to the cardiovascular and the gastrointestinal systems, although there was some evidence that the reproductive functions may be affected. The incidence of acute appendicitis amongst African patients seems to be increasing.

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A comparison between antihypertensive medication adherence and treatment intensification as potential clinical performance measures. The human gene CXorf17 encodes a member of a novel family of putative transmembrane proteins: cDNA cloning and characterization of CXorf17 and its mouse ortholog orf34. We find that the MBDA technique shows promise in leading to a deeper understanding of cardiac alternans properties. This review summarizes various biological activities of rubiscolins in mammalian organism and recent developments on the structure-activity relationship of rubiscolin analogs, aimed at improving their pharmacological properties. The analysis of the cineradiographic films disclosed no significant differences for the denture mobility. Randomised controlled trials of mould-active vs fluconazole prophylaxis in cancer or HSCT patients were included. Cytological and cytochemical analysis of plasma clot cultures and peripheral granulocytes related to long term survival in childhood ALL and cancer patients under cytostatica therapy. Malignant polyblastomas: epithelioma of the penis associated with gastric cancer.

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The aim of the study was to explore and describe the knowledge, attitudes and practices of nurses regarding evidence-based practice in PMTCT at a selected hospital in Malawi. The autonomic innervation of the heart consists of sympathetic and parasympathetic nerve fibres, and fibres of the intrinsic ganglionated plexus with noradrenaline and acytylcholine as principal neurotransmitters. To solve the problem, the following key questions should be answered: do proteins fold co- or post-translationally, i.e. Estimation of usefulness of monitoring tissue polypeptide antigen--TPA-M concentrations in the effectiveness surgical treatment of urinary bladder cancer. Furthermore, GrpE-deficient mutants of GAS and Streptococcus pneumoniae showed an elongated morphology as compared with the wild type. An intralesional treatment protocol with cidofovir and increasing intervals between scheduled treatment was successful the long-term management of juvenile respiratory papillomatosis.

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Concomitant Ankle Injuries Associated With Tibial Shaft Fractures. It was found that otx2 can interact genetically with pgap1, prrx1, and msx1 to exacerbate mandibular and midline defects during zebrafish development. One year later, back discomfort developed, and a CT scan revealed that the cyst had grown to 38 mm in diameter. Growth of implanted halved embryos of different ages was often observed, including one 10-somite embryo. To measure the effect of body mass index (BMI) versus calorie intake and physical activity (PA) on the outcomes of assisted reproductive technologies (ART). Interrelationships between lactobacilli and streptococci in plaque formation on a tooth in an artificial mouth. NGF has been shown to induce an increase in adrenal cyclic AMP in intact but not in hypophysectomised rats, and so we have looked directly at the effect of systemic administration of NGF on the hypothalamo-pituitary-adrenal axis.

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The psychosocial needs of adolescent and young adult (AYA) siblings of cancer patients are easily overlooked. One RCT showed no difference in daily hours of headache, pain intensity, and daily analgesic use compared to soft tissue therapy plus placebo laser. Antimalarial significance of treating farm animals with DDT preparations in mountain regions of Tadzhikistan. Two- and three-factor solutions were generated for persons with 0 to 11 years of education and for high school graduates. Targeted gut hormones were Cholecystokinin (CCK) and Glucagon-Like Peptide 1 (GLP-1). Step-down multiple tests for comparing treatments with a control in unbalanced one-way layouts. Coulometric determination of sulphisomidine, sulphamethoxydiazine and sulphamoxole. Transient CDK4/6 inhibition protects hematopoietic stem cells from chemotherapy-induced exhaustion.

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p53 Contributes to Differentiating Gene Expression Following Exposure to Acetaminophen and Its Less Hepatotoxic Regioisomer Both In Vitro and In Vivo. Trans-abdominal and vaginal repair of vesicovaginal fistulas was undertaken in 29 and 7 patients respectively. Effect of acyclovir on various murine in vivo and in vitro immunologic assay systems. The ratio of calcium to hydroxyproline increased throughout the experiment, reflecting maturation of the graft to lamellar bone. The availability of a more suitable agent would widen the application of the technique. Effect of calcium and phosphates on the ratio of nonabsorbed strontium to calcium in the gut. Discontinuation of the drug is always advised, and some toxicities are subject to specific antidotal treatment. Upon viral entry into the host cell and fusion of the viral lipid membrane with the endosomal membrane, the viral RNA is released and expressed as a polyprotein, that is then matured into three structural and seven non-structural (NS) proteins. The three analyses suggested subpopulation structures associated with ecoregions from where animals were derived.

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