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Fasigyn (Tinidazole)

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Fasigyn is a drug used against protozoan infections. It is widely known throughout Europe and the developing world as a treatment for a variety of anaerobic amoebic and bacterial infections. It was developed in 1972 and is a prominent member of the nitroimidazole antibiotic class.

Other names for this medication:
Simplotan, Tindamax, Tinidazole

Similar Products:
Nolvadex, Provera, Detrol, Xenical, Catapres, Atarax, Cialis

Also known as: Tinidazole


Fasigyn 500mg film-coated tablets contain 500mg of the active substance tinidazole. This medicine is an anti-infective agent. It is used to treat a variety of bacterial infections including: infections of the skin, blood, chest, lung, genitals or womb lining, an infection associated with stomach ulcers in combination with other drugs, infections caused by organisms called protozoa, such as amoebiasis and giardiasis (stomach infections) and trichomoniasis (a genital infection), vaginal infections (vaginitis) and gum infections (gingivitis).

It is also used before certain surgical operations to prevent bacterial infections developing.

You should ask your doctor if you are unsure why you have been given this medicine.


Always take this medicine exactly as your doctor has told you. Check with your doctor or pharmacist if you are not sure.

Take Fasigyn with a glass of water during or after a meal. Swallow the tablets whole. It is best to take the medicine at the same time each day.

For bacterial infections, this medicine is not recommended for use in children less than 12 years as it has not been tested in this age group.

For protozoal infections, Fasigyn 500mg film-coated tablets can be used in children and has not been shown to cause any different side effects or more problems than it does in adults.

The dose and length of treatment depends upon the infection being treated. If you are on dialysis, your doctor may prescribe a different dose.

The doses most commonly used for the different infections are shown in the table below:

For treating the infection associated with stomach ulcers. The usual dose is 1 tablet (500mg) taken twice a day. Your doctor will probably prescribe two other medicines to be taken with Fasigyn 500mg film-coated tablets. Treatment with the three medicines together will usually be for 1 week.

For treating most bacterial infections. The usual dose is 4 tablets (2g) on the first day then 2 tablets (1g) once a day or 1 tablet (500mg) twice a day. The usual length of treatment is 5 to 6 days.

For treating bacterial vaginitis (a vaginal infection) and acute ulcerative gingivitis (a gum infection). The usual dose is 4 tablets (2g) given as a single dose. For vaginitis you may be given 4 tablets (2g) on two consecutive days.

For preventing bacterial infections after surgery. Usually 4 tablets (2g) are given as a single dose about 12 hours before surgery.

For treating protozoal infections. For treating intestinal amoebiasis (a stomach infection). Adult: The usual dose is 4 tablets (2g) once a day for 2 to 3 days. Child: The usual dose is 50 to 60mg/kg of body weight once a day for 3 days.

For treating amoebic involvement of the liver (a liver infection). Adult: The usual dose is 3 to 4 tablets (1.5 to 2g) once a day for 3 to 6 days. Child: The usual dose is 50 to 60mg/kg of body weight once a day for 5 days.

For treating giardiasis (an abdominal infection) and trichomoniasis (an infection of the sex organs in males and females). Adult: The usual dose is 4 tablets (2g) given as a single dose. Child: The usual dose is 50 to-75mg/kg of body weight given as a single dose.

Your doctor will calculate the dose required for a child and may repeat the dose once if the infection has not cleared up completely.


If you take too much of this medicine tell your doctor or contact your nearest hospital casualty department immediately. Take any remaining tablets with you.


Keep Fasigyn in its original packaging until it is time to use it. If you take Fasigyn out of its packaging, it may not keep as well.

Keep your Fasigyn in a cool, dry place where it stays below 25 degrees C.

Do not store Fasigyn or any other medicine in the bathroom or near a sink. Do not leave it in the car or on a window sill. Heat and dampness can destroy some medicines.

Keep your Fasigyn where young children cannot reach it. A locked cupboard at least one and a half metres above the ground is a good place to store medicines.

Side effects

The most common side effects associated with Fasigyn are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Do not take Fasigyn if you are allergic to: Fasigyn, any ingredients listed at the end of the leaflet, or related medicines such as Simplotan, Flagyl, Metrogyl and Metozine (not all brands given). If you are not sure if you are allergic to any of the above, ask your doctor. Symptoms of an allergic reaction include: asthma, wheezing or shortness of breath, swelling of the face, lips or tongue which may lead to difficulty swallowing or breathing, hives, itching, skin rash or redness of skin, fainting, light-headedness.

Do not take Fasigyn if you have a history of any blood disorder.

Do not take Fasigyn if you have any disease of the brain, spinal cord or nerves.

Do not take Fasigyn if you are pregnant or intend to become pregnant. Your doctor will discuss the risks and benefits of taking Fasigyn during pregnancy (pregnancy up to four months).

If you are a woman of child-bearing age, make sure you do not become pregnant while taking Fasigyn.

Do not take Fasigyn if you are breastfeeding. Like many other medicines, Fasigyn passes into breast milk and may harm your baby.

Do not breastfeed your baby while taking, and until at least three days after stopping Fasigyn.

If you are not sure whether you should be taking Fasigyn, talk to your doctor.

Do not take Fasigyn if the expiry date (EXP) or use by date printed on the pack has passed. If you take this medicine after this date, it may not work.

Do not take Fasigyn if the packaging is torn or shows signs of tampering. If this is the case, return it to your pharmacist.

If you are not sure whether you should start taking Fasigyn, talk to your doctor.

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This novel strategy reveals a new horizon in the improvement of gene therapy, based on stem cell transplantation in neurodegenerative diseases. Management of FNT is largely based on the clinicoradiological picture. Views on the classification and therapy of traumatic spondylolisthesis of the axis are diverse. The immunoglobulin heavy-chain binding protein (Bip)/glucose-regulated protein 78 (GRP78), calnexin, calreticulin, glucose-regulated protein 94 (GRP94)/gp96, oxygen regulated protein 150 (ORP150)/glucose-regulated protein 170 (GRP170), homocysteine-induced ER protein (Herp) and heat shock protein 47 (hsp47)/Serpin H1, which are expressed not only in the ER but also occasionally at the cell surface play pathophysiological roles in autoimmune and inflammatory diseases as pro- or anti-inflammatory factors. The authors reviewed data obtained previously for 258 patients (127 women and 131 men) anesthetized with desflurane, diethyl ether, halothane, methoxyflurane, sevoflurane, or xenon. Ventricular arrhythmias induced by sympathomimetic amines in unanesthetized dogs following coronary artery occlusion. Considering with available epidemiological information, a preliminary sanitary standard of aluminium in drinking water 0.2 mg/L is recommended. The chain of wetlands in the eastern side of the study area has been evolved from a mega lagoon existed during Late Pleistocene. PRECIPITINS IN SERA OF SWINE INFECTED WITH STEPHANURUS DENTATUS.

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In the domains assessed, these two groups have similar outcomes from surgery. Anti-inflammatory activity studies on the stems and roots of Jasminum lanceolarium Roxb. Use of the chick embryo in maintaining and restoring virulence of Neisseria gonorrhoeae. Asthma may appear in a mild form of Addison crisis in a patient with CGKD. However, modulation of the phase also involves an intensity modulation of the light, which leads to a measurement error if conventional signal processing is used. If effective, this training has the potential to not only prevent falls, but to also improve safe independent mobility and engagement in daily activities for those with stroke. The ability of K2T23 in photosensitizing the production of singlet oxygen is compared with that of curcumin. Higher nitrate levels indicative of nitrosative stress were observed in the deficient muscle compared to control muscle. In contrast, a strong (higher than C-C rate) positive relationship between rainfall extremes and dew point (DPT) and tropospheric temperature (T850) is shown for most of the stations, which was previously unexplored. How Imaging Can Impact Clinical Trial Design: Molecular Imaging as a Biomarker for Targeted Cancer Therapy.

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In COACH, a random-like coded phase mask (CPM) is used as a coded aperture. The basic residues Arg6 and Arg7 contribute to the KOR affinity and agonist potency of Dyn B amide, while Lys10 contributes to the opioid receptor affinity, but not KOR agonist potency, of this peptide. Seasonal changes in body and adrenal weights of chipmunks (Eutamias). The purpose of this study was to characterizing the CSM-related thalamocortical disturbances, which were associated with spinal cord structural injury, and clinical measures. Some indications are provided as regards preventive and interceptive orthodontics (including treatment aimed to reducing the severity of problems) in the therapy of the most frequent malocclusions in this age group. The patients were observed to void with a single straight urinary stream in a forward direction. However the measurement of plasma and urinary catecholamines, VMA and Iodine 131 MIBG (meta-iodo-benzyl-guanidine) scans are usefull in case of clinical doubt in patients with renal adenocarcinoma. The value of vestibular nerve tests for the assessment of posttraumatic states of vertigo. Factors affecting the integration of educable mentally retarded students. In this study, we investigated the magnetic orientation of Schwann cells, and of a mixture of Schwann cells and collagen, after an 8-tesla magnetic field exposure.

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Action of ganglioplegics on experimental histamine-antihistamine gastric ulcer. Mitotic chromosome loss in a radiation-sensitive strain of the yeast Saccharomyces cerevisiae. Virucidal Activity of World Health Organization-Recommended Formulations Against Enveloped Viruses, Including Zika, Ebola, and Emerging Coronaviruses. Lipolytic activity of progesterone and synthetic progestins on rat parametrial adipocytes in vitro. Some illustrative examples from Vaittiyacintamani - 800 of Yukimuni and Nayanaviti-500 of Akattiyar are presented in support of the suggestion. We have reconstructed aortic valves using autologous pericardium treated with glutaraldehyde since April 2007.

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