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Bludol (Tramadol)

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Bludol is used for the management of pain in adults. Although it's a little weaker than other opioids, it can still be addictive and habit-forming. Bludol is available as both an immediate-acting tablet and an extended-release tablet.

Other names for this medication:
Acupain, Acuvin, Adamon, Arrestadol, Bramadol, Cadol, Contramal, Cormadol, Dolex, Dolomed, Dolriz, Drobit, Ivydol, Mandol, Medol, Midol, Nictram, Painex, Rimol, Rybix, Simol, Spasteez, Tamody, Tragesic, Traiz, Tramasol, Tramatas, Tramed, Trampar, Tromfil, Trugesic, Ultrazac, Unidol, Vegadol, Vintram

Similar Products:
Detrol, Loxitane, Colospa, Arimidex, Vantin, Colcrys

Also known as: Tramadol


{name} ER is an pain medicine similar to an opioid. This medicine is used to treat moderate to severe pain.

The extended-release form of tramadol is for around-the-clock treatment of pain. This form of tramadol is not for use on an as-needed basis for pain.


Usual Adult Dose for Pain:

Adults (17 years or older): 50 to 100 mg orally every 4 to 6 hours as needed for pain -For patients not requiring rapid onset of analgesic effect: Initial dose: 25 mg orally once a day; titrate in 25 mg increments every 3 days to reach a dose of 25 mg four times a day; thereafter increase by 50 mg as tolerated every 3 days Maximum dose: 400 mg per day.

Usual Adult Dose for Chronic Pain:

Extended-Release (ER): 18 years or older (tramadol-naive): 100 mg orally once a day -Individually titrate in 100 mg increments every 5 days to an effective dose that minimizes adverse reactions -Maximum Dose: 300 mg/day For patients CURRENTLY receiving Immediate-Release (IR) Bludol: Initial Dose: Calculate 24-hour IR requirement and initiate with a total daily ER dose rounded down to the next lowest 100 mg increment orally once a day Conversion from OTHER Opioids: Discontinue all other around the clock opioid drugs prior to initiating therapy -Initial dose: 100 mg ER orally once a day -Individually titrate in 100 mg increments every 5 days to an effective dose that minimizes adverse reactions -Maximum Dose: 300 mg/day.

Usual Geriatric Dose for Pain:

Dose selection should be cautious generally starting at the low end of the dose range Over 75 years: Maximum dose of Immediate-release: 300 mg per day.

Usual Geriatric Dose for Chronic Pain:

Dose selection should be cautious generally starting at the low end of the dose range Over 75 years: Maximum dose of Immediate-release: 300 mg per day.

Usual Pediatric Dose for Pain:

Bludol is not recommended for use in pediatric patients 17 years or older: See Adult Dose.

Detailed Bludol dosage information


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose can be fatal, especially in a child or other person using the medicine without a prescription. Overdose symptoms may include severe drowsiness, pinpoint pupils, slow breathing, or no breathing.

Your doctor may recommend you get naloxone (a medicine to reverse an opioid overdose) and keep it with you at all times. A person caring for you can give the naloxone if you stop breathing or don't wake up. Your caregiver must still get emergency medical help and may need to perform CPR (cardiopulmonary resuscitation) on you while waiting for help to arrive.

Anyone can buy naloxone from a pharmacy or local health department. Make sure any person caring for you knows where you keep naloxone and how to use it.


Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) away from moisture and heat. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Bludol are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Do not drink alcohol. Dangerous side effects or death could occur.

Avoid driving or hazardous activity until you know how Bludol ER will affect you. Dizziness or drowsiness can cause falls, accidents, or severe injuries.

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Comparison of text-messaging to voice telephone interviews for active surveillance of adverse events following immunisation. Results showed that these STLs inhibited cell proliferation in a concentration-dependent manner by exerting cytotoxicity through apoptosis. Changes in high-sensitivity C-reactive protein in serum and exhaled breath condensate after intensive exercise in patients with allergic asthma. Women bound to be active (years 3 and 4): can a book club help women overcome barriers to physical activity and improve self-worth?. A prosegment of the yeast alpha-factor controls a heterologous protein (human growth factor) in Saccharomyces cerevisiae culture media. Influence of Color-to-Gray Conversion on the Performance of Document Image Binarization: Toward a Novel Optimization Problem. NE shifted the venous return curve (i.e., increased MCFP) to the right without changing RVR, and increased cardiac output (CO) both at baseline and after endotoxin. Treatment costs of directly observed therapy and traditional therapy for Mycobacterium tuberculosis: a comparative analysis. This behavior can be qualitatively reproduced, using a stochastic classical field model describing interaction between the polariton condensate and the exciton reservoir within a disordered potential.

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Daily psychosocial stressors interfere with the dynamics of urine neopterin in a patient with systemic lupus erythematosus: an integrative single-case study. Changes in receptors and nerves in skin with and without pathological changes in progressive atrophy and scleroderma. Physicians in primary care rank hospital recommendations as one of the most important sources of information on new drugs. The F231L mutation results in only a small disturbance of the ERCC1-XPF interface, where, in contrast to Phe(231), Leu(231) lacks interactions stabilizing the ERCC1-XPF complex. Ionic liquids reduce the materials and energy intensity of chemical processes and products, minimize or eliminate the dispersion of harmful chemicals in the environment, maximize the use of renewable resources and extend the durability and recyclability of products. In conclusion, regions encoded by the first exon of tat are necessary and sufficient for activation of VEGFR-2. High Diagnostic Yield of Dedicated Pulmonary Screening before Hematopoietic Cell Transplantation in Children. The authors computed prevalence estimates (weighted percentages), weighted means and standard errors for measures.

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A study of the biomechanical properties of the adult equine linea alba: relationship of tissue bite size and suture material to breaking strength. Measurement of global and separate renal blood flow using cine-computed tomography. Primary goat synovial membrane (GSM) cells are widely used to study small ruminant lentiviruses (SRLV), i.e. The objectives of this study are to provide data regarding the prevalence of anti-cyclic citrullinated peptide (CCP) antibodies in Malaysian rheumatoid arthritis (RA) patients and to correlate the zantac generic price levels of anti-CCP antibody with the Disease Activity Score (DAS). The apparent inhibition constant for hexylresorcinol and dodecylresorcinol binding with free enzyme has been determined to be 0.443 and 0.405 microM for diphenolase, respectively.

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Natural killer (NK) cells are crucial to mounting an effective immune response. Vessel characteristics were not significantly different between TIA and infarction patients. On the function of the intrinsic laryngeal muscles and the recurrent nerve. FCgammaRII (CD32)-dependent induction of interferon-alpha by serum from patients with lupus erythematosus. We found that the most active antibiotics on intracerebral bacteria were amoxycillin, co-trimoxazole, rifampicin and imipenem.

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Effect of fluorescent radiations of calcium tungstate on experimental peritoneal tuberculosis. The available evidence indicates that the coordination of multiple signaling networks, rather than individual separate pathways, links the mechanical signals to specific genetic circuitries in orchestrating the mechanoresponsive networks to evoke comprehensive genetic and functional responses. It is common to find specially constructed condition-specific health state descriptions used as the basis for benefit assessment in cost-utility analysis. To compare diagnostic performance of color Doppler ultrasound and CA- the medication lioresal 125 in suspicious adnexal masses on B-mode sonography. MoDPepInt: an interactive web server for prediction of modular domain-peptide interactions. Genetic pleiotropy, the phenomenon by which mutations in the same gene result in markedly different disease phenotypes, has proven difficult to explain with traditional models of disease pathogenesis. Partitioning of the relevance network revealed seven distinct communities comprising functionally related genes associated with host inflammatory and immune responses.

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Reproductive development of controls held for 4.5 months on constant short days (5L:19D) was negligible in redpolls and crossbills, but substantial in siskins, suggesting that of the three species, pine siskins may be the least dependent on long days for reproductive development. In children undergoing chest radiography what is the specificity of rib fractures for non-accidental injury?. A theoretical relationship is developed between the virial cross coefficient and the chromatographic retention using statistical mechanics. Treatment services provided or brokered by the community mental health center staff include psychiatric and medical treatment, intensive case management, addictions treatment, urine toxicology screening, psychosocial or residential rehabilitation services, intensive outpatient care, partial hospitalization, and inpatient treatment. The AMTL field potential at 400 msec shares characteristics with the N400 potential recorded from scalp electrodes that has been associated with semantic processing.

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Pharmacokinetics and pharmacodynamics of a slow-release formulation of diltiazem after the administration of a single and repeated doses to healthy volunteers. Morphology of the hypothalamus of the white rat (karyometric observations). Co-culture of motor neurons on astrocyte monolayers delayed, but did not prevent, nitrotyrosine-induced motor neuron death. The VV signal at the arterial adventitia of the common carotid artery was evaluated by contrast-enhanced ultrasound imaging. The conformations found in H2O and in DMSO-d6 solutions are valuable for the design of peptidomimetics of these two pharmacophores. The KA questionnaire, adapted for Turkish population, was distributed among patients after establishing whether they received diabetes education. A new recipient artery for reconstruction of soft-tissue defects in the lower limb with a free anterolateral thigh flap: the reversed descending branch of the lateral femoral circumflex artery. Primary or secondary prevention treatment prior to admission was assessed using a data collection tool of 16 criteria developed from the Scottish Intercollegiate Guidelines Network (SIGN) guidelines. A method for the restoration of complete continence after colectomy in polyposis of the colon and rectum.

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Lactic acid treatment of TWC01 resulted in downregulation of channel protein and adherence-related protein expressions. Concurrent group and individual psychotherapy in a psychiatric day hospital for depressed elderly. The impact of early adverse experiences on brain systems involved in the pathophysiology of anxiety and affective disorders. The final outcome on vectorial capacity depended on the specific combination of MF, virus, and mosquito species involved. Unit-cell dimensions and space group of 6-mercaptopurine monohydrate. Implications for management of complex congenital tenormin 50 mg tablet heart disease. Lastly, the available data concerning the electron exchange between cytochromes c3 and their redox partners can be analysed through a detailed kinetic model which provides important information on the role of the different hemes. Expression of beta1A or the cytoplasmic splice variant beta1D, induced the disruption of intercellular adherens junctions and cell scattering in both GE11 and GD25 cells. The inflammatory profile of villous tissue was studied in pregnancies at high-risk of placental dysfunction and compared to uncomplicated pregnancies.

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OS favored the bevacizumab plus IFN-alpha arm but did not meet the predefined criteria for significance. Cell cholesterol efflux to reconstituted high-density lipoproteins containing the apolipoprotein A-IMilano dimer. Volume-dependent collection of peripheral blood progenitor cells during large-volume leukapheresis for patients with solid tumours and haematological malignancies. Communication skills training for health care professionals working with cancer patients, their families and/or carers. Malaria Prevalence among Young Infants in Different Transmission Settings, Africa. The grafting ratio of PMMA increased as the weight ratio between MMA and nano-CaCO(3) increased, while the grafting efficiency of PMMA decreased. Our data show that NPY expression is increased during atherogenesis and in particular in unstable plaques. The variations in aromatic character are insightful and provide a deeper understanding of aromaticity and conjugation in porphyrinoid structures.

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