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Bupropion is an antidepressant medication that works in the brain. It is approved for the treatment of major depressive disorder (MDD), seasonal affective disorder (SAD), and to help people quit smoking (smoking cessation). Symptoms of depression include: Depressed mood - feeling sad, empty, or tearful.

Other names for this medication:
Aplenzin, Budeprion, Bupdep, Bupraset, Bupron, Bupropion, Ession, Nicotex, Smoquit, Unidep, Zyban

Similar Products:
Intagra, Addyi, Lunesta, Eulexin, Duphaston, Xenical


{name} (bupropion) is an antidepressant medication used to treat major depressive disorder and seasonal affective disorder.


Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose. Use the medicine exactly as directed. Too much of this medicine can increase your risk of a seizure.

You may take Bupropion SR with or without food.

Swallow the extended-release tablet whole and do not crush, chew, or break it.

You should not change your dose or stop using Bupropion SR suddenly, unless you have a seizure while taking this medicine. Stopping suddenly can cause unpleasant withdrawal symptoms. Ask your doctor how to safely stop using this medicine.

If you take Zyban to help you stop smoking, you may continue to smoke for about 1 week after you start the medicine. Set a date to quit smoking during the first 2 weeks of treatment. Talk to your doctor if you have trouble quitting after taking Zyban for 7 to 12 weeks.

Your doctor may prescribe a nicotine replacement product (such as patches or gum) to help you stop smoking. Start using the nicotine replacement product on the same day you stop (quit) smoking or using tobacco products.

Some people taking Bupropion SR (Bupropion or Zyban) have had high blood pressure that is severe, especially when also using a nicotine replacement product (patch or gum). Your blood pressure may need to be checked before and during treatment with this medicine.

Read and carefully follow any Instructions for Use provided with your medicine. Ask your doctor or pharmacist if you do not understand these instructions.

You may have nicotine withdrawal symptoms when you stop smoking, including: increased appetite, weight gain, trouble sleeping, trouble concentrating, slower heart rate, having the urge to smoke, and feeling anxious, restless, depressed, angry, frustrated, or irritated. These symptoms may occur with or without using medication such as Zyban.

Smoking cessation may also cause new or worsening mental health problems, such as depression.

This medicine may affect a drug-screening urine test and you may have false results. Tell the laboratory staff that you use Bupropion SR.

Store at room temperature away from moisture, heat, and light.

Detailed Bupropion SR dosage information


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose of Bupropion SR can be fatal. Overdose symptoms may include muscle stiffness, hallucinations, fast or uneven heartbeat, shallow breathing, or fainting.


Store at room temperature between 20 and 25 degrees C (68 and 77 degrees F) away from moisture and heat. Keep container tightly closed. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Bupropion are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


You should not take Bupropion SR if you are allergic to it, or if you have:

a seizure disorder; an eating disorder such as anorexia or bulimia; or if you have suddenly stopped using alcohol, seizure medication, or a sedative (such as Xanax, Valium, Fiorinal, Klonopin, and others).

Do not use an MAO inhibitor within 14 days before or 14 days after you take Bupropion SR. A dangerous drug interaction could occur. MAO inhibitors include isocarboxazid, linezolid, phenelzine, rasagiline, selegiline, and tranylcypromine.

Do not take Bupropion SR to treat more than one condition at a time. If you take this medicine for depression, do not also take Bupropion SR to quit smoking.

Bupropion SR may cause seizures, especially if you have certain medical conditions or use certain drugs. Tell your doctor about all of your medical conditions and the drugs you use.

Tell your doctor if you have ever had:

a head injury, seizures, or brain or spinal cord tumor; narrow-angle glaucoma; heart disease, high blood pressure, or a heart attack; diabetes; kidney or liver disease (especially cirrhosis); depression, bipolar disorder, or other mental illness; or if you drink alcohol.

Some young people have thoughts about suicide when first taking an antidepressant. Your doctor will need to check your progress at regular visits. Your family or other caregivers should also be alert to changes in your mood or symptoms.

Ask your doctor about taking this medicine if you are pregnant. It is not known whether Bupropion SR will harm an unborn baby. However, you may have a relapse of depression if you stop taking your antidepressant. Tell your doctor right away if you become pregnant. Do not start or stop taking this medicine without your doctor's advice.

If you are pregnant, your name may be listed on a pregnancy registry to track the effects of bupropion on the baby.

It may not be safe to breastfeed while using this medicine. Ask your doctor about any risk.

Bupropion SR is not approved for use by anyone younger than 18 years old.

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Endometrial pathology was more likely to be diagnosed in gynecological symptomatic postmenopausal and premenopausal women with breast carcinoma treated with Tamoxifen. The optimum compositions of solvent to extract chemical substances from green tea and for mobile phase chromatographic analysis were ethyl acetate/ ethanol/dichloromethane (20:5:75 v/v/v) and MeOH/ACN/water (7.5:57.5:35 v/v/v), respectively. The aim of the study was to compare the performance of DA-CPR and attainable skills following CPR training between young and elderly laypersons. The global stability of the steady jetting mode of liquid jets focused by coaxial gas streams is analyzed both theoretically and experimentally. The aim of this study is to explore the effect of remoteness, the shortest path between the subject location and the population center, on hypertension prevalence in a rural region in Japan. Cross-sectional study in a randomly selected, population-based cohort. Although integration of these concepts and techniques in population pharmacokinetic analyses is not only limited to pediatric research, their application allows researchers to overcome some major hurdles frequently encountered in pharmacokinetic studies in pediatrics and, thus, provides the basis for additional clinical pharmacology research in this previously insufficiently studied fraction of the general population.

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Marked Elevation of Plasma Levels of Oxidative Stress-Responsive Apoptosis-Inducing Protein in Dialysis Patients. Laparoscopic management of ruptured heterotopic pregnancy after intrauterine insemination. Cracking the neck is an age-old practice in contravention of its dangerous affects. Caesarean section without medical indications is associated with an increased risk of adverse short-term maternal outcomes: the 2004-2008 WHO Global Survey on Maternal and Perinatal Health. In study 2, we complemented our results with findings from a larger, nonclinical sample of 89 participants that were recruited during an open-house event at the local university. Proponents of one account argue that words have top-down effects on cognitive tasks, and, as such, function as supervisory signals. Problems raised by the study of the treatment of primary tuberculous infection in child. In order to study the treatment of aneurysms, the technique of making experimental aneurysms in laboratory animals must be established. Long-term follow-up studies after endovascular treatment for intracranial aneurysm are still rare and inconclusive. Antisaccade deficits are a well-documented pathophysiological characteristic in schizophrenia.

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Overall, the Normalized Difference Vegetation Index (NDVI) composites from the VGT sensor based on bi-directional compositing method produced vegetation information most closely resembling actual crop conditions. Perceptions of health were measured using the SF-36 Health Survey at baseline, postintervention, and at 6-month follow-up. Rh-catalyzed Denitrogenative Reaction of N-Sulfonyl-1,2,3-triazoles with Isatoic Anhydrides and Oxadiazolones. The objective of this study was to provide a systematic review of published CUAs of healthcare technologies in Brazil. Hematopoiesis at the onset of metamorphosis: terminal differentiation and dissociation of the Drosophila lymph gland. Furthermore, an unanticipated ability of separase to inhibit Cdk1 suggests additional, nonproteolytic functions of separase. Skin samples of unknown infectivity in limited tests gave identical positive or negative results in both steers and Povitsky cultures, but were consistently negative when tested in suckling mice and in prescription-bottle tissue cultures. This review is registered in PROSPERO (registration number: CRD42013005025). Here, we argue that the failure of earlier experiments to detect the integer and fractional quantum Hall effect with a Hall-bar lead geometry is a consequence of the invasive character of voltage probes in mesoscopic samples, which are easily shorted out owing to the formation of hot spots near the edges of the sample. To evaluate the validity of self-reported hysterectomy against the gold standard of uterine visualisation using pelvic ultrasound.

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On the applicability of the decentralized control mechanism extracted from the true slime mold: a robotic case study with a serpentine robot. In particular, Lys-5 acetylation decreases the activity of PRMT1 but increases that of PRMT5. Although the clinical relevance of this pharmacokinetic interaction plavix medication 75mg was not determined in this study, MPA drug monitoring by limited sampling strategies might be helpful during changes in antacid comedication in patients on MMF. We previously reported that angiogenesis function of pulmonary artery endothelial cells (PAECs) is impaired by increased reactive oxygen species formation in a fetal lamb model of intrauterine pulmonary hypertension (IPH). This is the first prospective randomized multi-center trial to compare these strong statins (UMIN Registration No: 000000586).

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