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Colcrys (Colchicine)
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Colcrys

Colcrys is used to prevent gout attacks (sudden, severe pain in one or more joints caused by abnormally high levels of a substance called uric acid in the blood) in adults. Colcrys is also used to relieve the pain of gout attacks when they occur.

Other names for this medication:
Colchicindon, Colchicine, Coljoy, Goutnil, Zycolchin

Similar Products:
Decadron, Clarinex, Pepcid, Zebeta, Detrol, Avodart

Also known as: Colchicine

Description

{name} (colchicine) affects the way the body responds to uric acid crystals, which reduces swelling and pain.

Because colchicine was developed prior to federal regulations requiring FDA review of all marketed drug products, not all uses for colchicine have been approved by the FDA. As of 2009, {name} is the only brand of colchicine that has been approved by the FDA.

The {name} brand of colchicine is FDA-approved to treat gout in adults, and to treat a genetic condition called Familial Mediterranean Fever in adults and children who are at least 4 years old.

Generic forms of colchicine have been used to treat or prevent attacks of gout, or to treat symptoms of Behcets syndrome (such as swelling, redness, warmth, and pain).

{name} is not a cure for gouty arthritis or Behcets syndrome, and it will not prevent these diseases from progressing. {name} should not be used as a routine pain medication for other conditions.

Dosage

Take Colcrys exactly as prescribed by your doctor. Follow all directions on your prescription label. Do not take this medicine in larger or smaller amounts or for longer than recommended.

Do not purchase colchicine on the Internet or from vendors outside of the United States. Using this medication improperly or without the advice of a doctor can result in serious side effects or death.

Colcrys can be taken with or without food.

To treat a gout attack, for best results take Colcrys at the first sign of the attack. The longer you wait to start taking the medication, the less effective it may be.

You may need to take a second lower dose of Colcrys 1 hour after the first dose if you still have gout pain. Follow your doctor's instructions.

Your dose will depend on the reason you are taking this medicine. Colchicine doses for gout and Mediterranean fever are different.

Do not stop using Colcrys unless your doctor tells you to, even if you feel fine.

Call your doctor if your symptoms do not improve, or if they get worse.

If you use this medicine long-term, you may need frequent medical tests.

Store at room temperature away from moisture, heat, and light. Keep the bottle tightly closed when not in use.

Detailed Colcrys dosage information

Overdose

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose of colchicine can be fatal.

Overdose symptoms may include diarrhea, nausea, vomiting, stomach pain, muscle weakness, little or no urinating, numbness or tingling, weak pulse, slow heart rate, weak or shallow breathing, or fainting.

Storage

Store at a room temperature between 4 and 30 degrees C (39 and 86 degrees F) away from moisture, light and heat. Throw away the after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Colcrys are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Grapefruit and grapefruit juice may interact with colchicine and lead to unwanted side effects. Avoid the use of grapefruit products while taking Colcrys.

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Known VDR polymorphisms are not associated with bone mineral density measures in pediatric Cushing disease. Pathology of congenital heart diseases: current status and prospects. This study confirms that the lingual pedicle of soft tissue is adequate to maintain the viability of the superiorly repositioned alveolus or segment and to allow rapid remodeling of the autogenous bone graft. Indole-3-carbinol prevents diet-induced obesity through modulation of multiple genes related to adipogenesis, thermogenesis or inflammation in the visceral adipose tissue of mice. Spatiotemporal expression and transcriptional perturbations by long noncoding RNAs in the mouse brain. Moreover, the lungs of B6D2/F(1) mice infected with the DeltanrdZ mutant had bacterial loads comparable to those of lungs infected with the parental wild-type strain, which argues against the hypothesis that nrdZ plays a significant role in the virulence of M. This was achieved by affinity-labeling 50S subunits with N-bromoacetyl puromycin and treating the labeled subunits with an antibody specific for the N6,N6-dimethyladenosine moiety of puromycin. On the basis of their killer effect, studies have been carried out on the differentiation of fungi and some bacteria by using YKT as epidemiological tools. Genetic and biochemical experiments indicate that the region controlling STHM synthesis is present on the insert. Localization of osteopontin in oviduct tissue and eggshell during different stages of the avian egg laying cycle.

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