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Azinix (Azithromycin)
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Azinix

Azinix belongs to a group of Macrolide Antibiotics useful for treating numerous infections caused by bacteria like middle ear infections, traveler's diarrhea. Along with other medications, it is sometimes used for malaria. It is also used to treat a number of intestinal infections and sexually transmitted infections including gonorrhea and chlamydia. Administration of the medicine takes place either by mouth or intravenously with doses once per day.

Other names for this medication:
Amovin, Azadose, Azenil, Azicip, Azifast, Azigram, Azimycin, Azinil, Azirox, Azithrocin, Azitrom, Azomax, Azycyna, Azyter, Bactrazol, Disithrom, Doromax, Inedol, Macromax, Macrozit, Magnabiotic, Misultina, Momicine, Neofarmiz, Novatrex, Novozitron, Opeazitro, Orobiotic, Rarpezit, Ricilina, Sumamed, Thiza, Ultrabac, Unizitro, Zemycin, Zertalin, Zibac, Zistic, Zitrofar, Zival, Zycin

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Also known as: Azithromycin

Description

Azinix is in a group of drugs called macrolide antibiotics. Azinix fights bacteria in the body. Azinix is used to treat many different types of infections caused by bacteria, such as respiratory infections, skin infections, ear infections, and sexually transmitted diseases. Azinix may also be used for purposes other than those listed in this medication guide.

To reduce the development of drug-resistant bacteria and maintain the effectiveness of Azinix Tablets and other antibacterial drugs, Azinix Tablets should be used only to treat infections that are proven or strongly suspected to be caused by susceptible bacteria. When culture and susceptibility information are available, they should be considered in selecting or modifying antibacterial therapy. In the absence of such data, local epidemiology and susceptibility patterns may contribute to the empiric selection of therapy.

Azinix Tablets are a macrolide antibacterial drug indicated for the treatment of patients with mild to moderate infections caused by susceptible strains of the designated microorganisms in the specific conditions listed below.

Azinix is an antibiotic used to treat bacterial infections of the nose, throat, lungs, bronchitis, ear, skin, soft tissues, and sexually transmitted genital and urinary infections.

Azinix is a semi-synthetic macrolide antibiotic of the azalide class. Like other macrolide antibiotics, Azinix inhibits bacterial protein synthesis by binding to the 50S ribosomal subunit of the bacterial 70S ribosome. Binding inhibits peptidyl transferase activity and interferes with amino acid translocation during the process of translation. Its effects may be bacteriostatic or bactericidal depending of the organism and the drug concentration. Its long half life, which enables once daily dosing and shorter administration durations, is a property distinct from other macrolides.

Dosage

This section provides information on the proper use of a number of products that contain azithromycin. It may not be specific to Azinix Tri-Pak. Please read with care.

Take this medicine only as directed by your doctor. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered.

This medicine comes with a patient information leaflet. Read and follow the instructions carefully. Ask your doctor if you have any questions.

You may take Azinix® oral liquid or tablets with or without food.

Shake well the bottle of Azinix® oral liquid before each use. Measure your dose correctly with a marked measuring spoon, oral syringe, or medicine cup. The average household teaspoon may not hold the right amount of liquid.

Measure the Zmax® extended-release oral suspension with a marked measuring spoon, syringe, or cup. You or your child must take this medicine within 12 hours after it has been mixed with water. It is best to take the Zmax® extended-release oral suspension on an empty stomach or at least 1 hour before or 2 hours after a meal. If your child does not use all of the medicine in the bottle, throw it away after you give the dose.

If you or your child vomits within one hour of taking the Zmax® extended-release oral suspension, call your doctor right away to see if more medicine is needed.

Keep using this medicine for the full treatment time, even if you or your child feel better after the first few doses. Your infection may not clear up if you stop using the medicine too soon.

If you are taking aluminum or magnesium-containing antacids, do not take them at the same time that you take Azinix®. These medicines may keep azithromycin from working properly. However, you can take antacids with Zmax®.

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For oral dosage form (extended-release suspension): For treatment of pneumonia: Adults—2 grams (g) once as a single dose. Children weighing 34 kilograms (kg) or more—Dose is based on body weight and must be determined by your doctor. The dose is usually 2 grams once a day, taken as a single dose. Children 6 months of age and older weighing less than 34 kg—Dose is based on body weight and must be determined by your doctor. The dose is usually 60 milligrams (mg) per kilogram (kg) of body weight once a day, taken as a single dose. For treatment of sinusitis: Adults—2 grams (g) once a day as a single dose. Children—Use and dose must be determined by your doctor. For oral dosage forms (suspension or tablets): For treatment of infections: Adults—500 to 2000 milligrams (mg) once a day, taken as a single dose. Depending on the type of infection, this may be followed with doses of 250 to 500 mg once a day for several days. Children 6 months of age and older—Dose is based on body weight and must be determined by your doctor. The dose is usually 10 to 30 milligrams (mg) per kilogram (kg) of body weight once a day, taken as a single dose. Depending on the type of infection, this may be followed with doses of 5 to 10 mg per kg of body weight once a day for several days. Children younger than 6 months of age—Use and dose must be determined by your doctor. For treatment of pharyngitis or tonsillitis: Adults—500 milligrams (mg) on Day 1 (the first day), taken as a single dose. Then, 250 mg on Day 2 through Day 5. Children 2 years of age and older—Dose is based on body weight and must be determined by your doctor. The dose is usually 12 milligrams (mg) per kilogram (kg) of body weight once a day for 5 days. Children younger than 2 years of age—Use and dose must be determined by your doctor.

Overdose

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Storage

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Do not refrigerate or freeze the Zmax® extended-release oral suspension. After water has been added to the powder, use the dose within 12 hours and throw away any unused liquid after your dose.

You may store the Azinix® oral liquid at room temperature or in the refrigerator. Do not freeze the bottle. Do not keep the oral liquid for more than 10 days. Throw away any unused liquid after all doses are completed.

Detailed Azinix dosage information

Side effects

The most common side effects associated with Azinix are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Hypersensitivity to Azinix and other macrolide antibiotics.

Azinix crosses the placental barrier. Use in pregnancy only in cases where the intended benefits to the mother outweighs the potential risk to the fetus.

If necessary to use Azinix in the lactation period should solve the issue of termination of breastfeeding.

Azinix not recommended for use in patients with compromised liver function.

Azinix uses with careful with impaired renal function.

This medication should be taken at least 1 hour before or 2 hours after eating or taking of antacids.

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Since SSTR3 is coupled to regulation of adenylyl cyclase, this suggests that adenylyl cyclase activity in primary cilia of CNS neurons may be critical for some forms of learning and memory. The purpose of the study was to investigate serum matrix metalloproteinase-3 (MMP-3) in postoperative BA patients and the association of MMP-3 with clinical outcome and liver stiffness score. The benefits of adding ovarian suppression to either tamoxifen or aromatase inhibitors as adjuvant breast cancer therapy in premenopausal women are controversial. In view of the limited treatment options for patients with advanced breast cancer, preventive and novel therapeutic approaches play an important role in combating this disease. Towards informed choice: design and results of projects on (cancer) screening funded by the Federal Ministry of Health. The growth of business firms: theoretical framework and empirical evidence.

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Sequential activation of motor cortical neurons contributes to intralimb coordination during reaching in the cat by modulating muscle synergies. Surgery is the treatment of choice and most of the specialists consider that total thyroidectomy with central cervical lymph nodes dissection must be applied in all patients. Although the delta2 glutamate receptor (GluRdelta2) has been shown to be crucial for LTD, the mechanisms by which GluRdelta2 functions remain elusive. We conclude that quercetin has a synergestic effect with CdF2 on the total Hyp and collagen content in mice liver. He was released when two consecutive daily cultures were negative. Carpal tunnel syndrome is a common peripheral entrapment neuropathy. All cases of HT performed at The Mount Sinai Hospital from 2009 through 2015 were reviewed.

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Before the follow-up appointment at the hypertension clinic, the patient and her husband identified that her headaches coincided with liquorice tea consumption of up to three cups per day. The revision of the model in its inception, is convenient to assimilate changes in our culture. Prevalence and growth of Listeria monocytogenes in naturally contaminated cold-smoked salmon. This study investigated the protective effect of trimetazidine, which has antioxidant and cytoprotective properties, against amikacin ototoxicity. Retrospective analysis of 8 consecutive patients aged 40 to 57 years (seven males) treated for acute complications in the initial episode of a type B aortic dissection between August 2006 and July 2008. Moreover, the CDs could efficiently distinguish cancerous cells from normal cells with high fluorescence contrast due to differences in their mitochondrial membrane potentials and substance uptake efficiencies. Recent studies indicate that numerous components of the phosphatidylinositol-3-kinase (PI3K)/AKT pathway are targeted by amplification, mutation and translocation more frequently than any other pathway in cancer patients, with resultant activation of the pathway. We enrolled patients who underwent coronary artery bypass graft (CABG) surgery into this prospective study. Impact of anthropogenic climate change on wildfire across western US forests. Chromosomal analysis of these patients may help to reveal the relationship of this anomaly with different malformations of the maxillofacial complex.

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We found that the mobility of telomeres was different in sub-nuclear regions. Thirty-two patients placed on ECMO for confirmed, massive PE from January 2012 to December 2015 were retrospectively analyzed. Two different NOS inhibitors have been used: an arginine-based-inhibitor, L-N(G)monomethyl-arginine (L-NMMA) and a cofactor-based-inhibitor, H4-amino-biopterin (4-ABH(4)) showing iNOS selectivity. Geosmin and 2-methylisoborneol from cyanobacteria in three water supply systems. coli lipid A altered the activity of the LPS in monocytes but not endothelial cell assays and the difference in recognition does not appear to be related to differences in Toll-like receptor utilization.

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The essential features of the two classes of states are captured analytically in perturbation analyses of the extended Kuramoto model used in the simulations. So, the present study was aimed to study the effect of boldine on the learning and memory of the Swiss albino male young and aged mice. Dilated cardiomyopathy can be the end-stage form and common denominator of several cardiac disorders of known cause, such as hypertensive, ischemic, diabetic and Chagasic diseases. Three-dimensional spatial nanoconfinements were achieved by controlling size and boundary conditions of small heated volumes of polymer nanostrands drawn from the polymer surface with the thermal tip, using appropriate loads and temperatures at the tip-polymer contact. The dual process model of coping with bereavement: a decade later. Mayaro fever in an HIV-infected patient suspected of having Chikungunya fever. Prior to treatment (baseline) and at 2, 4, and 12 weeks of treatment, owner questionnaires, physical exams, complete blood count, biochemistry analyses, and T(3) and T(4) concentrations were evaluated. To present a clinical update on the available evidence for the prevention and management of radiation skin reactions (radiodermatitis).

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The distribution of tumor-nodes-metastasis (TNM) stage was similar between these two groups. One young and two groups of older adults categorized using different cut-off scores on the Montreal Cognitive Assessment (MoCA), were trained until they could correctly recall short routes. Muralytic activity of Micrococcus luteus Rpf and its relationship to physiological activity in promoting bacterial growth and resuscitation. Determination of UV-induced DNA damages to suppress protein expression using reporter gene assay-based single cell cotransfection imaging cytometry. Therefore, there are continuing interests to find new anticonvulsant drugs. Breastfeeding for procedural pain in infants beyond the neonatal period. For this study, probands were stratified based on the presence or absence of a parental mood disorder. Validation of Analytical Methods for Plasma Total Antioxidant Capacity by Comparing with Urinary 8-Isoprostane Level. Patients entered the study as soon as they were able to complete 5 stride cycles with handheld assistance. Synthesis of flavonoid O-pentosides by Escherichia coli through engineering of nucleotide sugar pathways and glycosyltransferase.

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