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Calmef (Alprazolam)
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Calmef

Calmef is used to treat anxiety and panic disorders. It belongs to a class of medications called benzodiazepines which act on the brain and nerves (central nervous system) to produce a calming effect. It works by enhancing the effects of a certain natural chemical in the body (GABA). Calmef is mostly used to treat anxiety disorders, panic disorders, and nausea due to chemotherapy. Calmef may also be indicated for the treatment of generalized anxiety disorder, as well as for the treatment of anxiety conditions with co-morbid depression. The FDA label advises that the physician should periodically reassess the usefulness of the drug.

Other names for this medication:
Alamflu, Alpanol, Alpramax, Alzotime, Ambulax, Anxizam, Ateez, Belfa, Berest, Censir, Endolam, Erazol, Fluzolam, Hipose, Manzolam, Mebrin, Mentolift, Morecalm, Normatine, Pacyl, Parazolam, Plaxid, Pranol, Stresnil, Tenscure, Tryzo, Zallpam, Zenax, Zoloid, Zolyde, Zopain

Similar Products:
Levlen, Chloromycetin, Yasmin, Amethopterin, Ovral, Lexapro, Benicar, Evista, Trileptal

Also known as: Alprazolam

Description

Calmef is a benzodiazepine (ben-zoe-dye-AZE-eh-peen). Alprazolam affects chemicals in the brain that may be unbalanced in people with anxiety. Calmef is used to treat anxiety disorders, panic disorders, and anxiety caused by depression.

You should not use Calmef if you have narrow-angle glaucoma, if you also take itraconazole or ketoconazole, or if you are allergic to Calmef or similar medicines (Valium, Ativan, Tranxene, and others).

Alprazolam may be habit-forming. Misuse of habit-forming medicine can cause addiction, overdose, or death.

Do not drink alcohol while taking Calmef. This medication can increase the effects of alcohol. Alprazolam may be habit-forming and should be used only by the person for whom it was prescribed. Keep the medication in a secure place where others cannot get to it.

Dosage

Usual Adult Dose for Anxiety:

Immediate-release tablets: 0.25 to 0.5 mg orally administered 3 times a day -Maximum dose: 4 mg/day

Usual Adult Dose for Panic Disorder:

Immediate-release tablets: 0.5 mg orally administered 3 times a day -Maximum dose: 10 mg/day Extended-release tablets: -Initial dose: 0.5 to 1 mg orally once a day -Maintenance dose: 3 to 6 mg orally per day, preferably in the morning -Maximum dose: 10 mg/day Comments: -The lowest possible effective dose should be administered and the need for continued treatment reassessed frequently. -Dosage should be reduced gradually when discontinuing therapy or when decreasing the daily dosage. -The daily dosage may be decreased by no more than 0.5 mg every 3 days; however, some patients may require an even slower dosage reduction. -The dose of extended-release tablets may be increased at intervals of 3 to 4 days in increments of no more than 1 mg per day. -The times of administration should be distributed as evenly as possible throughout the waking hours.

Usual Geriatric Dose for Anxiety:

Elderly or debilitated patients: Immediate-release tablets: 0.25 mg orally administered 2 or 3 times a day.

Usual Geriatric Dose for Panic Disorder:

Elderly or debilitated patients: Immediate-release tablets: -Initial dose: 0.25 mg orally administered 2 or 3 times a day Extended-release tablets: -Initial dose: 0.5 mg orally once a day Comments: -If side effects develop, the dose may be lowered. -The lowest possible effective dose should be administered and the need for continued treatment reassessed frequently. -Dosage should be reduced gradually when discontinuing therapy or when decreasing the daily dosage.

Detailed Calmef dosage information

Overdose

Seek emergency medical attention if you think you have used too much of this medicine. An overdose of Calmef XR can be fatal.

Overdose symptoms may include extreme drowsiness, confusion, muscle weakness, loss of balance or coordination, feeling light-headed, fainting, and coma.

Storage

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

It is very important to protect the orally disintegrating tablets from moisture. Remove and throw away any cotton packaging from the medicine bottle when you first use the medicine.

Detailed Calmef XR dosage information

Side effects

The most common side effects associated with Calmef are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Do not use Calmef XR if you have:

narrow-angle glaucoma; if you are also taking itraconazole (Sporanox) or ketoconazole (Nizoral); or if you are allergic to alprazolam or to other benzodiazepines, such as chlordiazepoxide (Librium), clorazepate (Tranxene), diazepam (Valium), lorazepam (Ativan), or oxazepam (Serax).

Before taking Calmef XR, tell your doctor if you are allergic to any drugs, or if you have:

asthma, emphysema, bronchitis, chronic obstructive pulmonary disorder (COPD), or other breathing problems; glaucoma; kidney or liver disease (especially alcoholic liver disease); a history of depression or suicidal thoughts or behavior; or a history of drug or alcohol addiction.

If you have any of these conditions, you may need a dose adjustment or special tests to safely take this medication.

It is dangerous to try and purchase Calmef XR on the Internet or from vendors outside of the United States. Medications distributed from Internet sales may contain dangerous ingredients, or may not be distributed by a licensed pharmacy. Samples of alprazolam purchased on the Internet have been found to contain haloperidol (Haldol), a potent antipsychotic drug with dangerous side effects. For more information, contact the U.S. Food and Drug Administration (FDA) or visit www.fda.gov/buyonlineguide

FDA pregnancy category D. Calmef XR can cause birth defects in an unborn baby. Do not use Calmef XR without your doctor's consent if you are pregnant. Tell your doctor if you become pregnant during treatment. Use an effective form of birth control while you are using this medication. Alprazolam can pass into breast milk and may harm a nursing baby. Do not use Calmef XR without telling your doctor if you are breast-feeding a baby.

The sedative effects of Calmef XR may last longer in older adults. Accidental falls are common in elderly patients who take benzodiazepines. Use caution to avoid falling or accidental injury while you are taking Calmef XR. Do not give this medication to anyone under 18 years old.

Calmef XR pregnancy and breastfeeding warnings (more detail)

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Use of immunogold labelling with scanning electron microscopy to identify phytopathogenic bacteria on leaf surfaces. Preliminary report on the effect of urethral diverticulum magnetic resonance imaging configuration on the incidence of new onset urodynamic stress urinary incontinence following excision. Transformation to melanoma occurs when genes involved in controlling senescence are mutated or silenced and cells reacquire the capacity to proliferate. We aimed to test whether stimulation of right DLPFC would modify the activation pattern of the neural circuit underlying decision making during the DD task and influence discounting behavior. Human recombinant erythropoietin therapy in a cat with chronic renal failure.

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Four different mathematical models were evaluated: 1) a saucer-shaped non-carious cervical lesion restored with a composite without a hybrid layer, 2) a saucer-shaped non-carious cervical lesion restored with a composite with a hybrid layer, 3) a wedge-shaped non-carious cervical lesion restored with a composite without a hybrid layer, and 4) a wedge-shaped non-carious cervical lesion restored with a composite with a hybrid layer. To develop a new oncolytic herpes simplex virus (oHSV) for glioblastoma (GBM) therapy that will be effective in glioblastoma stem cells (GSC), an important and untargeted component of GBM. The in vivo production of Pf phage was also associated with reduced lung injury, reduced neutrophil recruitment, and lower cytokine levels. The results suggest that locking the acceptor extremity, the anticodon loop, and the D-loop of tRNA on the catalytic, anticodon-binding, and Add-1 domains of ArgRS also requires some flexibility of the tRNA molecule, provided by G:U base pairs, to achieve the productive conformation of the active site of the enzyme by induced fit. Studies that provide solid evidence of the effectiveness of different airway clearance techniques in patients with COPD are rather scarce. The results suggest that external source monitoring bias may not be central to the cognitive processes underlying hallucinations early in the course of psychotic illness.

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Future studies should further explore the underlying causes and the potential impacts of these sleep differences. We also describe the various sources of ROS in cancer and their role in tumor heterogeneity. Uranium Isotope Fractionation during Adsorption, (Co)precipitation, and Biotic Reduction. In multivariate analysis, lower birthweight and prenatal diagnosis had a significant impact on survival. The phenograms derived from the different probes differed in topology and, on the basis of bootstrap analysis, were not equally robust. Overall, two routes have been developed from a readily prepared bicyclic phosphate (4 steps), a 13-step route and a more efficient 9-step sequence relying on regioselective esterification of a key diol. Male and female parents/caregivers of 35 children with PKU and 35 control parents, completed a neophobia and food frequency questionnaire for comparison using the same questionnaires that they completed for their children. Suicide attempts and ideation are higher in cancer patients compared to the control group.

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Disease in the upper meatus and the posterior portion of the middle meatus strongly affects olfactory function. This requires further investigations to explain this unusual departure from our conventional wisdom of curvature-induced enhancement. Unemployment and psychosocial outcomes to age 30: A fixed-effects regression analysis. Due to the sensitive character of genetic information, protecting privacy and keeping confidentiality become important topics. Performance in assessment: consensus statement and recommendations from the Ottawa conference. It is a centrally mediated disorder of unknown aetiology and manifested by a sustained contraction of masticatory muscles, involving one or both lateral pterygoids, and pushing the mandible forward. One hundred and fifty patients with lung cancer treated surgically from 2000 were enrolled randomly. Maternofetal pharmacokinetics of a gadolinium chelate contrast agent in mice. In agreement with previous studies, holdings also differed in both the number of contacts as well as with what holding types contact occurred with. The theory and experimental results of a computation time-saving mirror image suppression method in Fourier-domain optical coherence tomography, which utilizes the property of reversed system phase shift between the real and mirror images, for differentiating one from the other are demonstrated.

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A RhoGDP dissociation inhibitor spatially regulates growth in root hair cells. To establish a reversed-phase high-performance liquid chromatographic (RP-HPLC) method for determination of phloridzin content. The Bdellovibrio and like organisms, unlike viruses, are bacteria that can efficiently infect and grow in prey which are in stationary phase. Structural basis for the prion-like MAVS filaments in antiviral innate immunity. Adverse events and intravenous versus oral bisphosphonate use in patients with osteoporosis and cancer in the U.S. Thirty-five subjects affected by calcifying tendinitis of the shoulder were examined. Microbiological safety of porcine islets: comparison with source pig. Chlorinated hydrocarbon insecticides accumulate in body fat depots and cause both liver and kidney damage while being metabolized and excreted. We examined the use of natural herbs from the 2002 National Health Interview Survey (NHIS).

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The results allow the use of ECOHIS to be recommended for clinical research in oral health-related quality of life in young children with minor modifications. In multiple current applications, such as three-dimensional, time-resolved or cluster imaging, high densities of fluorophore emissions are common. It is unclear if infants born following prelabour premature rupture of the membranes mount an adequate anti-inflammatory response. The results show that the procedure is simple and sensitive and that it can be employed for the simultaneous determination of AA and its related compounds in foods and beverages. These findings suggest that ER stress participates in the degeneration of Purkinje cells and that activation of microglia accelerates Purkinje cell death in pcd mice. Sham rats and TBI rats were given either olive oil or fish oil by oral gavage and were subject to cerebral microdialysis. In contrast, sEPSCs and eEPSCs in RAD interneurons did not change after KA treatment. Tear film break- theolair 250 mg hond up time test, Schirmer-I test, and conjunctival impression cytology analysis were performed on all patients at baseline and after 1 and 3 months. Overall, this study showed that multiple risk-related factors are associated with having older friends in eighth grade.

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Acute rejection has been identified as the primary risk factor for BOS, but the impact of minimal acute rejection, especially a solitary episode, has usually been discounted as clinically insignificant. Anti-cancer therapeutic mAb are claimed to bind these cell-surface molecules on viable cancer cells: therefore, it is necessary to produce mAb recognizing epitopes on the extracellular domains of native but not denatured proteins. Though the physical appearance of these patients is characteristic, there is little emphasis on the characteristic radiological features. Is the prostaglandin e2 pathway in primary graft dysfunction ready for prime time?. The effects of radiation on a variety of different materials is a growing research area that can create safer techniques that reduce radiation damage and increase cost-effectiveness in the future. The teeth were then divided into two groups according to the method of caries removal. However, in the preterm infant, defining hypoxic-ischemic injury (HII), its clinical course, monitoring, and outcomes remains complex.

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