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Osteobel (Calcitriol)
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Osteobel

Osteobel is a synthetic physiologically-active analog of vitamin D, specifically the vitamin D3 form. Osteobel regulates calcium in vivo by promoting absorption in the intestine, reabsorption in the kidneys, and, along with parathyroid hormone, regulation of bone growth. Osteobel receptor-binding protein appears to exist in the mucosa of human intestine.

Other names for this medication:
Alfacip, Bonestat, Calasto, Calbec, Calbory, Calbovic, Calcicare, Calcimet, Calcitriol, Caldix, Calfa, Calsonic, Calsure, Caltin, Calvical, Coecoral, Devita, Duracal, Ikmag, Koncal, Kurecal, Netxod, Novadee, Ostriol, Politrol, Rical, Riecal, Ritoca, Sorvate, Trolec

Similar Products:
Artane, Cardizem, Maxalt, Tofranil, Zyrtec, Viramune

Also known as: Calcitriol

Description

Generic Osteobel is a synthetic vitamin D analog which is active in the regulation of the absorption of calcium from the gastrointestinal tract and its utilization in the body. The two known sites of action of Generic Osteobel are intestine and bone. Generic Osteobel receptor-binding protein appears to exist in the mucosa of human intestine. Additional evidence suggests that Generic Osteobel may also act on the kidney and the parathyroid glands. Generic Osteobel is the most active known form of vitamin D3 in stimulating intestinal calcium transport. In acutely uremic rats Generic Osteobel has been shown to stimulate intestinal calcium absorption. The kidneys of uremic patients cannot adequately synthesize Generic Osteobel, the active hormone formed from precursor vitamin D. Resultant hypocalcemia and secondary hyperparathyroidism are a major cause of the metabolic bone disease of renal failure. However, other bone-toxic substances which accumulate in uremia (eg, aluminum) may also contribute. The beneficial effect of Generic Osteobel in renal osteodystrophy appears to result from correction of hypocalcemia and secondary hyperparathyroidism. It is uncertain whether Generic Osteobel produces other independent beneficial effects. Osteobel is also known as Calcitriol. Generic Osteobel treatment is not associated with an accelerated rate of renal function deterioration. No radiographic evidence of extraskeletal calcification has been found in predialysis patients following treatment. The duration of pharmacologic activity of a single dose of calcitriol is about 3 to 5 days. Generic name of Generic Osteobel is Calcitriol. Brand name of Generic Osteobel is Osteobel.

Dosage

Generic Osteobel is available in capsules (0.25 mcg) and liquid form. Capsules must be swallowed whole. Do not crush or chew them. If you are prescribed the liquid form, use as directed. Follow dosing instructions closely. Do not take this medication with mineral oil or magnesium containing antacids which may reduce its effects. Foods rich in vitamin D include: fortified dairy products, eggs, sardines, cod liver oil, chicken livers and fresh-water fish. Vitamin D is also obtained from periodic exposure to the sun. It is important to maintain a well-balanced diet while taking this medication. Calcium supplements may be recommended in addition to this medication. If you want to achieve most effective results do not stop taking Generic Osteobel suddenly.

Overdose

If you overdose Generic Osteobel and you don't feel good you should visit your doctor or health care provider immediately.

Storage

Keep out of the reach of children.

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Do not keep outdated medicine or medicine no longer needed.

Side effects

The most common side effects associated with Osteobel are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Do not take Generic Osteobel if you are allergic to Generic Osteobel components. Do not take Generic Osteobel if you are pregnant, planning to become pregnant, or are breast-feeding. It is not known if this medication appears in breast milk. Do not take this medication with mineral oil or magnesium containing antacids which may reduce its effects. Be careful with Generic Osteobel if you have heart disease, kidney disease or kidney stones, coronary artery disease (hardening of the arteries). Foods rich in vitamin D include: fortified dairy products, eggs, sardines, cod liver oil, chicken livers and fresh-water fish. Vitamin D is also obtained from periodic exposure to the sun. It is important to maintain a well-balanced diet while taking this medication. Calcium supplements may be recommended in addition to this medication. It can be dangerous to stop Generic Osteobel taking suddenly.

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Management practices to support donor transition: lessons from Avahan, the India AIDS Initiative. We compared the image quality of low-mAs head CT scans with that of conventional nonenhanced scans. It is concluded that the mechanical stimulation and/or trauma involved in the implantation of a cannula in the LC is sufficient to cause widespread activation of noradrenergic neurotransmission throughout the forebrain. The contrast-enhanced abdominal computed tomography (CT) showed intestinal obstruction at the third-portion of the duodenum. French fries and potato chips contribute a significant proportion to the average daily intake of acrylamide, especially in developed countries.

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Clinical results of aphakia correction with bifocal intraocular lenses. Consequences of retinal image clarity versus occlusion (absent) versus diffusion. We summarized the results of previous genomic and functional studies of pro-BDNF and mature-BDNF (m-BDNF) found in a literature review. The prediction of the in vivo drug release characteristics of modified release (MR) oral dosage forms by in vitro dissolution tests is does imodium work with antibiotics a prerequisite for successful product development. This property was exploited to purify a representative ESK produced by Streptococcus equisimilis strain 87-542-W. A relative value method for measuring and evaluating neonatal cardiac reserve. Even though young women have achieved gains in earnings, employment, and schooling relative to men in recent decades, those without a college degree also struggle to achieve economic stability and self-sufficiency. Transcriptional repression at these sites depends on the silent information regulators SIR3 and SIR4 as well as histones H3 and H4.

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Gender difference in adiponectin associated with cardiovascular mortality. The study objective is to develop and validate an zyvox 600mg tablet price electronic surveillance tool (AKI sniffer) to detect AKI in 2 independent retrospective cohorts of intensive care unit (ICU) patients. Surgical treatment of umbilical hernias in adults, presentation technique, previous note. Self-reported measures of anhedonia, approach and avoidance motivation were completed by the Sydney sample. Effects of KCNQ1 channel blocker, 293B, on the acetylcholine-induced Cl- secretion of rat pancreatic acini. Fetal blood sampling in prenatal diagnosis of thalassemia at late pregnancy. Experimental studies have shown that IL-2 may antagonize chemotherapy-induced lymphocytopenia.

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Seizures and dementia in the elderly: Nationwide Inpatient Sample 1999-2008. We selected 400 nuclear families from the data generated for Problem 2. Experimental and Theoretical Investigations on Structural and Vibrational Properties of Melilite-Type Sr2ZnGe2O7 at High Pressure and Delineation of a High-Pressure Monoclinic Phase. The chemical composition and submicroscopic morphology of Mycoplasma gallisepticum, avian PPLO 5969. Novel endogenous dipeptide cycloprolyl-glycine is similar to pyracetam in selectivity of their mnemotropic effect. Bio-nanomuscle project: contractile properties of single actin filaments in an A-band motility assay system.

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Since FGF21 is believed to exert its effects mostly at the transcriptional level, we analyzed and observed significant upregulation in expression of various genes involved in carbohydrate and lipid metabolism, energy homeostasis, and antioxidant defense in FGF21-treated controls, but not in GH transgenics. While normal laboratory mice are resistant to LASV, we report that mice expressing humanized instead of murine MHC class I (MHC-I) failed to control LASV infection and develop severe LF. Arenaviruses are feared as agents that cause viral hemorrhagic fevers. These models illustrate the potential for this approach to reveal relationships within richly structured data that may not be apparent using conventional statistical approaches. Human plasma cells were detected in the mesenteric fat tissue around the pancreas and the spleen. In media of pH 3 and 9, cadmium did not affect the dry mass content substantially.

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We showed that in long-tern cultures (48 h) of K562 cells with AG-490 or WHI-P132 the cells remain viable. Dengue is currently the most important arthropod-borne viral disease of humans. Efficacy and absence of toxicity of cystamine, by ingestion, in the rat. The aim of the present work was to test whether cerebral vasomotor-reactivity is impaired in patients with SAE. In the present study, we used the immunofluorescence staining technique to demonstrate the presence of c-Src, a member of Src family PTK, in the thick ascending limb (TAL) and collecting duct. This review presents substantial data gathered across multiple, divergent metazoan genomes to unambiguously trace the origin of these genes. It usually functions as a transcriptional co-activator by associating with H3K4me3 and RNA polymerase II. Twelve trials were identified from the search as being relevant to the review. We have later passage MCF-7 breast cancer cell lines with elevated, constitutive expression of hsp27 mRNA, perhaps due to hsp27 gene amplification.

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Heterozygous not3 knockout mice showed spontaneous impairment of cardiac contractility and increased susceptibility to heart failure. The best model of original spectra at 0 mm distance yielded high correlation de-termination of 0.918, a SEC of 0.092, and a SEP of 0.773. Symptomatic members had a battery of tests, including electrophysiologic studies, ambulatory ECGs, audiograms, exercise stress testing, serum catecholamine levels during rest and exercise and isoproterenol infusion. Full-length ADP, mutant ADP with Cys39 replaced with serine, and globular ADP were effective, whereas the collagenous tail fragment was not. The two groups were compared in terms of the baseline clinicoradiologic characteristics and outcomes, including the image stability, image-detected breast cancer and the cancer stage at detection. A second aim was to elaborate on the implications of these findings for the development of quality management strategies. Patients were monitored by clinical and laboratory evaluations for therapeutic efficacy and adverse events during the acute treatment phase and for 8 weeks after therapy was discontinued. Histochemical demonstration of carbonic anhydrase in the larynx.

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