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Fledore (Alprazolam)
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Fledore

Fledore is used to treat anxiety and panic disorders. It belongs to a class of medications called benzodiazepines which act on the brain and nerves (central nervous system) to produce a calming effect. It works by enhancing the effects of a certain natural chemical in the body (GABA). Fledore is mostly used to treat anxiety disorders, panic disorders, and nausea due to chemotherapy. Fledore may also be indicated for the treatment of generalized anxiety disorder, as well as for the treatment of anxiety conditions with co-morbid depression. The FDA label advises that the physician should periodically reassess the usefulness of the drug.

Other names for this medication:
Alpanol, Alpradol, Alpranex, Alpraquil, Alprastan, Alprazan, Alprine, Alprocalm, Altrex, Alzolam, Alzolite, Alzonex, Aryalam, Balmusa, Benzax, Cozac, Dexolam, Paxor, Restyl, Samrox, Sanprazole, Sertakem, Tenan, Tenrid, Tensfree, Zedep, Zepro

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Retin, Wellbutrin, Precose, Glucophage, Lopid, Lexapro, Exelon, Astelin

Also known as: Alprazolam

Description

Alprazolam is used to relieve symptoms of anxiety, including anxiety caused by depression. It is also used to treat panic disorder in some patients.

Alprazolam is a benzodiazepine. Benzodiazepines belong to the group of medicines called central nervous system (CNS) depressants, which are medicines that slow down the nervous system.

This medicine is available only with your doctor's prescription.

Dosage

This section provides information on the proper use of a number of products that contain alprazolam. It may not be specific to Fledore. Please read with care.

Take this medicine only as directed by your doctor. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered. If too much of this medicine is used for a long time, it may become habit-forming (causing mental or physical dependence) or cause an overdose.

This medicine should come with a Medication Guide. Read and follow the instructions carefully. Ask your doctor if you have any questions.

Swallow the extended-release tablet or tablet whole with a full glass of water. Do not break, crush, or chew it.

If you are using the orally disintegrating tablet, make sure your hands are dry before you handle the tablet. Do not remove the tablets from the bottle until you are ready to take it. Place the tablet immediately on the top of your tongue. It should melt quickly and be swallowed with saliva.

If you are using the oral liquid, measure the dose with a marked measuring spoon, oral syringe, or medicine cup.

Do not eat grapefruit or drink grapefruit juice while you are using this medicine.

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For anxiety: For oral dosage forms (solution, tablets, or orally disintegrating tablets): Adults—At first, 0.25 to 0.5 milligram (mg) 3 times a day. Your doctor may increase your dose as needed. However, the dose is usually not more than 4 mg per day. Older adults—At first, 0.25 mg 2 or 3 times a day. Your doctor may increase your dose as needed. Children—Use and dose must be determined by your doctor. For panic disorder: For oral dosage form (extended-release tablets): Adults—At first, 0.5 to 1 milligram (mg) taken in the morning once a day. Your doctor may increase your dose as needed. However, the dose is usually not more than 10 mg per day. Older adults—At first, 0.5 mg taken in the morning once a day. Your doctor may increase your dose as needed. Children—Use and dose must be determined by your doctor. For oral dosage forms (solution, tablets, or orally disintegrating tablets): Adults—At first, 0.5 milligram (mg) 3 times a day. Your doctor may increase your dose as needed. However, the dose is usually not more than 10 mg per day. Older adults—At first, 0.25 mg 2 or 3 times a day. Your doctor may increase your dose as needed. Children—Use and dose must be determined by your doctor.

Overdose

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose of alprazolam can be fatal.

Overdose symptoms may include extreme drowsiness, confusion, muscle weakness, loss of balance or coordination, feeling light-headed, and fainting.

Storage

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

It is very important to protect the orally disintegrating tablets from moisture. Remove and throw away any cotton packaging from the medicine bottle when you first use the medicine.

Detailed Fledore XR dosage information

Side effects

The most common side effects associated with Fledore are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:

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The aim of this study was to assess the role of PET in the management of patients with primary malignant salivary gland (SG) tumor. The present data show that the instructed S-R mappings influence performance on the embedded B-task, even when they (1) have never been practiced, and (2) are irrelevant with respect to the B-task. Hypothyroidism might be related to breast cancer in post-menopausal women. The aim of this study was to establish the correlation between the residual epidermal innervation of the allodynic skin and the intensity of tactile allodynia in that area. Lumbar intervertebral disk degeneration in elite competitive swimmers: a case control study. In healthy volunteers, an anesthetic injected was confined to the muscle and induced anesthesia in the skin areas innervated by both nerves. Efforts to improve feasibility of RFA especially for inconspicuous target have to be made. Three-port technique is safe, effective, and economic but does not reduce the overall pain score and analgesia requirement. Impaired left ventricular apical rotation is associated with disease activity of psoriatic arthritis. Nevertheless, few epidemiological studies have reported the characteristics of patients with nail psoriasis.

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Overexpression of the mitotic checkpoint protein Mad2 triggers chromosome missegregation but, surprisingly, Mad2 exerts this effect through a previously unknown effect on microtubule dynamics. Vulvar PD cases from QCGC were reviewed and analyzed using the computer software Statistical Package for the Social Sciences (SPSS) 11.0. Copper nanoparticles blood flow analysis through a catheterized mild stenotic artery with a thrombosis is presented. aeruginosa utilizes a flagellum-independent form of locomotion called twitching motility, which is dependent upon the extension and retraction of type IV pili. Estimation of outcrossing rates at small-scale flowering sites of the dwarf bamboo species, Sasa cernua.

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Long-term results of tension-band laminoplasty for cervical stenotic myelopathy: a ten-year follow-up. The results showed that Cd and Zn in the unpolluted oasis soil was mainly found in the residual fractionation, however, with increasing contents of Cd and Zn in the oasis soil, the distribution of Cd and Zn changed significantly. Systems biology of neutrophil differentiation and immune response. Such research receives great respect, particularly from funding bodies, which expect innovations in healthcare to emerge from a whole team rather than a single discipline. We suggest that all patients taking orlistat are at risk of this condition, which may develop insidiously and is easily overlooked.

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However, studies recently described late cardiac adverse consequences that could potentially affect functional capacity. The entire injury thus represented a bipolar dislocation of the forearm. We compared the Mechanical Heart Valve Warfarin Initiation Protocol (Protocol group) with current practice (clinical judgment-Empirical group) for patients receiving mechanical heart valves in an observational before-and-after format. ACT implementation in Africa must therefore be accompanied by control and operational measures to maintain the efficacy of ACT and to protect patients against misuse. There was no evidence of clinical benefits from these specific CPT techniques for infants receiving outpatient care for acute wheezing episodes. Possible reasons for the conflicting results in the literature are also investigated. Repeated measures analysis was conducted to examine change in MI fidelity over time.

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Benign myoepithelioma of floor of mouth with mandibular involvement: a case report and literature review. Ultimately, genome science is likely to provide comprehensive catalogs of these elements. Many other factors may be considered risk factors, such as age, occupation, and parity. The DIADEM metric was specifically designed to capture the most critical aspects in automating neuronal reconstructions, and can function in feedback loops during algorithm development. In this study, colon cancer patients who viramune suspension cost underwent minimally invasive surgery for colon cancer experienced shorter hospital stay and operative times, which resulted in lower overall inpatient treatment cost.

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Similarly, expressions of inflammatory markers were significantly increased. Previous studies have identified an important association between DM and TB. SNPs in or near Fmo3, Sele and Selp for Ath44, and Lbp and Pkig for Ath45 were suggested for further investigation as potential candidates underlying the atherosclerosis susceptibility. Internal stenting of pancreatic duct could not reduce pancreatic fistula rate after pancreaticoduodenectomy. After controlling for important factors, PM2.5 was associated with a small decrease in forced vital capacity and forced expiratory flow in one second. This study provides insight into information sources consulted and factors dictating treatment decision-making in young prostate cancer patients. We hypothesized that at the site of disease DCs are mature, immunocompetent and involved in granuloma formation. Extended high cutoff on-line hemodiafiltration is superior to extended high cutoff hemodialysis in removal of free light chain immunoglobulin of myeloma cast nephropathy. Comparison of myogenic differentiation ability of adipose-derived stem cells from different sites in rabbit. The study documents strong support for screening and intervention programs by both trauma surgeons and legislators.

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The effect of musical function was decreased, but not qualitatively changed, by chord repetition. Eighteen days later, the patient continued to demonstrate elevated CK levels (527 IU/L) but described no other symptoms and was allowed to return to football practice as tolerated. A mean doubling time of approximately 4.9 h was estimated for the 28-fold increase in P. Urban seismology has become an active research field in the recent years, both with seismological objectives, as obtaining better microzonation maps in highly populated areas, and with engineering objectives, as the monitoring of traffic or the surveying of historical buildings. Genome-wide identification of Streptococcus pneumoniae genes essential for bacterial replication during experimental meningitis. At any age, the claim rates decline as time on the job increases. The array, which contains 200 carbohydrates and glycoproteins, not only revealed clear differentiation of receptor preferences for alpha2-3 and/or alpha2-6 sialic acid linkage, but could also detect fine differences in HA specificity, such as preferences for fucosylation, sulfation and sialylation at positions 2 (Gal) and 3 (GlcNAc, GalNAc) of the terminal trisaccharide. The identification and analysis of limiting factors for high internal quantum efficiencies (IQE) are accomplished through the current injection efficiency model. It was concluded that whereas alcohol slows attention allocation and impairs working memory, caffeine accelerated response-related decisions and enhanced cortical arousal.

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We study the Turing bifurcation in general two-species reaction-transport systems, where particle dispersal is governed by diffusion, including cross diffusion. Cholinergic interneurons of the striatum respond to motivationally relevant stimuli and are involved in appetitive learning. Data are presented demonstrating that inappropriate reference gene selection can have profound influence on study conclusions ranging from divergent statistical outcome to inaccurate data interpretation of significant magnitude. Pathogenesis of functional dyspepsia (FD) is unclear and not well documented. Most of these studies obtained PRP using different separation systems, and few analyzed the content of the PRP used as treatment. However, it is not superior to manual phacoemulsification in terms of primary outcomes such as visual and refractive outcomes or overall complications. QoL was measured with the use of EORTC QLQ-C30 and QLQ-BR23 questionnaires.

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