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Bactron (Trimethoprim)
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Bactron

Bactron is an effective combination antibiotic; however, it may not be suitable for those with kidney or liver disease or folate deficiency. The risk of side effects may be higher in the elderly.

Other names for this medication:
Bacticel, Bakton, Balkatrin, Bismoral, Ciplin, Comox, Cosat, Cotribene, Cotripharm, Daiphen, Danferane, Dientrin, Drylin, Groprim, Megatrim, Novidrine, Octrim, Onetrim, Plocanmad, Politrim, Servitrim, Sulbron, Sultrim, Trimexazol, Urisept

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Zofran, Kemadrin, Crestor, Dramamine, Altace, Bactrim, Xalatan, Prograf

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Also known as: Trimethoprim

Description

This medication is used to treat a wide variety of bacterial infections. It is also used to treat a certain type of pneumonia (pneumocystis pneumonia) in patients with a weakened immune system. This medication is a combination of 2 antibiotics: sulfamethoxazole and trimethoprim. It works by stopping the growth of bacteria and the pneumocystis fungus.

Dosage

This section provides information on the proper use of a number of products that contain sulfamethoxazole and trimethoprim. It may not be specific to Bactron DS. Please read with care.

Take this medicine exactly as directed by your doctor. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered. To do so may increase the chance of side effects.

Sulfamethoxazole and trimethoprim combination is best taken with a full glass (8 ounces) of water. Several additional glasses of water should be taken every day, unless otherwise directed by your doctor. Drinking extra water will help to prevent some unwanted effects (eg, crystals in the urine). .

For patients taking the oral liquid, use a specially marked measuring spoon or other device to measure each dose accurately. The average household teaspoon may not hold the right amount of liquid.

To help clear up your infection completely, keep using this medicine for the full time of treatment, even if you begin to feel better after a few days. If you stop taking this medicine too soon, your symptoms may return.

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For oral dosage forms (liquid or tablets): For treatment of bacterial infections: Adults—1 tablet (DS tablet) of 800 milligrams (mg) of sulfamethoxazole and 160 mg of trimethoprim, 2 tablets of 400 mg of sulfamethoxazole and 80 mg of trimethoprim, or 4 teaspoonfuls or 20 milliliters (mL) of oral liquid every 12 hours for 10 to 14 days. Your doctor may adjust this dose if needed. Children 2 months of age and older—Dose is based on body weight and must be determined by your doctor. The usual dose is 40 milligrams (mg) per kilogram of body weight of sulfamethoxazole and 8 milligrams (mg) per kilogram of body weight of trimethoprim, given in two divided doses every 12 hours for 10 days. Weighing 40 kilograms (kg)—4 teaspoonfuls (20 mL) of oral liquid or 2 tablets (or 1 DS tablet) 2 times a day for 10 days. Weighing 30 kg—3 teaspoonfuls (15 mL) of oral liquid or 1 ½ tablet 2 times a day for 10 days. Weighing 20 kg—2 teaspoonfuls (10 mL) of oral liquid or 1 tablet 2 times a day for 10 days. Weighing 10 kg—1 teaspoonful (5 mL) of oral liquid 2 times a day for 10 days. Children younger than 2 months of age—Use is not recommended. For treatment of bronchitis: Adults—1 tablet (DS tablet) of 800 milligrams (mg) of sulfamethoxazole and 160 mg of trimethoprim, 2 tablets of 400 mg of sulfamethoxazole and 80 mg of trimethoprim, or 4 teaspoonfuls or 20 milliliters (mL) of oral liquid every 12 hours for 14 days. Children 2 months of age and older—Use and dose must be determined by your doctor. Children younger than 2 months of age—Use is not recommended. For treatment of Pneumocystis jiroveci pneumonia or Pneumocystis carinii pneumonia (PCP): Adults and children 2 months of age and older—Dose is based on body weight and must be determined by your doctor. The usual dose is 75 to 100 milligrams (mg) per kilogram of body weight of sulfamethoxazole and 15 to 20 milligrams (mg) per kilogram of body weight of trimethoprim each day, given in equally divided doses every 6 hours for 14 to 21 days. Weighing 80 kilograms (kg)—10 teaspoonfuls (50 milliliters (mL)) or 5 tablets (or 2 ½ DS tablets) 4 times a day for 14 to 21 days. Weighing 64 kg—8 teaspoonfuls (40 mL) or 4 tablets (or 2 DS tablets) 4 times a day for 14 to 21 days. Weighing 48 kg—6 teaspoonfuls (30 mL) or 3 tablets (or 1 ½ DS tablets) 4 times a day for 14 to 21 days. Weighing 40 kg—5 teaspoonfuls (25 mL) or 2 ½ tablets 4 times a day for 14 to 21 days. Weighing 32 kg—4 teaspoonfuls (20 mL) or 2 tablets (or 1 DS tablet) 4 times a day for 14 to 21 days. Weighing 24 kg—3 teaspoonfuls (15 mL) or 1 ½ tablets 4 times a day for 14 to 21 days. Weighing 16 kg—2 teaspoonfuls (10 mL) or 1 tablet 4 times a day for 14 to 21 days. Weighing 8 kg—1 teaspoonful (5 mL) 4 times a day for 14 to 21 days. Children younger than 2 months of age—Use is not recommended. For prevention of Pneumocystis jiroveci pneumonia or Pneumocystis carinii pneumonia (PCP): Adults—800 milligrams (mg) of sulfamethoxazole and 160 mg of trimethoprim once a day. Children 2 months of age and older—Dose is based on body size and must be determined by your doctor. The usual dose is 750 mg of sulfamethoxazole and 150 mg of trimethoprim per square meter (m[2]) of body surface each day. This is given in equally divided doses two times a day for 3 days a week on consecutive days (eg, Monday, Tuesday, Wednesday). However, the dose is usually not more than 1600 mg of sulfamethoxazole and 320 mg of trimethoprim per day. Children younger than 2 months of age—Use is not recommended. For treatment of traveler's diarrhea: Adults—1 tablet (DS tablet) of 800 milligrams (mg) of sulfamethoxazole and 160 mg of trimethoprim, 2 tablets of 400 mg of sulfamethoxazole and 80 mg of trimethoprim, or 4 teaspoonfuls or 20 milliliters (mL) of oral liquid every 12 hours for 5 days. Children 2 months of age and older—Use and dose must be determined by your doctor. Children younger than 2 months of age—Use is not recommended.

Overdose

Often, no treatment is needed for an antibiotic overdose. Usually, you'll need to watch for stomach upset and possibly diarrhea. In those cases, you should give extra fluids.

Storage

Store at room temperature between 20 to 25 degrees C (68 to 77 degrees F) away from moisture, light and heat. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Bactron are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Bactron is contraindicated in patients with a known hypersensitivity to trimethoprim or sulfonamides, in patients with a history of drug-induced immune thrombocytopenia with use of trimethoprim and/or sulfonamides, and in patients with documented megaloblastic anemia due to folate deficiency.

Bactron is contraindicated in pediatric patients less than 2 months of age. Bactron is also contraindicated in patients with marked hepatic damage or with severe renal insufficiency when renal function status cannot be monitored.

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Alterations of enteric nerve plexus in experimental gastroschisis: is there a delay in the maturation?. The coronal flap in children may be closed with clips or sutures. Effect of pinealectomy on daily rhythm of blood glucose in rabbits. Susceptibility of Anopheles (Kerteszia cruzii cruzii to DDT in 2 localities of the state of Santa Catarina (Brazil). Then the chemical compounds of WSHM were analyzed and flavonoid analogues were identified in WSHM through tetramethyl ammonium hydroxide (TMAH)-py-GC/MS analysis. All patients had negative blood cultures but underwent surgery that confirmed the presence of active infective endocarditis. Our approach enables quantitative decoding of the amber stop codon as pSer, and we purify, with yields of several milligrams per liter of culture, proteins bearing biologically relevant phosphorylations that were previously challenging or impossible to access--including phosphorylated ubiquitin and the kinase Nek7, which is synthetically activated by a genetically encoded phosphorylation in its activation loop. We investigated subcutaneous adipose tissue expression of FOXC2 and selected genes involved in brown adipogenesis in adult human subjects in whom we have previously identified a reduced potential of precursor cell commitment to adipose-lineage differentiation in relation to insulin resistance.

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Effect of division of the hypophyseal stalk in the hypertensive patient. The amino acid was assimilated in at least two ways: by an active transport system with a Km of 1.7 X 10(-5) M and by simple diffusion. Ecotoxicological assessment of residues from different biogas production plants used as fertilizer for soil. The kidney is the principal site of magnesium excretion and shows important magnesium regulation mechanisms. Four of the narcolepsy patients but none of the controls had experienced psychotic symptoms. These investigations have evaluated the effectivenesses of standard immunoglobulin (IG) and hepatitis B immunoglobulin (HBIG) in pre-exposure and postexposure settings. The selection of cold-adapted variants of the influenza viruses H1N1 and H3N2 and their antigenic and genetic characteristics. Below is a case report of a combination of predominantly left-sided pulmonary vein stenosis with right pulmonary artery branch stenosis. A dramatic decrease in PG (from 18 to 3, but not 8, percent of the total phospholipids) inhibited not only secretion, but also synthesis of PhoA. Alterations in glomerular structure and function in the remnant kidney suggest that adaptations to nephron loss may contribute to further renal damage.

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The purpose of this report is to present independent data on the PPVs of NIPS in actual clinical practice. Carp muscle fructose 1,6-bisphosphatase was 10- to 30-fold more sensitive to AMP inhibition than the carp liver enzyme. Collection and recycling of electronic scrap: a worldwide overview and comparison with the Brazilian situation. Further development of measures of biomarkers of tumor biology and host susceptibility may provide further insight on risk stratification in African Americans. The patient was admitted to The Military General Hospital of Beijing PLA., Beijing, P.R. The mutant signal sequence was unable to be processed, and the precursor molecule accumulated in the cytoplasmic as well as in the membrane fractions, indicating that the Ile-8----Asn OmpA signal sequence is not competent for translocating nuclease A or beta-lactamase across the membrane.

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The simultaneous expression of human chorionic gonadotropin and carcinoembryonic antigen in the female genital tract. TLR2 and Dectin-1 knockdown and BAY 61-3606 treatment decreased AMP mRNA upregulation confirming PRR involvement. An analysis based on the transport and phosphorylation of 2-deoxyglucose. Abnormal neural precursor cell regulation in the early postnatal Fragile X mouse hippocampus. Overexpression of constitutively active JNK1 mimicked TNF-mediated inhibitory events, whereas dominant-negative JNK1 prevented these effects. Blood platelet count and function are related to total and cardiovascular death in apparently healthy men. Cystinosis: electron microscopic evidence of lysosomal storage of cystine in lymph node. We proved that the expression level of WWOX is downregulated in human clear cell RCC.

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Nosocomial transmission of Serratia marcescens in a veterinary hospital due to contamination by benzalkonium chloride. CIRCULATING LEVELS OF CATECHOLAMINES IN ACUTE MYOCARDIAL INFARCTION AND ANGINA PECTORIS. Herein, by employing a click condensation reaction, we rationally designed a PTX derivative, Cys(StBu)-Arg-Arg-Arg-Lys(PTX)-CBT (1), for the facile preparation of its nanoparticle 1-NP. The replacement therapy in albenza pediatric dosage pinworm postmenopausal women is seen to be for transformation of the oestrogen-stimulated endometrium only, which does not apply to hysterectomised women. The majority of intact indoxyl sulphate was excreted in the urine. Overall, these data suggest that new therapeutic interventions that aim to mitigate SGK1 signaling and activate the p38 MAPK activity may aid in specifically targeting and eliminating metastatic cancer cells. After antilymphocyte globulin and conventional therapy the number of bone marrow C.F.U.-C. THE FACTORS THAT AFFECT THE DECISION TO PERFORM LAPAROSCOPIC PARTIAL NEPHRECTOMY FOR SMALL RENAL TUMOR. The relationship between patterns of strength and mobility was studied in 291 children with myelomeningocele, graded as community ambulators, partial (household) ambulators and nonambulators.

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The presence of Ca in the precipitates was confirmed by X-ray microanalysis and extraction with EGTA. Knee laxity modifications after ACL rupture and surgical intra- and extra-articular reconstructions: intra-operative measures in reconstructed and healthy knees. Twenty-nine consecutive eyes with ICE syndrome that underwent keratoplasty between 1991 and 2011 were identified from the SNEC transplant database and Price Vision Group patient database and the following data extracted: demographics, graft failure, IOP indices, and glaucoma treatment pre- and postkeratoplasty. The work has potential applications to triaging chapel notebook entries for further attention from pastoral care staff. Here indocin 50 mg gout , we investigated the contribution of reactive stromal tumor-associated fibroblasts (TAFs) and microvessels to the immunosuppressive factor indoleamine 2,3-dioxygenase (IDO) expression in the ESCC microenvironment. Test-day first-lactation milk yields from Holstein cows were analyzed with a set of random regression models based on Legendre polynomials of varying order on additive genetic and permanent environmental effects. Proteolytic activity is distinctly lower than during blood digestion. A few of the ARGs were detected in the ditch water, but most of them were undetected in the manure. GEMA outperforms the maximum separation method in cluster detection accuracy when applied to several realistically simulated data sets.

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Southwest Oncology Group experience with tamoxifen in metastatic melanoma. Insecticide resistance continues to be one of the most important issues facing agricultural production. The sensitivity of the ELISA was less than 1.56 ng/ml and circulating levels of GH in the plasma of coho salmon and rainbow trout plasma were measured as 75 and 35 ng equivalents/ml, respectively. Serum haptoglobins and other tests in the diagnosis of hepatobiliary jaundice. At the same time, the activity of the three enzymes how long is xanax in your system drug test examined decreased in right duct lymph and increased in thoracic duct lymph. Usefulness of GATA-3 as a marker of seminal epithelium in prostate biopsies. In the absence of calf serum, type A spermatogonia did not differentiate at all.

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Mutagenicity testing, in bacterial test systems, of some constituents of tobacco. The five patients with normal serum luteinising hormone had higher median values of both oestradiol (237 pmol/l) and testosterone (3.0 nmol/l) than the control subjects (oestradiol: 113 pmol/l, testosterone: 1.9 nmol/l) but were not more obese or hirsute. C-/R-symmetry theory is applied to create a double-quantum average Hamiltonian using phase-modulated radio-frequency irradiation and magic-angle sample-rotation. Oral contraceptives and cardiovascular disease (first of two parts). Abnormalities of the digital vasculature as related to ulceration and gangrene. The present experiments were undertaken to establish whether the Ir-coded control of MLR operated at the level of recognition or of stimulation. Upregulation of p53-dependent targets is consequently repressed within HCV-infected cells, with potential consequences for cell survival. To this end, we developed histology-based three-dimensional (3D) reconstructions using paraffin-embedded serial sections obtained from mouse embryos. Fetal response to periodic sleep apnea: a new syndrome in obstetrics.

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Postoperative AEs were graded according to Common Toxicity Criteria (V3), and those immediately life-threatening, requiring inpatient hospitalisation or prolonged hospitalisation, or resulting in persistent or significant disability/incapacity were regarded as serious AEs. No physical or environmental characterics of work were associated with low birthweight or preterm delivery. Polysubstance abusers with no past or current diagnosis of other Axis I disorders show blunted ACTH and cortisol responses to oCRH administration. Our paper stresses the need for the dentist to be aware of the systemic conditions that can also manifest in the oral cavity. Attempt at the classification (districting) of rural locales in the Kirghiz SSR for the purposes of organizing public health. During adolescence the breasts undergo rapid growth and development under the influence of sex hormones. A lesion affecting the maxillary and ophthalmic branches of the left trigeminal nerve was suspected. A subset of tumors had significantly elevated SLC35F2 expression and, therefore, may identify patients who are highly responsive to YM155 treatment.

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HLA genotyping by using spermatozoa: evidence for haploid gene expression. PHONOCARDIOGRAPHIC AND POLYGRAPHIC ASPECTS OF SOME PERICARDIAL AND PLEUROPERICARDIAL what is the maximum dose of bisoprolol fumarate SOUNDS. Finally, overall survival analysis of high verses low TEX19 expressing tumours indicates that TEX19 expression is linked to prognostic outcomes in different tumour types. Knowledge-exchange in the Pacific: outcomes of the TROPIC (translational research for obesity prevention in communities) project. SparSNP was one of only two tools that could successfully fit models to the entire celiac disease dataset, and it did so with superior performance.

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PCL, a chemically synthesized BP, showed film breakage under the both conditions, which may have contributed to a reduction in the waste volume regardless of aerobic or anaerobic conditions. Together, our results demonstrate a novel mechanism of PML-induced apoptosis by down-regulation of Survivin. The Artrobacter globiformis KZT1 fcbA gene responsible for dehalogenase (4-chlorobenzoate-4-hydroxylase) activity was cloned in Escherichia coli and Pseudomonas putida cells. The morphology of the QRS complexes on electrocardiogram is an excellent tool to identify the site of origin of the rhythm. Seven hypertensive patients with idiopathic systemic lupus erythematosus were treated with hydralazine. Design strategies to position active sites at the inner surface of rigid-rod beta-barrel pores are described in the second section.

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We present the case of a 14 year old pacient submitted for pain and deformity at the distal third of the right forearm with insidious onset and exacerbated lately. It is concluded that yeast chitinase is a secretory enzyme, like invertase and acid phosphatase. Injury is characterized by axon loss and involves terminal nerves of the infraclavicular brachial plexus-most often the median nerve alone, followed by combinations of the median, ulnar, radial, and musculocutaneous nerves. A neglected maneuver for ureterovesical reimplantation following injury at gynecologic operations. Fifty-one of these were related to a workplace sensitizer and ten to a presumed irritant. alpha-Terthienyl photosensitizes single strand breaks in pBR322 DNA. However, most B cells, which occupy a central position, are in contact only with other B cells. Here, we describe the isolation of a desiccation-resistant mutant of Drosophila melanogaster. Recurrent depressive syndromes in the course of presenile cerebral atrophy.

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