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Cardoplus (Losartan)
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Cardoplus

Cardoplus is hypotension medication which specifically blocks angiotensin II receptors, decreases the total peripheral resistance, concentration of aldosteron in blood, arterial pressure, pressure in pulmonary circulation, and has a diuretic effect. The medication is used to treat hypertension, left ventricular hypertrophy (increase in muscle) and diabetic nephropathy.

Other names for this medication:
Arapres, Aratan, Asart, Cardoplus, Corus, Cosart, Covance, Cozaarex, Cozzar, Fensartan, Klosartan, Lacine, Lepitrin, Lifezar, Lohyp, Loplac, Lopress, Lortaan, Losakind, Losamet, Losap, Losapot, Losaprex, Losartan, Losartil, Losatan, Losium, Lostad, Lostankal, Lotan, Lyosan, Mozartan, Niten, Normatens, Omnitan, Osartan, Ozarium, Prelow, Rasoltan, Repace, Resilo, Sanipresin, Satoren, Sortal, Sortiva, Temisartan, Tensaar, Tensiohess, Tozaar

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Also known as: Losartan

Description

Cardoplus is indicated for the treatment of hypertension in adults and pediatric patients 6 years of age and older, to lower blood pressure. Lowering blood pressure lowers the risk of fatal and nonfatal cardiovascular (CV) events, primarily strokes and myocardial infarction. These benefits have been seen in controlled trials of antihypertensive drugs from a wide variety of pharmacologic classes including losartan.

Control of high blood pressure should be part of comprehensive cardiovascular risk management, including, as appropriate, lipid control, diabetes management, antithrombotic therapy, smoking cessation, exercise, and limited sodium intake. Many patients will require more than 1 drug to achieve blood pressure goals. For specific advice on goals and management

Cardoplus is indicated to reduce the risk of stroke in patients with hypertension and left ventricular hypertrophy, but there is evidence that this benefit does not apply to Black patients

Cardoplus is indicated for the treatment of diabetic nephropathy with an elevated serum creatinine and proteinuria in patients with type 2 diabetes and a history of hypertension. In this population, Cardoplus reduces the rate of progression of nephropathy as measured by the occurrence of doubling of serum creatinine or end stage renal disease

Dosage

Usual Adult Dose for Diabetic Nephropathy:

Initial dose: 50 mg orally once a day Maximum dose: 100 mg orally once a day Comments: -If hypertensive patients with left ventricular hypertrophy or type 2 diabetic nephropathy patients require titration from initial dose, increase to 100 mg orally once a day. -Antihypertension is substantially present within 1 week but in some studies the maximal effect occurred in 3 to 6 weeks. Uses: -Treatment of hypertension. -To reduce the risk of stroke in patients with hypertension and left ventricular hypertrophy. -Treatment of diabetic nephropathy with an elevated serum creatinine and proteinuria (urinary albumin to creatinine ratio 300 mg/g or greater) in patients with type 2 diabetes and a history of hypertension.

Usual Adult Dose for Hypertension:

Initial dose: 50 mg orally once a day Maximum dose: 100 mg orally once a day Comments: -If hypertensive patients with left ventricular hypertrophy or type 2 diabetic nephropathy patients require titration from initial dose, increase to 100 mg orally once a day. -Antihypertension is substantially present within 1 week but in some studies the maximal effect occurred in 3 to 6 weeks. Uses: -Treatment of hypertension. -To reduce the risk of stroke in patients with hypertension and left ventricular hypertrophy. -Treatment of diabetic nephropathy with an elevated serum creatinine and proteinuria (urinary albumin to creatinine ratio 300 mg/g or greater) in patients with type 2 diabetes and a history of hypertension.

Usual Pediatric Dose for Hypertension:

6 Years or Older: Initial dose: 0.7 mg/kg orally once a day (up to 50 mg total) Comments: -May be given as a tablet or suspension. -Doses above 1.4 mg/kg (or 100 mg) daily have not been studied in pediatric patients.

Detailed Cardoplus dosage information

Overdose

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Storage

Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) away from moisture, light and heat. Keep container tightly closed. Throw away any unused medicine after the expiration date. Keep out of the reach of children in a container that small children cannot open.

Side effects

The most common side effects associated with Cardoplus are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Do not take Cardoplus if you are allergic to Cardoplus components. Do not take Cardoplus if you're pregnant or you plan to have a baby, or you are a nursing mother. Cardoplus can harm your baby. Do not use Cardoplus if you are taking salt substitutes or potassium supplements, other blood pressure medicine, diuretic (water pill). It can be dangerous to use Cardoplus if you suffer from or have a history of liver disease, kidney disease, heart failure. If you want to achieve most effective results without any side effects it is better to avoid alcohol. Avoid machine driving. Do not stop taking Cardoplus suddenly.

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What front-line CBO staff can tell us about culturally anchored theories of behavior change in HIV prevention for Asian/Pacific Islanders. Intravenous tolbutamide administration for the adjustment of senile diabetics during surgery. In type 1 diabetic patients, insulin secretory capacity, meals and physical activity correlate with glycemic variability. However, the prevalence, and thus the population-attributable risk, of mild hypertension is far greater than that of the more severe forms of hypertension. Randomized phase II trial of everolimus in combination with tamoxifen in patients with hormone receptor-positive, human epidermal growth factor receptor 2-negative metastatic breast cancer with prior exposure to aromatase inhibitors: a GINECO study.

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The efficiency of photoreactions decreased with an increase in the wavelength of the irradiating light. The production of N-linked recombinant glycoproteins is possible in a variety of biotechnology host cells, and more recently in the bacterial workhorse, Escherichia coli. Suppression of AD and AI CaP cell growth by piceatannol was accompanied by cell cycle blockade in G(1)/S and S phases for LNCaP and PC-3 and induction of apoptosis in DU145 cells. The necessary stability and convergence conditions are briefly exposed. In this Letter we propose a new monojetlike search for light top squarks, optimized for the four-body decay mode, in which at least one b-tagged jet is required. The appreciation of the role of apoptosis in the vast majority of diseases affecting humans has revolutionized the discovery and development of drugs targeting inflammation and oncology.

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