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Singulair

Singulair is in a class of medications called leukotriene receptor antagonists (LTRAs). It works by blocking the action of substances in the body that cause the symptoms of asthma and allergic rhinitis.

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Also known as: Montelukast

Description

Target of Singulair is to treat symptoms of asthma, perennial and seasonal allergic rhinitis. Sometimes Singulair is taken to prevent exercise-induced bronchoconstriction in patients who take this medicine only for this condition.This remedy works by obstructing the activity of substances which cause symptoms of allergy and asthma. It is LTRA (leukotriene receptor antagonist). Singulair is also known as Montelukast sodium, Montair, Montus, Romilast.

Dosage

Asthma: - Adults (15 years of age and older): 10 mg a day. - Children (6 to 14 years of age): 5 mg a day. - Children (2 to 5 years of age): 4 mg a day. Singulair should be taken once a day in the evening. Exercise-Induced Bronchoconstriction (EIB): - Adults (15 years of age and older): 10 mg a day. - Children (6 to 14 years of age): 5 mg a day. - Children (2 to 5 years of age): 4 mg a day. For prevention of EIB, Singulair should be taken at least 2 hours before exercise. Do not take more than one dose in 24 hours. Allergic Rhinitis: - Adults (15 years of age and older): 10 mg a day. - Children (6 to 14 years of age): 5 mg a day. - Children (2 to 5 years of age): 4 mg a day. For allergic rhinitis, Singulair should be taken once a day. Patients with both asthma and allergic rhinitis should take only one Singulair dose daily in the evening. Pediatric patients are advised to take chewable tablets.

Overdose

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Storage

Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) away from moisture, light and heat. Keep this medicine in the original bottle. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Singulair are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Do not take Singulair if you are allergic to its components or to aspirin. Do not take Singulair if you use Singulair while you are pregnant or have nurseling. You should not use Singulair for exercise-induced bronchoconstriction if you already take Singulair to prevent symptoms of allergy or asthma. Try to be careful using Singulair if you take phenobarbital (such as Solfoton, Luminal), rifampin (such as Rifamate, Rifadin, Rimactane, Rifater). It can be dangerous to use Singulair if you suffer from or have a history of phenylketonuria, liver disease. Avoid any activities such as driving or operating machinery while taking Singulair. It can be dangerous to stop Singulair taking suddenly.

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An acute lethal myopericarditis has been observed in four out of fifteen patients receiving high-dose combination chemotherapy which includes cyclophosphamide 45 mg/kg/day for four days. Our aim was to compare fatigue and depression in prostate cancer patients treated with Androgen Deprivation Therapy (ADT) and in patients with Lower Urinary Tract Symptoms (LUTS) / Benign Prostatic Syndrome. Other reasons excluded, sclerosing peritonitis was attributed to the formalin solution employed as disinfectant for the abdominal catheter. Using simulated and empirical data, we find that the approach of using observed prey proportions consistently overestimates diet specialization relative to the Bayesian hierarchical approach when the number of prey observations per individual is low or the number of prey observations vary among individuals, two common features of empirical data. Family support and self-concept moderated the influence of life stress and cumulative risk on problem behavior outcomes, but these protective variables did not significantly moderate violence exposure. Particle irradiation started to draw attention in the past decade and has now become a hotspot in the radiation oncology community.

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Correspondences between biomathematical and causal models for clinical decision making. Other measured nutrients as DHA, all analysed vitamins, manganese, copper and selenium were similar or higher in the rotifers. INtimal hyPerplasia evAluated by oCT in de novo COROnary lesions treated by drug-eluting balloon and bare-metal stent (IN-PACT CORO): study protocol for a randomized controlled trial. Additional evidence as to the persistence of axonal debris in degenerated optic nerves was obtained by electron microscopy. Nitrotyrosine Density of Rabbit Urinary Bladder Muscle and Mucosa Measured via Western Blotting and 96-Well Plate Analysis. To address this knowledge gap, we collaborated with eight secondary schools to conduct a survey of movement patterns of school pupils in primary and secondary schools in the United Kingdom. The negative short-loop feedback of LH inhibits basal LHRH release in vitro since antiserum against LH increased LHRH release. CONSIDERATIONS ON THE TREATMENT OF SUBARACHNOID HEMORRHAGE WITH CORTISONE-LIKE AGENTS. Microbial DNA records historical delivery of anthropogenic mercury.

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Fundus findings in a series of patients with extrapulmonary tuberculosis in Thailand. Cardiac effects of histamine include stimulation of sinus rate and ventricular contractile force, impairment of atrioventricular conduction and increase in ventricular automaticity. A key observation is that the saliency of a superpixel can be estimated by the distance from the most certain foreground and background seeds. A Cochrane systematic review examining 11 non-randomized and 1 randomized study showed laparoscopic surgery to be feasible in diverticular disease, although there might be a higher minor complications rate in laparoscopic resections. Production of L-lactic acid from metabolically engineered strain of Enterobacter aerogenes ATCC 29007. The use of NaNO3 in the mixture with glucose eliminated inhibition and increased the ratio of ATP to ADP and the antibiotic yield. A method is proposed for using Staphylococcus aureus containing protein A for the detection and measurement of insulin antibodies in the sera of insulin-requiring diabetics. Immunoreactivity to each isoform of NOS was immunohistochemically observed. A device for functional residual capacity controlled biofeedback of respiratory resistance.

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Designing Fit for Purpose Health and Social Services for Ageing Populations. Augmented nitric oxide production and up-regulation of endothelial nitric oxide synthase during cecal ligation and perforation. Proceedings: An appraisal of EEG in relation to clinical psychology. The membrane-bound peptidases aminopeptidase A (APA), aminopeptidase M (APM), gamma-glutamyl-transferase (gamma-GT), dipeptidylpeptidase IV (DAP IV), and the lysosomal dipeptidyl peptidases I (DAP I) and II (DAP II) were investigated in male and female (estrus) rats both before and 30 days after castration. A resource for the conditional ablation of microRNAs in the mouse. Pulmonary arterial pressures were measured during routine respiratory mechanics measurements throughout ARDS.

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