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Bionoliprel (Aceclofenac)
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Bionoliprel

Bionoliprel is a medication used to treat high blood pressure, heart failure, or stable coronary artery disease. As a long-acting ACE inhibitor, it works by relaxing blood vessels and decreasing blood volume. As a prodrug, perindopril is hydrolyzed to its active metabolite, perindoprilat, in the liver.

Other names for this medication:
Aceclofenac, Acertil, Agulan, Aldoc, Asyntilsan, Bionoliprel, Biprel, Cardipen, Coverene, Coverex, Covinace, Dorover, Indapril, Midopril, Noliprel, Pendoril, Pendrex, Percarnil, Perindal, Perindan, Perindo, Perindox, Prestarium, Prexanil, Prexum, Procaptan, Provinace, Reaptan, Stopress, Teraxans, Vectoryl, Vidotin

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Also known as: Aceclofenac

Description

Bionoliprel is an angiotensin-converting enzyme (ACE) inhibitor. It works by blocking ACE, an enzyme involved in narrowing blood vessels and causing sodium and fluid retention by the kidneys. This causes blood vessels to relax, allowing blood to flow more freely and at a lower pressure, and increasing the heart's ability to pump blood in some types of heart failure. Bionoliprel is also known as Coversyl, Perindopril, Acertil, Armix, Coverene, Coverex, Coversum, Prestarium, Prexanil, Prexum, Procaptan. Generic name of Bionoliprel is Perindopril. Brand name of Bionoliprel is Bionoliprel.

Dosage

Usual Adult Dose for Coronary Artery Disease:

Initial dose: 4 mg orally once a day for 2 weeks, then increase to maintenance dose as tolerated. Maintenance dose: 8 mg orally once a day Use: Treatment of patients with stable coronary artery disease to reduce the risk of cardiovascular mortality or nonfatal myocardial infarction.

Usual Adult Dose for Hypertension:

Initial dose: 4 mg orally once a day Maintenance dose: 4 to 8 mg orally per day in 1 or 2 divided doses Maximum dose: 16 mg/day Comments: In patients treated with a diuretic, consider reducing the diuretic dose prior to starting this drug.

Usual Geriatric Dose for Coronary Artery Disease:

Greater than 70 Years: Initial dose: -Week 1: 2 mg orally once a day -Week 2: 4 mg orally once a day, then increase to maintenance dose as tolerated. Maintenance dose: 8 mg orally once a day Use: Treatment of patients with stable coronary artery disease to reduce the risk of cardiovascular mortality or nonfatal myocardial infarction.

Usual Geriatric Dose for Hypertension:

Initial dose: 4 mg orally per day in 1 or 2 divided doses Comments: Experience with doses above 8 mg is limited; administer with careful blood pressure monitoring and dose titration.

Detailed Bionoliprel dosage information

Overdose

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Storage

Store at room temperature between 20 and 25 degrees C (68 and 77 degrees F) away from moisture and heat. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Bionoliprel are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Do not take Bionoliprel if you are allergic to Bionoliprel components. Be careful with Bionoliprel if you're pregnant or you plan to have a baby, or you are a nursing mother. Do not use potassium supplements or salt substitutes. If you want to achieve most effective results without any side effects it is better to avoid alcohol. Be very careful when you are driving machine. Bionoliprel may lower your resistance to infection. Prevent infection by avoiding contact with people with colds or other infections. Do not touch you eyes or the inside of your nose unless you have thoroughly washed your hands first. Do not stop taking Bionoliprel suddenly.

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