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Calcibloc (Nifedipine)

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Calcibloc is a dihydropyridine calcium channel blocker. Calcibloc is used to: treat high blood pressure (hypertension), prevent chronic stable angina (chest pain). Calcibloc was the first calcium channel blocker to be shown to significantly reduce the development of new overt heart failure in patients with coronary artery disease. Excellent blood-pressure control in recent clinical trials has been shown to result in significant protection against stroke. Calcibloc works by opening up blood vessels in the body to lower blood pressure and improve the supply of blood and oxygen to the heart. Calcium channel blockers do not change the amount of calcium in your blood or bones.

Other names for this medication:
Addos, Anpect, Antrolin, Atanaal, Cardalin, Cardifen, Casanmil, Chronadalate, Cisday, Cobalat, Conducil, Coracten, Coral, Duranifin, Epilat, Fedip, Fenidina, Ficor, Hexadilat, Nicardia, Nidicard, Nifebene, Nifecardia, Nifeclair, Nifed, Nifedip, Nifedipin, Nifezzard, Niften, Nipin, Noviken, Nycopin, Nyefax, Sepamit, Sidalat, Tensopin

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Acticin, Catapres, Zetia, Minocin, Lunesta, Priligy, Zyvox

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Also known as: Nifedipine


Nifedipine is used alone or together with other medicines to treat severe chest pain (angina) or high blood pressure (hypertension). High blood pressure adds to the workload of the heart and arteries. If it continues for a long time, the heart and arteries may not function properly. This can damage the blood vessels of the brain, heart, and kidneys, resulting in a stroke, heart failure, or kidney failure. High blood pressure may also increase the risk of heart attacks. These problems may be less likely to occur if blood pressure is controlled.

Nifedipine is a calcium channel blocker. It works by affecting the movement of calcium into the cells of the heart and blood vessels. As a result, nifedipine relaxes blood vessels and increases the supply of blood and oxygen to the heart while reducing its workload.

This medicine is available only with your doctor's prescription.


This section provides information on the proper use of a number of products that contain nifedipine. It may not be specific to Calcibloc PA 20. Please read with care.

In addition to the use of this medicine, treatment for your high blood pressure may include weight control and changes in the types of foods you eat, especially foods high in sodium (salt). Your doctor will tell you which of these are most important for you. You should check with your doctor before changing your diet.

Many patients who have high blood pressure will not notice any signs of the problem. In fact, many may feel normal. It is very important that you take your medicine exactly as directed and that you keep your appointments with your doctor even if you feel well.

Remember that this medicine will not cure your high blood pressure, but it does help control it. You must continue to take it as directed if you expect to lower your blood pressure and keep it down. You may have to take high blood pressure medicine for the rest of your life. If high blood pressure is not treated, it can cause serious problems such as heart failure, blood vessel disease, stroke, or kidney disease.

Swallow the extended release tablet whole. Do not break, crush, or chew it. It is best to take this tablet on an empty stomach.

If you are taking the extended-release tablets, part of the tablet may pass into your stool after your body has absorbed the medicine. This is normal and nothing to worry about.

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For treatment of chest pain or high blood pressure: For oral dosage form (capsules): Adults—At first, 10 milligrams (mg) three times a day. Your doctor may increase your dose as needed. Children—Use and dose must be determined by your doctor. For oral dosage form (extended-release tablets): Adults—At first, 30 or 60 milligrams (mg) once a day. Your doctor may increase your dose as needed. However, the dose is usually not more than 90 mg once a day. Children—Use and dose must be determined by your doctor.


If you overdose Calcibloc and you don't feel good you should visit your doctor or health care provider immediately.


Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Detailed Nifedipine dosage information

Side effects

The most common side effects associated with Calcibloc are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

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Cell proliferation activity during wound healing was analyzed by proliferating cell nuclear antigen immunohistochemistry (IHC). The hazards of tardive dyskinesia require a rigorous design for any long-term use of neuroleptics. Use of acid enamel biopsy in examinations of enamel mineral content of permanent human teeth with reference to age and environmental conditions. A 75-year-old man with a history of prostatic carcinoma and atypical fibroxanthoma reports a long-standing history of 1-2 mm depressed, hyperkeratotic papules on the palms. Dissecting Low Atmospheric Pressure Stress: Transcriptome Responses to the Components of Hypobaria in Arabidopsis. Preparation of the C3-ms required only small amounts of partially purified C3 and no immunoglobulin or other C components. The remaining 4 patients were at best only slightly improved by either 5-H.T.P. TREATMENT OF TUMORS OF THE INTERNAL ANGLE OF THE EYE BY ACUPUNCTURE WITH CO-60: RESULTS. This overview of the metabolism of the fungicides hexachlorobenzene (HCB) and pentachloronitrobenzene (PCNB) indicates similarities in their pathways of biotransformation. Therefore, the siRNA transport into a cell requires efficient carriers.

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Evidence for two distinct types of postsynaptic alpha-adrenoceptor in vascular smooth muscle in vivo. Low-resolution electron-density and anomalous-scattering-density maps of Chromatium high-potential iron protein. The issues of pre-nosologic diagnostic and effectiveness of treatment of diseases of oral cavity is an actual issue in dentistry. In patients with normal ALT levels, virological non-response to therapy results in new elevations in serum ALT levels in a small minority only. Exogenous hormone therapy to control the estrous cycle of the bitch. A Simple Green Synthesis of Palladium Nanoparticles with Sargassum Alga and Their Electrocatalytic Activities Towards Hydrogen Peroxide. A paired Bagby and Kuslich (BAK) standard cage construct is compared with a paired BAK Proximity construct (Sulzer Spine-Tech, Minneapolis, MN).

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From correlations with extensive data from the medical records, preadmission antibiotic treatment appeared to protect from acousticovestibular damage. Viscoelastic and motile properties of hamster lung and peritoneal macrophages. Sequence analysis of WESR3 protein revealed the presence of highly conserved regions of Mlo gene family. A comparison was made of pillows of various designs and their effects on the flow of air through the respiratory tract of six children who had been found dead in their cots. Cerebral magnetic resonance changes associated with fibromyalgia syndrome. Renoprotection by direct renin inhibition: a systematic review and meta-analysis. Desde el punto de vista neurofisiologico, todos los pacientes presentan formas axonales de tipo sensitivomotoras y las alteraciones de la onda F son el dato mas precoz. IA and RA could produce similar outcomes in treating TMJA regarding to rankylosis and maximum incisal opening. Only after careful evaluation of the individual risk and careful preparations can an MRI be safely performed.

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Differential diagnosis of hypophysial myxedema and primary hyperthyroidism with radioactive iodine and phosphorus tests. The secretolytic agent was associated with significant (P less than 0.05) improvement of lung aerosol distribution in obstructive emphysematous patients, whereas no significant change in lung deposition of the inhaled particles was encountered in the patients with chronic obstructive bronchitis after either drug regimen. Because of their role in detoxification, insect ABC transporters have gained more attention in recent years. Forty-one dogs with visible lameness and radiographic evidence of stifle OA. Improved pacing tolerance of the ischemic human myocardium after administration of carnitine. A double-blind study of melperone and placebo in hospitalized chronic alcoholics in postintoxication phase.

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Activity ranking of quercetin and morin, established by cyclic voltammetry, confirms their activity sequence obtained by EPR results and is also in agreement with the results of conformational analysis. In situ study of water uptake by the seeds, endosperm and husk of barley using infrared spectroscopy. Those researchers who shaped and influenced the ARPA were also instrumental in the development of periodontics in Germany. Quantitative corneal topographies reveal that the ICRS produced a flattening of the anterior surface, a steepening of the posterior surface, meridional differences in the changes in curvature and asphericity, and increased symmetry of the anterior topography. By use of speckle modulation on the object beam of a volume holographic optical correlation system, we show that the sidelobes of the correlation patterns along the vertical direction, as well as those along the horizontal direction, are well suppressed. During the movement of the wheelchair, the user can issue a stop command with the BCI.

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A method for monitoring exposure to ethylene oxide (EO) and propylene oxide (PO) and their corresponding alkenes through the analysis of adducts to N-terminal valine in hemoglobin (Hb) using gas chromatography (GC) and electron-capture detection has been developed. The limitations include the time required and potentially a less formalized and randomized approach than some other processes. Serum samples were collected for the analysis of highly-sensitive troponin-T levels. Secretion of intestinal enzymes by isolated segments of intestines after periods of various duration following denervation. To investigate the influence of deep inspiration breath-hold on the oxygen tension of in-vivo tumours measured using an Eppendorf pO2 histograph.

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Metastatic workup was performed less frequently before salvage vs. This article reviews studies of validated risk-stratification models for delirium. However, the respective effects on long-term stroke risk of fitness and muscle strength in early adulthood are unknown. We show that Sphinx is able to generate high-accuracy predictions and decoy sets enriched with near-native loop conformations, performing better than the ab initio algorithm on which it is based. xanax drug cost Simultaneous integrated boost intensity-modulated radiotherapy for locally advanced non-small cell lung cancer in Chinese population: A retrospective study. Small molecule products consistent with intramolecular termination of diradical oligomers were isolated, and the structures of these molecules suggest how the diradical self-terminates in the absence of chain transfer. Letter: Infectivity of serum containing HBsAg and antibody to e antigen. Systemic lupus erythematosus (SLE) is a chronic inflammatory disease characterized by the production of autoantibodies, formation of immune complexes (IC), and activation of complement that ultimately fuel acute and/or chronic inflammation. Prior LPS treatment of CBA/J adults decreased the ability of their spleen cells to cause fatal graft versus host disease in BALB/c neonates, whereas no difference was found between injection of spleen cells from normal or LPS-treated C3H/HeJ mice.

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We herein report an all-in-one fluorescent semiconducting polymer based far- loxitane 25 mg red to near-infrared (NIR) Pdot nanoprobe for the ratiometric detection of hypochlorous acid (HOCl). We report here three cases of this form of simultaneous HBV infection and PN and describe the particular clinical, virological and evolutive features of the disease. Polymorphisms in the ACE and PAI-1 genes are associated with recurrent spontaneous miscarriages. Red and processed meat intake and risk of colorectal adenomas: a meta-analysis of observational studies. Circadian variation in endotoxaemia and modulatory effects of melatonin. Secondary Analysis of the NCI-60 Whole Exome Sequencing Data Indicates Significant Presence of Propionibacterium acnes Genomic Material in Leukemia (RPMI-8226) and Central Nervous System (SF-295, SF-539, and SNB-19) Cell Lines. However, lifestyle factors which cause age-related decline in UFOV remain poorly understood. The D region of bacteriophage T4 is comprised of six closely linked genes which are situated between 161 kb and 165 kb on the T4 chromosome. Bar workers were recruited before the introduction of the SFL in Scotland and England with the aim of investigating their changes to health, attitudes and exposure as a result of the SFL. All patients reported improved self-control of breathing during speaking, laughing, coughing and physical activity.

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Pilot study testing a European human biomonitoring framework for biomarkers of chemical exposure in children and their mothers: experiences in the UK. Osteoarthritis, labour division, and occupational specialization of the Late Shang China - insights from Yinxu (ca. Nurses not currently screening for sepsis may not place the same value on this alert and find it an annoyance. Observed correlation between serum levels of CRP and soluble TNF receptors suggests the important role of proinflammatory cytokines in stimulating their hepatic synthesis also in patients with breast cancer. This system can be used to excite the resonance frequencies of a cantilever that is either free of the tip-sample interactions or engaged in contact with the sample surface. We searched the Cochrane Central Register of Controlled Trials (The Cochrane Library, issue 2, 2003), MEDLINE (January 1966 to July 2003) and EMBASE (January 1980 to July 2003) for randomized controlled trials comparing NPPV and IPPV weaning. However, despite its beguiling simplicity, there are complications and limitations that accompany pendant drop tensiometry connected with both Bond number (the balance between interfacial tension and gravitational forces) and drop volume. Daytime exposure to bright light, as compared to dim light, decreases sleepiness and improves psychomotor vigilance performance. Although three have been significant research accomplishments, too many people still die of heart and blood vessel diseases.

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Intravenous EMP was administered safely with paclitaxel and carboplatin and produced clinical outcomes similar to the outcomes achieved with the TEC regimen. The interplay between local dynamics and dispersal rates in discrete metapopulation models for homogeneous landscapes is studied. tigrinum melanostictum) involved in North Dakota and Utah (USA) mortality events and spotted salamander (A. As proinflammatory cytokines released during ischaemia are detrimental to the brain, the study aimed to evaluate serum interleukin-18 (IL-18) levels in stroke patients and to investigate the relation between these and epidemiological and clinical data. The modified methods involved the use of glass vessel and inoculation of the autoclaved drug with the yeasts isolated from Dasamularista and Pippaliasava.The quantity of alcohol produced in the glass vessel was more than that in the earthen pot by classical method. Eight different measures were calculated to quantitatively analyze word-word relationships: 1) Associative strength of the first associate, 2) Associative strength of the second associate, 3) Sum of associative strength of first two associates, 4) Difference in associative strength between first two associates, 5) Number of different associates, 6) Blank responses, 7) Idiosyncratic responses, and 8) Cue validity of the first associate. PUMA (p53 upregulated modulator of apoptosis), a member of the B-cell lymphoma 2 (Bcl-2) protein family, is a pro-apoptotic protein. The patient had pancytopenia and his marrow was hyperplastic with erythrophagocytosis by myeloid cells of various stages, including myeloblasts. The precise roles of these hormone factors in the regulation of growth hormone secretion, somatomedin production and tissue growth, particularly the cartilage, remain to be completely elucidated. It is recommended that clinicians use the full WCST with children, unless at least four categories are reached in the first deck.

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The levo-isomer and racemic bucumolol were capable of suppressing aconitine-induced atrial arrhythmia, while the dextro-isomer was less effective. Bronchospasm: an early manifestation of pulmonary embolism during and after anesthesia. Trans-Scaphoid Perilunate Dislocation: Union of an Extruded Scaphoid Proximal Pole Fragment. It is hoped that advances in endomyocardial biopsy will lead to a greater ability of physicians to diagnose and treat cardiac disease. This is particularly important for the adequate identification of the high-risk MM group, which does not benefit from any of the current therapies, and novel approaches albenza dosing pinworm need to be proposed. Autoindicating optical properties of laccase as the base of an optical biosensor film for phenol determination.

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These studies highlight the remarkable diversity of pathogen strategies for trafficking to the brain and will ultimately contribute to an improved ability to combat life-threatening CNS disease. Atropine-resistant spasms due to excitation of non-cholinergic neurones in guinea-pig myenteric plexus. Using these mice, we found that the AM-RAMP2 system is a key determinant of vascular integrity and can bactrim make you have a yeast infection homeostasis from prenatal stages through adulthood. During therapy with hydralazine, there were no new symptoms nor exacerbation of pre-existing symptoms attributable to systemic lupus. Our results confirm the critical role of the C-terminal region of tropoelastin in elastic fiber assembly and suggest tissue-specific differences in the elastin assembly pathway. The pH-rate profiles for the hydrolysis of the derivatives were derived at 60 degrees C.

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