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Biseptol (Trimethoprim)

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This medication is a combination of two antibiotics: sulfamethoxazole and trimethoprim. It is used to treat a wide variety of bacterial infections (such as middle ear, urine, respiratory, and intestinal infections). It is also used to prevent and treat a certain type of pneumonia (pneumocystis-type). This medication treats only certain types of infections. It will not work for viral infections (such as flu). Unnecessary use or misuse of any antibiotic can lead to its decreased effectiveness.

Other names for this medication:
Anitrim, Bacterol, Bactramin, Bactricida, Bactropin, Bascul, Berlocid, Bioprim, Cadiprim, Cotribene, Cotripharm, Cozole, Ditrim, Dosulfin, Droxol, Esbesul, Kemoprim, Kombitrim, Lagatrim, Letus, Licoprima, Linaris, Neotrim, Nufaprim, Omsat, Plocanmad, Politrim, Primotren, Sigaprim, Sinersul, Spectrem, Sulbron, Sulfametoxazol, Sulfoid, Sulmetrim, Sultrim, Sumetrolim, Suprimass, Sutrim, Terbosulfa, Theraprim, Trelibec, Trimecor, Urisept

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Also known as: Trimethoprim


Sulfamethoxazole and trimethoprim combination is used to treat infections such as urinary tract infections, middle ear infections (otitis media), bronchitis, traveler's diarrhea, and shigellosis (bacillary dysentery). This medicine is also used to prevent or treat Pneumocystis jiroveci pneumonia or Pneumocystis carinii pneumonia (PCP), a very serious kind of pneumonia. This type of pneumonia occurs more commonly in patients whose immune systems are not working normally, such as cancer patients, transplant patients, and patients with acquired immune deficiency syndrome (AIDS).

Sulfamethoxazole and trimethoprim combination is an antibiotic. It works by eliminating the bacteria that cause many kinds of infections. This medicine will not work for colds, flu, or other virus infections.

This medicine is available only with your doctor's prescription.


Take this medication by mouth, as directed by your doctor, with a full glass of water (8 ounces / 240 milliliters). If stomach upset occurs, take with food or milk. Drink plenty of fluids while taking this medication to lower the unlikely risk of kidney stones forming, unless your doctor advises you otherwise. Dosage is based on your medical condition and response to treatment. Antibiotics work best when the amount of medicine in your body is kept at a constant level. Therefore, take this drug at evenly spaced intervals. Continue to take this medication until the full prescribed amount is finished, even if symptoms disappear after a few days. Stopping it too early may allow bacteria to continue to grow, which may result in a relapse of the infection. Tell your doctor if your condition persists or worsens.


If overdose is suspected, contact a poison control center or emergency room immediately. US residents can call their local poison control center at 1-800-222-1222. Canada residents can call a provincial poison control center. Symptoms of overdose may include: severe nausea/vomiting/diarrhea, severe dizziness or drowsiness, mental/mood changes.


Store at room temperature away from light and moisture. Do not store in the bathroom. Keep all medications away from children and pets. Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company.

Side effects

The most common side effects associated with Biseptol are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Before using sulfamethoxazole with trimethoprim, tell your doctor or pharmacist if you are allergic to sulfa medications or trimethoprim; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details. Before using this medication, tell your doctor or pharmacist your medical history, especially of: kidney disease, liver disease, certain blood disorders (such as porphyria, anemia due to folate vitamin deficiency), history of blood disorders caused by trimethoprim or sulfa medications, vitamin deficiency (folate or folic acid), severe allergies, asthma, decreased bone marrow function (bone marrow suppression), a certain metabolic disorder (G6PD deficiency), underactive thyroid, mineral imbalances (such as high level of potassium or low level of sodium in the blood). Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products). This medication may make you more sensitive to the sun. Avoid prolonged sun exposure, tanning booths or sunlamps. Use a sunscreen and wear protective clothing when outdoors. If you have diabetes, this product may affect your blood sugar levels. Check your blood sugar levels regularly as directed by your doctor. Tell your doctor immediately if you have symptoms of low blood sugar (see Side Effects section). Your doctor may need to adjust your diabetes medication, exercise program, or diet. Older adults may be more sensitive to the side effects of this drug, especially skin reactions, blood disorders, easy bleeding/bruising, and a high potassium blood level. Patients with AIDS may be more sensitive to the side effects of this drug, especially skin reactions, fever, and blood disorders. This medication is not recommended for use during pregnancy especially near the expected delivery date because of possible harm to the unborn baby. Consult your doctor for more details. This drug passes into breast milk. While there have been no reports of harm to healthy infants, this drug may have undesirable effects on infants who are ill or premature or have certain disorders (jaundice, high blood levels of bilirubin, G6PD deficiency). Therefore, breast-feeding is not recommended for infants with these conditions. Consult your doctor before breast-feeding.

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7 cases of heterotopic pancreatic islands simulating gastroduodenal ulcer. 154 patients were diagnosed with coronary artery disease, and 156 with non-coronary artery disease, which was confirmed with diagnostic coronary angiography. Food Quality Monitor: Paper-Based Plasmonic Sensors Prepared Through Reversal Nanoimprinting for Rapid Detection of Biogenic Amine Odorants. When the IPPB machines were driven by compressed air instead of oxygen, this complication was revealed in 1 of the patients. Conversely, morbidity may be decreased by prescriptions associated with more efficient removal of urea if the dietary intake of protein and other nutrients is adequate. Carminomycin eliminated the RTAH only when it was administered to the recipients of the allogenic lymphoid cells 24 hours after implantation of the cells to the mice treated with cyclophosphamide. Structurally, eukaryotic FEX proteins consist of two homologous four-transmembrane helix domains folded into an antiparallel dimer, where the orientation of the two domains is fixed by a single transmembrane linker helix. Cross-Phosphorylation and Interaction between Src/FAK and MAPKAP5/PRAK in Early Focal Adhesions Controls Cell Motility.

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Combination cyclophosphamide, doxorubicin, and cisplatin (CAP) chemotherapy for extensive non-small cell carcinomas of the lung. This summary presents the questions identified by the meeting participants and their relative priority within the following categories: (1) measles epidemiology, (2) vaccine development and alternative vaccine delivery, (3) surveillance and laboratory methods, (4) immunization strategies, (5) mathematical modeling and economic analyses, and (6) rubella/CRS control and elimination. There was no evidence that forward collision warning and other technologies like those in this study will increase or decrease distracted driving. Cerebrovascular injury has not been previously associated with endomyocardial biopsy. In cultivation of meningococcus of serological group A in fluid semisynthetic medium of simple composition prepared on the basis of purified acid casein hydrolysate with profound splitting there were obtained microbial cultures with a density of 4-5 x 10(9) microbial cells per 1 ml after 20-24 hours of cultivation with shaking. Real-time detection of hypochlorite in tap water and biological samples by a colorimetric, ratiometric and near-infrared fluorescent turn-on probe. CONTRIBUTION TO THE TOXIC EFFECTS OF ADRENALIN AND ITS METABOLITES. Lungworm (Dictyocaulus sp.) is the parasite of most concern to the New Zealand deer industry. Effect of pH on the response of adrenal medulla to various agonists.

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Forty CHB patients were enrolled to quantify the hepatic phospho-STAT3 (p-STAT3) levels and correlated with liver fibrosis. Cyclic mechanical stretch-induced oxidative stress occurs via a NOX-dependent mechanism in type II alveolar epithelial cells. Evidence for a neuronal release of isotopically labelled gamma-amino-n-butyric acid (GABA) from the rat dorsal medulla in vivo. These atmospheric pollutants have been incriminated in deleterious health effects by numerous epidemiological and in vitro studies. Further advances in interpretation are likely with more frequent use of bone marrow trephines.

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This might explain, partially, the high dental treatment needs of the Israeli military population. subterraneus is related to a specific patterns of genetic variation, including inbreeding estimates. Rearrangements of ribosomal DNA clusters in late generation telomerase-deficient Arabidopsis. Generation of a temperature-sensitive Edwardsiella tarda mutant and its potential as a prophylactic vaccine in olive flounder (Paralichthys olivaceus). Mesenchymal stem cells (MSCs) are widely recognized as critical players in tissue regeneration. Current studies fail to give more than sparse evidence to support the use of interventional techniques in the treatment of lumbar zygapophysial joint-mediated low back pain. Infectious and inflammatory diseases are important causes of infertility, and recent evidence points to the critical role of the early-life microbial environment in developmental programming of adult reproductive fitness. We also highlight the most important ongoing clinical and translational research questions that hope to help better predict and prevent this toxicity. NPs in the PIT role ordered slightly less diagnostic tests than attending physicians. High attenuation and immunogenicity of a simian immunodeficiency virus expressing a proteolysis-resistant inhibitor is it safe to take ambien with alcohol of NF-kappaB.

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Most of the studies have serious problems of lack of power because of small sample size, bias and confounding variables, lack of method error analysis, blinding in measurements, and deficient or lack of statistical methods. On the one hand, miRNA expression may be regulated by epigenetic mechanisms including DNA methylation and histone modifications. The thermal inactivation of these enzymatic activities of alpha subunit from the wild-type virus. Quality improvement and psychiatric research: can design thinking bridge the gap?. Association between serum phospholipid fatty acid levels and adiposity in Mexican women. The levels of AEA in the gingival crevicular fluid (GCF) of periodontitis patients were measured using liquid chromatography/mass spectrometry (LC/MS). Gamma radiation inhibited hatching rate and caused developmental impairment in a dose-dependent manner.

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Serum cholesterol, triglyceride and uric acid levels as well as urinary 17-hydroxycorticosteroid excretion in cases of recent myocardial infarction. The Tritocerebrum is very reduced and has in its anterior part two very short frontal connectives and, by this, the frontal ganglion lies near the Tritocerebrum. This paper uses longitudinal survey data linked to generic xanax pill pictures administrative registers to examine socioeconomic gradients in health, particularly whether the effects of genetic endowments interact with the socioeconomic resources of the parental household. The medial retropharyngeal lymph nodes may be the most relevant draining lymph node of the head and neck, but they are not routinely sampled due to their anatomic location medial to the salivary glands. ROLE OF THE ADRENAL CORTEX IN THE METABOLISM AND ELECTROGENESIS OF THE CENTRAL NERVOUS SYSTEM. The highest stimulation was found in the testis of 2-day-old rats after-which cAMP synthesis diminished with advancing age.

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