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Nexium (Esomeprazole)

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Nexium is used to treat gastroesophageal reflux disease (GERD), ulcers, certain bacteria in the stomach, and inflammation of the esophagus. It can also be used to prevent ulcers in patients taking medicines called NSAIDs. Nexium is more popular than other proton pump inhibitors. It is available in brand and generic versions.

Other names for this medication:
Epraz, Esgred, Esodoc, Esofag, Esofine, Esomac, Esomeprazole, Esomper, Esoper, Esotrax, Ignis, Naksium, Neutraflux, Nexpro, Prazonid, Raciper, Ranidom, Sompraz

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Also known as: Esomeprazole


Esomeprazole injection is used to treat conditions where there is too much acid in the stomach. It is used for the short-term treatment (up to 10 days) of gastroesophageal reflux disease (GERD) with erosive esophagitis in adults and children 1 month of age and older. GERD is a condition where the acid in the stomach washes back up into the esophagus. This medicine is also used to lower the risk of rebleeding in patients with acute gastric or duodenal ulcer after endoscopy.

Esomeprazole is a proton pump inhibitor (PPI). It works by decreasing the amount of acid that is produced by the stomach.

This medicine is to be given only by or under the direct supervision of your doctor.


Take Generic Nexium orally at the same time every day. Do not chew or crush the delayed-release capsule. If you use Generic Nexium in the treatment of GERD you should take it for 4-8 weeks. If you use Generic Nexium in the treatment of gastric ulcer you can take it together with other medicines for 10 days. Take Generic Nexium once a day, one hour before a meal. If you want to achieve most effective results do not stop taking Generic Nexium suddenly.


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.


Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Detailed Nexium dosage information

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The most common side effects associated with Nexium are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


You should not use Nexium if you are allergic to esomeprazole or to similar medicines such as lansoprazole (Prevacid), omeprazole (Prilosec, Zegerid), pantoprazole (Protonix), or rabeprazole (AcipHex).

Heartburn can mimic early symptoms of a heart attack. Get emergency medical help if you have chest pain that spreads to your jaw or shoulder and you feel anxious or light-headed.

You should not use this medicine if you have had breathing or kidney problems.

Tell your doctor if you have ever had:

severe liver disease; lupus; osteoporosis or low bone mineral density (osteopenia); or low levels of magnesium in your blood.

You may be more likely to have a broken bone in your hip, wrist, or spine while taking a proton pump inhibitor long-term or more than once per day. Talk with your doctor about ways to keep your bones healthy.

Ask a doctor before using this medicine if you are pregnant or breastfeeding.

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