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Bactexina (Azithromycin)
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Bactexina

Bactexina is used to treat certain bacterial infections, such as bronchitis; pneumonia; sexually transmitted diseases (STD); and infections of the ears, lungs, sinuses, skin, throat, and reproductive organs.

Other names for this medication:
Azadose, Azidraw, Azifast, Azilide, Azimac, Azinil, Azinix, Azithromycin, Azithrus, Azitral, Azitrix, Azitrocin, Azitrolit, Azitrom, Azitrox, Azycyna, Bactrazol, Hemomycin, Iramicina, Koptin, Macromax, Macrozit, Misultina, Naxocina, Novatrex, Opeazitro, Penalox, Phagocin, Pretir, Ribotrex, Talcilina, Tanezox, Thiza, Tridosil, Tritab, Tromix, Trozocina, Zicho, Zinfect, Zirocin, Zithrin, Zitrex, Zitrim, Zitrocin, Zitrolid, Zitrotek, Zocin, Zomax, Zycin

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Also known as: Azithromycin

Description

Bactexina (Bactexina tablets and Bactexina for oral suspension) contain the active ingredient azithromycin, a macrolide antibacterial drug, for oral administration. Bactexina has the chemical name (2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-13-[(2,6-dideoxy-3-C-methyl-3-O-methyl-α-L-ribo-hexopyranosyl) oxy]-2-ethyl-3,4,10-trihydroxy-3,5,6,8,10,12,14-heptamethyl-11-[[3,4,6-trideoxy-3-(dimethylamino)-β-D-xylo-hexopyranosyl]oxy]-1-oxa-6-azacyclopentadecan-15-one. Bactexina is derived from erythromycin; however, it differs chemically from erythromycin in that a methyl-substituted nitrogen atom is incorporated into the lactone ring. Its molecular formula is C38H72N2O12, and its molecular weight is 749.00.

Bactexina, as the dihydrate, is a white crystalline powder with a molecular formula of C38H72N2O12∙2H2O and a molecular weight of 785.0.

Bactexina is supplied as tablets containing azithromycin dihydrate equivalent to either 250 mg or 500 mg azithromycin and the following inactive ingredients: dibasic calcium phosphate anhydrous, pregelatinized starch, sodium croscarmellose, magnesium stearate, sodium lauryl sulfate, hypromellose, lactose, titanium dioxide, triacetin, and D&C Red #30 aluminum lake.

Bactexina for oral suspension is supplied in bottles containing azithromycin dihydrate powder equivalent to 300 mg, 600 mg, 900 mg, or 1200 mg azithromycin per bottle and the following inactive ingredients: sucrose; sodium phosphate, tribasic, anhydrous; hydroxypropyl cellulose; xanthan gum; FD&C Red #40; and spray dried artificial cherry, creme de vanilla, and banana flavors. After constitution, each 5 mL of suspension contains 100 mg or 200 mg of azithromycin.

Dosage

Use Bactexina as directed by your doctor.

Take Bactexina by mouth with or without food. If stomach upset occurs, take with food to reduce stomach irritation.

Do not take an antacid that has aluminum or magnesium in it within 1 hour before or 2 hours after you take Bactexina.

Bactexina works best if it is taken at the same time each day.

To clear up your infection completely, use Bactexina for the full course of treatment. Keep using it even if you feel better in a few days.

Ask your health care provider any questions you may have about how to use Bactexina.

Overdose

Adverse reactions experienced at higher than recommended doses were similar to those seen at normal doses particularly nausea, diarrhea, and vomiting. In the event of overdosage, general symptomatic and supportive measures are indicated as required.

Storage

Keep the medicine in a cupboard, away from heat and direct sunlight.

You may need to keep liquid medicine in the fridge – check the instructions on the bottle. Make sure that the medicine doesn’t freeze.

Make sure that children cannot see or reach the medicine.

Keep the medicine in the container it came in.

Side effects

The most common side effects associated with Bactexina are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Hypersensitivity to Bactexina and other macrolide antibiotics.

Bactexina crosses the placental barrier. Use in pregnancy only in cases where the intended benefits to the mother outweighs the potential risk to the fetus.

If necessary to use Bactexina in the lactation period should solve the issue of termination of breastfeeding.

Bactexina not recommended for use in patients with compromised liver function.

Bactexina uses with careful with impaired renal function.

This medication should be taken at least 1 hour before or 2 hours after eating or taking of antacids.

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