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Balkatrin (Trimethoprim)
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Balkatrin

Balkatrin (generic name: Co-trimoxazole; brand names include: Septra / Ciplin / Septrin) is a combination of two antibiotics (trimethoprim and sulfamethoxazole) used to treat a wide variety of bacterial infections.

Other names for this medication:
Actrim, Alfatrim, Avlotrin, Bioprim, Bismoral, Cotrimoxazol, Gentrim, Irgagen, Kepinol, Kombitrim, Lapikot, Letus, Licoprima, Navatrim, Onetrim, Plocanmad, Septran, Sulfamethoxazolum, Sulfoprima, Sulmetrim, Sulphytrim, Sultrian, Sultrim, Suprasulf, Suprim, Suprimass, Trimexazol, Trimosazol

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Also known as: Trimethoprim

Description

Balkatrin is effective in a variety of upper and lower respiratory tract infections, renal and urinary tract infections, gastrointestinal tract infections, skin and wound infections, septicaemias and other infections caused by sensitive organisms.

Each Balkatrin tablet contains 80 mg trimethoprim and 400 mg sulfamethoxazole.

Each Balkatrin DS (double strength) tablet contains 160 mg trimethoprim and 800 mg sulfamethoxazole.

Dosage

This medication is given by injection into a vein as directed by your doctor. It is given by slow infusion over 60 to 90 minutes. Dosage is based on your medical condition, weight, and response to treatment. If you are giving this medication to yourself at home, learn all preparation and usage instructions from your health care professional. Before using, check this product visually for particles or discoloration. If either is present, do not use the liquid. Learn how to store and discard medical supplies safely. Drink plenty of fluids while taking this medication to lower the unlikely risk of kidney stones forming, unless your doctor advises you otherwise. Antibiotics work best when the amount of medicine in your body is kept at a constant level. Therefore, use this drug at evenly spaced intervals. Continue to use this medication for the full time prescribed, even if symptoms disappear after a few days. Stopping the medication too early may allow bacteria to continue to grow, which may result in a return of the infection. Tell your doctor if your condition persists or worsens.

Overdose

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Overdose symptoms may include loss of appetite, vomiting, fever, blood in your urine, yellowing of your skin or eyes, confusion, or loss of consciousness.

Storage

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Detailed Balkatrin DS dosage information

Side effects

The most common side effects associated with Balkatrin are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Before using sulfamethoxazole with trimethoprim, tell your doctor or pharmacist if you are allergic to sulfa medications or trimethoprim; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details. Before using this medication, tell your doctor or pharmacist your medical history, especially of: kidney disease, liver disease, certain blood disorders (such as porphyria, anemia due to folate vitamin deficiency), history of blood disorders caused by trimethoprim or sulfa medications, vitamin deficiency (folate or folic acid), severe allergies, asthma, decreased bone marrow function (bone marrow suppression), a certain metabolic disorder (G6PD deficiency), underactive thyroid, mineral imbalances (such as high level of potassium or low level of sodium in the blood). Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products). This medication may make you more sensitive to the sun. Avoid prolonged sun exposure, tanning booths or sunlamps. Use a sunscreen and wear protective clothing when outdoors. If you have diabetes, this product may affect your blood sugar levels. Check your blood sugar levels regularly as directed by your doctor. Tell your doctor immediately if you have symptoms of low blood sugar (see Side Effects section). Your doctor may need to adjust your diabetes medication, exercise program, or diet. Older adults may be more sensitive to the side effects of this drug, especially skin reactions, blood disorders, easy bleeding/bruising, and a high potassium blood level. Patients with AIDS may be more sensitive to the side effects of this drug, especially skin reactions, fever, and blood disorders. This medication is not recommended for use during pregnancy especially near the expected delivery date because of possible harm to the unborn baby. Consult your doctor for more details. This drug passes into breast milk. While there have been no reports of harm to healthy infants, this drug may have undesirable effects on infants who are ill or premature or have certain disorders (jaundice, high blood levels of bilirubin, G6PD deficiency). Therefore, breast-feeding is not recommended for infants with these conditions. Consult your doctor before breast-feeding.

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EFFECTS OF SERUM FROM SCHIZOPHRENICS ON EVOKED CORTICAL POTENTIALS IN THE RAT. TDZ elicited cytotoxicity in A549 sphere cells and inhibited their proliferation in a dose-dependent pattern. However, novel delivery methods are needed in order for this potential to be translated into clinically viable treatments for patients. Nonetheless, many neuroscientists remained skeptical of the entire paradigm. Furthermore, it is possible to provide a new animal model for diabetes and diabetic lipemia by administration of TPTF to rabbits. Controlled clinical trials continue to be the most scientifically valid method of evaluating standard treatments against the risks and benefits of medical innovations.

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Immune-related enzyme activities responded differently to MC-LR exposure. Some missense mutations changed essential residues conserved among Schizosaccharomyces species. The modifying effect of culture age on heat sensitivity of yeast. The mitochondrial ancestor of bonobos and the origin of their major haplogroups. Antibody- or DNA-based electrochemical systems have been developed widely for several decades, while carbohydrate-based electrochemical systems have been rarely reported. Innovative approaches to identifying and responding to the needs of high risk youth.

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Therapeutic approaches that consider environmental regulation could optimize chondrogenesis protocols for regeneration of articular cartilage. Neuromyelitis optica: importance of cerebrospinal fluid examination during relapse. Abnormal expression of chemokine receptors on T-cells from patients with systemic lupus erythematosus. The lysosomal permeability test modified for toxicity testing with cultured heart endothelioid cells. Data was analyzed with using Statistical Package for Social Sciences (SPSS) version 12 (Chicago, IL, USA). A quantitative morphological analysis including a comparison with infants of iso-immunized and of non-diabetic mothers. In contrast Cyp2a5, Cyp2b10 and Cyp2d9 expression were elevated. Assessing future changes in the occurrence of rainfall-induced landslides at a regional scale. SPECIMEN SAMPLE: Ten fresh-frozen human cadaveric cervical spine specimens were used, consisting of four females and six males, ranging in age from 32 to 68 years. Together, these data suggest the presence of an electrical feedback mechanism in the turtle retina, which therefore might be a common mechanism at the first visual synapse in vertebrates.

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To find out whether these abnormalities occurred only during dialysis sessions, 10 children with end-stage renal failure undergoing chronic dialysis were continuously monitored for 52 h during dialysis and between two sessions. superba results in gastrointestinal and haematological abnormalities, hepatic and renal insufficiency, cardiotoxicity and hair loss. Multiple dural arteriovenous fistulas presenting as rapidly progressive dementia. The need for this resolving power of the cell image analysis system is demonstrated by an example in the haematology. These findings suggest that analysis of the metabolic activities in peritoneal activated macrophages may provide a useful tool to dissect the central mediation of postsurgical peritoneal re-epithelialization. The fascial configuration in the suprahyoid parapharyngeal space was evaluated using semiserial sagittal sections of 15 late-stage human fetal heads. Non-Black married American women may face a risk of delivering low-birthweight babies at or near term only if they work 40 or more hours each week. In this paper we present an interesting case of acute kidney injury and severe metabolic alkalosis in a patient with a history of heavy heroin abuse.

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Animals were injected with a LD50 of micro-organisms and 4 hours later treated with a therapeutic i.m. Subsequent integration of drug-target data from drug databases with the predicted candidate genes can potentially identify novel therapeutics suitable for repositioning towards treatment of CAD. The presence of divalent cations and protein in the leukocyte suspension were found as well to be essential for cell migration. The mean serum level of HMGB1 protein of exposed group was higher than that one in the control group, however the difference was not statistically significant. We have determined the crystal structure of the AXH domain of ataxin-1.

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RNA Interference-Guided Targeting of Hepatitis C Virus Replication with Antisense Locked Nucleic Acid-Based Oligonucleotides Containing 8-oxo-dG Modifications. Interestingly, such a misfolding arises from non-native interactions involving the residues critical for the function of the protein. A regionwide intervention to promote appropriate antibiotic use in children reversed trends in erythromycin resistance to Streptococcus pyogenes. Water vapor transmission rate (WVTR) measuring devices with a quadrupole mass spectrometer (QMS) have an advantage in measuring low WVTRs because measurements are taken under an extremely low background of water vapor by realizing ultrahigh vacuum conditions. Chloramphenicol acetyltransferase (CAT) is the most commonly used reporter gene for studying the regulation of mammalian gene transcription. The maximum concentration of ACTH in the serum was dependent on the dose of histamine. Photographs of densely granulated cells, at various wavelengths of ultraviolet and visible light, indicated several different types of granules with respect to their absorption spectra. Main characteristics of his treatment are: Baside an approach saving the blood supply of bone, stable osteosynthesis, sequestrotomy and removal of necrotic tissues (focus elimination) filling in with autologous spongy bone chips the residual bone cavities, in acute stadium the application of PMMA balls as preparatory measure for a following cancellous bone, transplantation. Outbred guinea pigs became infected with the mite Trixacarus caviae (Acarina, Sarcoptidae) when introduced into an infected colony.

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Effect of exogenous insulin on fasting serum levels of gastric inhibitory polypeptide (GIP) in juvenile diabetes. Our findings provide novel molecular-scale strategies for designing functional gradient materials. Identification of New Candidate Genes and Chemicals Related to Esophageal Cancer Using a Hybrid Interaction Network of Chemicals and Proteins. Symposium on the problems of the warble fly and its eradication in the U.K. This review discusses the biologic roles of Plks in cell cycle progression and cancer, and the mechanisms of action of Plk inhibitors currently in development as cancer therapies. The aim of this study was to present our experience with this condition, by presenting an analysis of the clinical, diagnostic, and therapeutic data of our patients.

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Of the 27 botanicals screened, 10 exhibited a cytotoxic effect, 7 of which were ROS-mediated. FEAR AND PAIN: THEIR EFFECT ON SELF-INJECTION OF AMOBARBITAL SODIUM BY RATS. The antagonism of neuroleptics of various groups (chlorpromazine, chlorprothixene, clopenthixol, clozapine, flupenthixol, fluphenazine, haloperidol, levomepromazine, mepazine, perazine, perphenazine, pimozide, prochlorperazine, promazine, spiperone, thiopromazine, thioridazine, trifluperazine, trifluperidol, triflupromazine) towards L-5-hydroxytryptophan (5-HTP) was assessed on the basis of inhibition of characteristic head-twitches. Indications and applications in preprosthetic occlusional adjustments. In cases with peri- or intraarticular localisation symptoms suggestive of arthritis may occur. A total of 75 adults with major depressive disorder were randomized to receive weekly sessions of manualized individual CBT or IPT for a period of 16 weeks. The release of major and trace elements from recycled concrete aggregates used in an asphalt covered road sub-base has been monitored for more than 4 years. This qualitative study used semi-structured phone interviews with 32 instructors, staff members, and master trainers from 24 different YMCA-affiliated sites. A clinical series of patients was studied to compare the functional score after the use of a single versus two percutaneous iliosacral screws for unstable posterior pelvic ring fractures with or without anterior fixation with the aim to explore if the addition of a second screw would provide better results regarding the functional outcome score.

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This study revealed that hypothermically perfused livers, which mainly utilize endogenous fatty acids as an energy substrate during this time were adequately preserved for 72 h. Thus, the discrepancy between inferred population sizes from mtDNA and microsatellite data in tuna is most likely not an artifact of the chosen mutation models used in the microsatellite analyses, but may reflect behavioral differences between the sexes such as female-biased philopatry and male-biased dispersal. Temporal serum creatinine increase and exacerbation of tubulointerstitial inflammation during the first two months in resolving polyomavirus BK nephropathy. Disorders of the drainage function of the bronchi reflected mostly the character of the specific lesion of the pulmonary tissue and was most pronounced in patients with fibrous-cavernous cirrhotic tuberculosis. Computer applications at the University of Alabama Medical Center. The methods capable of in vivo application are extremely limited. We show in an adipose cell line that IDV and NFV induced alterations at the nuclear level by promoting defects in lamin A/C maturation, organization and stability. Signal transducer and activator of transcription (STAT) 6 signaling pathway is required for mediating the biologic functions of interleukin (IL)-4 which is proved to play an important role in the pathogenesis of allergic diseases and the induction of specific immunoglobulin (Ig) E synthesis.

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Our review shows that bisphosphonates reduce vertebral fractures in short term use while in long-term can cause osteonecrosis jaw, esophageal cancer, atrial fibrillation, and increase the risk of atypical fractures and probably adynamic bone disease. DEHP was found in the highest concentration in almost every group. The condition had previously responded to moderate dose oral prednisolone, 50 mg daily, but would recur with weaning. The value of polyglobulism as a mechanism of compensation in congenital cardiac defects. The amount of virus present at the downstream stages in the process is expected to be and is typically low.

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attachment to peritoneal or alveolar macrophages was not markedly affected by galactose-derivative molecules. Previous studies have shown that preliminary standardized assessment tools can be reliably administered and scored via VC. In both C-6 glial cells and NB cells, unincorporated 3H-leucine decreased, whereas incorporation of 3H-leucine into protein increased with increasing cell density, particularly at high cell densities. I1-2R was increased in all patients compared to normal subjects, without any intradialytic change, regardless of the type of membrane used. EVALUATION OF ARTERIOGRAPHIC DATA IN OPEN FRACTURES OF THE BONES OF THE EXTREMITIES.

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Chlamydia trachomatis serovars and the clinical picture of urogenital infections. Mortality of the Asian corn borer (Ostrinia furnacalis) was used for assessing efficacy of culture filtrates and how much does ventolin cost in usa conidial suspensions of transgenic Trichoderma strains against the insect. Furthermore, most of the patients (14/15) were receiving diuretics. Coat color and biochemical variation in Amazonian wild populations of Alouatta belzebul. Basic studies on the resistance of tubercle bacilli to alpha-ethyl-thioisonicotinamide (1314th). Effect of cimetidine on lactose activity in patients with duodenal ulcer. Anastomosis of serosaless and serosa-containing intestinal incisions (sleeve anastomosis.

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A hyperdense lesion was visible in the right thalamic region on the cerebral CT scan. Factors that increased the probability of shorter survival included greater age at diagnosis, male gender, lower KPS, not having total resection, and unmethylated MGMT status. However, survival of the DeltanrdZ mutant strain was not impaired under hypoxic conditions in vitro. Cardiac tissue from patients with DCM and, for control purposes, cardiac tissue from patients with other forms of cardiomyopathy and from patients with no history of cardiac disease were stained with heterologous and ANT-, BCKD-, and myosin-specific affinity-purified sera from DCM patients. At least some biospheric phenomena fitted concomitantly with 1- and 0.5-year cosine curves exhibit an amplitude (A) ratio of A(0.5-year)/A(1-year) larger than unity. Phage lytic enzyme Cpl-1 as a novel antimicrobial for pneumococcal bacteremia. Chlamydia pneumoniae accelerates coronary artery disease progression in transgenic hyperlipidemia-genetic hypertension rat model. Endothelial permeability increase produced by angiographic contrast media. The sensitivity and reduction of number needed to colonoscope (NNScope) of each screening strategy were assessed. Risk factors for bovine Tuberculosis at the national level in Great Britain.

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Microglial cells in the central nervous system of the rabbit and rat: cytochemical identification using two different lectins. Telomeres are typically shorter in men than in women and continue to shorten over the life-span. Various binding characteristics of 6- xanax medication class shogaol-HSA interaction were studied using fluorescence spectroscopy. Global Prevalence of Helicobacter pylori Infection: Systematic Review and Meta-Analysis. The present study was designed to determine whether common neuroadaptations underlie the acute and sensitized responses to MDMA and AMPH. Effects of entecavir and Shenxian Yiganling combination therapy on patients with HBeAg-positive chronic hepatitis B for 48 weeks. After the treatment of more than 10(9-) mol/L Psi-RACK (PKC-epsilon activator), the contractility of myometrium strips from mice was reinforced and the level of phosphorylated h1 calponin increased at the same time which could be interrupted by the specific inhibitor of PKC-epsilon. In Memoriam: Jean Lindenmann (1924-2015): A Circuitous Interfering Power in Neurology. Benefits of mammography in women aged 50-69 outweigh risks, says expert panel.

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These Malay sub-ethnic groups show closer genetic relationships with other Asian populations than with Europeans and Africans. Daily emergency room admissions for chronic obstructive pulmonary disease increased by 0.02 and 0.01 for each microgram of sulfur dioxide and black smoke per cubic meter, respectively, and 0.11 for each milligram of carbon monoxide per cubic meter, after adjusting for meteorologic and temporal variables. The steady-state analytical solutions are shown to be accurate and the numerical program RT3D is selected for comparison. The ratio of PEI to DNA was most important for the formation of small polyplexes, whereas other parameters had minor influence. Mollisin exhibited a molecular mass of 28 kDa in sodium dodecyl sulfate-polyacrylamide gel electrophoresis as well as in gel filtration on Superdex 75 by fast protein liquid chromatography. The Physical Mobility Scale items, two upper limb function measures, range limitation of hip and knee extension and gleno-humeral movement were assessed.

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Concomitant omphalocele, anencephaly and arthrogryposis associated with trisomy 18. The study of evolution provides invaluable insights into human structure and function. Hepatitis B virus (HBV) reactivation can occur in persons who are hepatitis B surface antigen (HBsAg)-negative but hepatitis B core antibody (anti-HBc) positive, especially bacterial vaginosis flagyl dosage following hematopoietic stem cell transplantation (HSCT). The cost-effectiveness ratio of bupropion at 5 years was 70,939 euros per death prevented and was 37,305 euros per year of life saved. Matrix-assisted laser desorption/ionization-time of flight mass spectrometry was used to identify isolates to genus level, followed by recA/gyrB sequence clustering or species-specific PCR. Whilst these deficits can be localised predominantly to frontal and parietal regions, there have been reported inconsistencies which may be due to differences in the difficulty and type of task. Law matters: How the legal context in Canada influences interprofessional collaboration. There was a striking trend for a protective effect of multiparity in both countries and a weak but inconstant protective effect of age at first birth. Biochemical evidence of cocarcinogenesis: tumor promoting agent enhances methylnitrosourea activation of rat guanylate cyclase activity.

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Nitric oxide induces hypoxia-inducible factor 1 activation that is dependent on MAPK and phosphatidylinositol 3-kinase signaling. Since these parameters are objective, they are not affected by patient histories and hence, can be utilized to track the ongoing EEG activity and the accompanying clinical state regardless of the disease entity or the course of therapy pursued. We analyzed the nutritional status according to BMI for age in relation to the NCHS references and WHO 2007, in standard deviations (SD) and percentiles. The analysis permits precise statements to be made about the minimum set of distances that specify a unique structure without recourse to energy minimization. The MitoRS method enables the robust, accurate, and sensitive analysis of a large number of samples. Is complementary and alternative therapy effective for women in the climacteric period?. The review deals with quantitative laws of monochromatic visible light action on the cellular level, as well as with the primary photoacceptors and possible light signal transduction chains in bacterial cell Escherichia coli WP2 trp-. sajanense as what is the drug vermox used to treat a distinct lineage that is weakly supported as sister to E. Long-term care should occur in a specialized limb deficiency center with expertise in orthopedics, prosthetics, and occupational and physical therapy and provide emotional support and contact with other families.

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Multiple sclerosis (MS) is a chronic neurological condition, characterized by recurrent episodes of inflammation and demyelination of the central nervous system called relapsing-remitting episodes, and continuous axonal degeneration that leads to irreversible progressive invalidity. There were also patients on symptomatic treatment aimed at reduction of body weight. Further work is needed to understand the pathophysiologic mechanisms involved, and to identify the safest ARV regimens to be used in pregnancy. Simulation of osteotomies for advancement plasty and craniofacial reassembly in the model before surgery in group I reduced operating time and intraoperative errors. The question of whether people who stutter are generally more anxious than people who do not stutter has not yet been resolved. We investigated a model of a lethal graft-versus-host (GVH) reaction with the aim of depleting donor spleen cells of immunospecific GVH-reactive lymphocytes. The purpose of this study was to evaluate placental lesions found in women with norethindrone acetate and ethinyl estradiol dose preeclampsia compared with normotensive control subjects and to determine whether the presence of these lesions are related to gestational age at delivery. ENOVID: CONTRACEPTIVE PILL AND RECENT FDA REPORT CLEARING IT STIR CONTINUED MEDICAL DISPUTE.

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The dangers and disadvantages of barbiturates are described and the value and limitations of other drugs are considered. Studies of blood lead levels in children by proton-induced X-ray emission (PIXE). A quantitative assay of covalently bound cephalosporin derivatives in cephalosporin-protein conjugates. To better understand the immunity induced in this tumor model, immunization using freeze-thaw DMBA-4 cell lysates was performed, followed by tumor challenge 21 days later. The program affected family physicians because immunization strategies designed for immunizing high-risk patients needed to be modified to deal with greater numbers of patients. (1991) sought to improve the well-being of elderly women by providing friendly telephone contact with staff or peers. In this cross-sectional study during 2006 to 2013, data were collected from medical records of brain dead patients. Energy expenditure and substrate use were measured for 24 h in a respiration chamber. Convulsive manifestations in children and the function of adrenal cortex.

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When compared with a control group, falls in systolic and diastolic blood pressure and tachycardia following intravenous PGI2 were significantly reduced in those animals exposed to smoke 1 and 24 h previously. High degree of conversion of angiotensin I to angiotensin II in the mesenteric circulation of the isolated perfused terminal ileum of the cat. The differences of the resistance rates were more prominent for oral second-line drugs. A self-report measure of pretreatment depressive symptoms was completed by 141 participants from the Providence Clinical Research Unit of Project MATCH. Adapted to flee famine: adding an evolutionary perspective on anorexia nervosa. To develop a new green approach for biosynthesis of silver nanoparticles, myconanotechnology has been represented as a novel field of study in nanotechnology. A review of necrotising external otitis, a relatively unknown and dangerous disease, brings out that, initially, it has three characteristics: a granulating necrotising ostitis of the external meatus, extreme pain and a yellowish green secretion. Enterokinase treatment resulted in complete proteolysis of VacA into p-33 and p-55 domains, which remained physically associated within oligomeric structures and retained vacuolating cytotoxin activity.

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