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Detrol (Tolterodine)

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Detrol is a medicine used to treat symptoms of an overactive bladder. These can include: a sudden and urgent need to pee (urinary urgency) needing to pee more often than usual (urinary frequency).

Other names for this medication:
Bapter, Concys, Detrusitol, Dezrolala, Flochek, Roliten, Terol, Tolter, Tolterodine, Uftol, Uridin, Urotel

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Also known as: Tolterodine


{name} LA is used in adults to treat overactive bladder with symptoms of urinary frequency, urgency, and incontinence (urine leakage).


Usual Adult Dose for Urinary Incontinence:

Immediate release tablets: -Initial dose: 2 mg orally 2 times a day -Maintenance dose: 1 to 2 mg orally 2 times a day, depending on patient response and tolerability Extended release capsules: -Initial dose: 4 mg orally once a day -Maintenance dose: 2 to 4 mg orally once a day, depending on patient response and tolerability Comments: -This drug can be taken with or without food. -The extended release formulation should be swallowed whole. Use: For the treatment of overactive bladder (OAB) with symptoms of urge urinary incontinence, urgency, and frequency

Usual Adult Dose for Urinary Frequency:

Immediate release tablets: -Initial dose: 2 mg orally 2 times a day -Maintenance dose: 1 to 2 mg orally 2 times a day, depending on patient response and tolerability Extended release capsules: -Initial dose: 4 mg orally once a day -Maintenance dose: 2 to 4 mg orally once a day, depending on patient response and tolerability Comments: -This drug can be taken with or without food. -The extended release formulation should be swallowed whole. Use: For the treatment of overactive bladder (OAB) with symptoms of urge urinary incontinence, urgency, and frequency

Detailed Detrol dosage information


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.


Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) away from moisture and heat. Throw away any unused medicine after the expiration date. Keep out of reach of children.

Side effects

The most common side effects associated with Detrol are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Do not take Detrol if you are allergic to Detrol components. Do not take Detrol while you are pregnant or have nurseling. Avoid alcohol. Take Detrol with care if you are taking bepridil (Vascor),cisapride (Propulsid);chloroquine (Arelan) or halofantrine (Halfan);cyclosporine (Gengraf, Neoral, Sandimmune); narcotic medication such as levomethadyl (Orlaam); or methadone (Dolophine, Methadose);pentamidine (NebuPent, Pentam);vinblastine (Velban);antibiotics such as azithromycin (Zithromax), clarithromycin (Biaxin), dirithromycin (Dynabac), erythromycin (E-Mycin, E.E.S., Erythrocin, Ery-Tab), pentamidine (NebuPent, Pentam), sparfloxacin (Zagam), telithromycin (Ketek);medicines to treat psychiatric disorder, such as chlorpromazine (Thorazine), mesoridazine (Serentil) pimozide (Orap), or thioridazine (Mellaril); or heart rhythm medicine such as amiodarone (Cordarone, Pacerone), dofetilide (Tikosyn), disopyramide (Norpace), procainamide (Procan, Pronestyl), quinidine (Cardioquin, Quinaglute), or sotalol (Betapace), arsenic trioxide (Trisenox); haloperidol (Haldol), droperidol (Inapsine). You should be careful when you are driving or operating machinery. It can be dangerous to use Detrol if you suffer from or have a history of a blockage in your stomach or intestines, untreated or uncontrolled glaucoma, kidney disease, "Long QT syndrome", blockage of the urinary tract (difficulty urinating), liver disease. It can be dangerous to stop Detrol taking suddenly.

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UGT75L6 and UGT94E5 mediate sequential glucosylation of crocetin to crocin in Gardenia jasminoides. Autonomic nerves, amine receptors and their effects on cerebral blood flow. Clinical evaluation is an excellent test for the evaluation of the position of an IUD and routine TVU is not indicated for this purpose. Reduction in the amount of carbohydrate material in the epithelial cells of the mid-gut is associated with change in intracellular localization (by vanishing from definite sites, not by migration). Assessment of this association in juvenile idiopathic arthritis (JIA) is complicated by age-dependent IgG glycan variation. This indicates that the material in leukaemic sera responsible for the in vitro block of antibody mediated cytotoxicity was p30. Experimental and clinical evaluation of chlorcyclizine as an antitussive. Prescribing indicators: what can Canada learn from European countries?. Astrocytes also are connected with each other and with neurons by juctions characterized by wide (250 A) gaps containing opaque gap material and by dense material adhering to the inner surfaces of the plasma membranes.

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Does the Relative Strength of Grouping Principles Modulate the Interactions between them?. In addition to lifestyle modification and dietary salt restriction, treatment may need to be individualized based on co-morbidities. Effect of overpressure and pulse repetition frequency on cavitation in shock wave lithotripsy. Waking cortisol was negatively associated with neuroticism, but positively associated with physiological reactivity to loud tones and fear conditioning when assessed during training. Light and electron microscopic differentiation of amyloid and colloid or hyaline bodies. TURN Score Predicts 90-day Outcome in Acute Ischemic Stroke Patients After IV Thrombolysis. We found no significant impact of the method on either individual performance (growth and reproduction) or population development (abundance and structure) of daphnids in comparison to the previously used method for data gathering (sieving, counting and length measurement of a subsample via microscopy).

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A factor modulating the endogenous electrical activity of the bursting neuron. It was shown that one of the mechanisms of antiulcer preventive effect of the multistrain probiotics is the restoration of pro/antioxidant balance in the GM under the stress action. Epidemiological and genealogical studies on its occurrence in the Bern canton in 1966. A 69-year-old man presented with symmetric erythematous, hyperpigmented, and ivory-colored plaques on the trunk and extremities. Prebiotic Galactooligosaccharide Metabolism by Probiotic Lactobacilli and Bifidobacteria. There was a fairly low proportion of patients from each group who were on the drug in any given year, and a fairly wide range of total dosage received. To determine whether pretreatment of skin with erbium:YAG (Er:YAG) laser-assisted delivery facilitates the penetration of lidocaine cream to provide anesthesia suitable for needlesticks after just 5 minutes. The same applied to abnormalities of glucose tolerance when the 125 men with known non-insulin-treated diabetes at baseline were added to the group.

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A distinction between the anticoagulant and antithrombotic effects of dicumarol. The purpose of this study is to develop and evaluate the psychometric properties of an instrument to compare the influences of healthcare career choice with perceptions of nursing as a career choice. The article presents a short information about the Resolution of Ukr.SSR Soviet of Ministers on establishing the nominal premium of Presidium the Academy of Sciences of Ukr.SSR (of NAS of Ukraine, now) in the field of biochemistry and molecular biology dedicated to the famous scientists, founder of the Ukrainian biochemical school and the Institute of Biochemistry named after him--academician O. Research on the mosquitoes of Portugal (Diptera, Culicidae) I--Four new culicine records. It is revealed that the local maxima in the profit landscape are spread in the form of a fractal structure.

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