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Singulair (Montelukast)

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Singulair is in a class of medications called leukotriene receptor antagonists (LTRAs). It works by blocking the action of substances in the body that cause the symptoms of asthma and allergic rhinitis.

Other names for this medication:
Adomont, Airmont, Almont, Alzero, Ancer, Briocold, Centiluk, Deriphyllin, Histakind, Irmont, Jotair, Letzit, Levasma, Levodel, Lupimon, Moncy, Montasma, Montelast, Montemac, Montolife, Montral, Nexofex, Rivoce, Tykast, Ventyl

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Also known as: Montelukast


Target of Singulair is to treat symptoms of asthma, perennial and seasonal allergic rhinitis. Sometimes Singulair is taken to prevent exercise-induced bronchoconstriction in patients who take this medicine only for this condition.This remedy works by obstructing the activity of substances which cause symptoms of allergy and asthma. It is LTRA (leukotriene receptor antagonist). Singulair is also known as Montelukast sodium, Montair, Montus, Romilast.


Asthma: - Adults (15 years of age and older): 10 mg a day. - Children (6 to 14 years of age): 5 mg a day. - Children (2 to 5 years of age): 4 mg a day. Singulair should be taken once a day in the evening. Exercise-Induced Bronchoconstriction (EIB): - Adults (15 years of age and older): 10 mg a day. - Children (6 to 14 years of age): 5 mg a day. - Children (2 to 5 years of age): 4 mg a day. For prevention of EIB, Singulair should be taken at least 2 hours before exercise. Do not take more than one dose in 24 hours. Allergic Rhinitis: - Adults (15 years of age and older): 10 mg a day. - Children (6 to 14 years of age): 5 mg a day. - Children (2 to 5 years of age): 4 mg a day. For allergic rhinitis, Singulair should be taken once a day. Patients with both asthma and allergic rhinitis should take only one Singulair dose daily in the evening. Pediatric patients are advised to take chewable tablets.


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.


Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) away from moisture, light and heat. Keep this medicine in the original bottle. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Singulair are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Do not take Singulair if you are allergic to its components or to aspirin. Do not take Singulair if you use Singulair while you are pregnant or have nurseling. You should not use Singulair for exercise-induced bronchoconstriction if you already take Singulair to prevent symptoms of allergy or asthma. Try to be careful using Singulair if you take phenobarbital (such as Solfoton, Luminal), rifampin (such as Rifamate, Rifadin, Rimactane, Rifater). It can be dangerous to use Singulair if you suffer from or have a history of phenylketonuria, liver disease. Avoid any activities such as driving or operating machinery while taking Singulair. It can be dangerous to stop Singulair taking suddenly.

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Adrenal demedullation completely prevented the hyperglycemia, but did not affect the hyperthermic effect of PGF2 alpha. The present study was carried out to determine if the reticuloendothelial system (RES) depression induced by the injection of hemolyzed blood and components of hemolyzed blood was associated with an increase in susceptibility to endotoxin shock and thermal injury. delicatissima, thus resulting in short-term species displacement and extinction by hybridization and recurrent introgression from I. N-2 language repetition costs denote worse performance when switching back to a recently abandoned language (i.e., worse performance in ABA language sequences than CBA sequences, where A, B, and C refer to different languages). Colon transit time (CTT) is a useful diagnostic tool in chronic constipation, but requires good patient compliance.

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Moreover, this effect of environmental variation could be markedly alleviated when the sample size was higher than 450, and thus we predicted that there were at least 42,866 soil bacterial species based on 8,296,878 sequences from 550 samples in the whole 50 ha FDP. The chromatin template activity of the polytene chromosomes in larval salivary glands of Drosophila hydei has been assayed by in situ transcription, on the fixed chromatin using E. The serine derivative shows a much greater tendency to undergo these side-reactions than the threonine derivative. The geometric standard deviations between the correlation predictions and the measurements are 1.98 for the diffusion coefficients and 2.31 for the soil air permeabilities. The PUF system works very well for aromatic as well as non-aromatic compounds, whereas the denuder shows smaller collection efficiencies for highly volatile non-aromatic compounds. The presence of UPF1 in these subcellular compartments was increased by Tax, whereas that of INT6 was decreased. The frequency-following response in subjects with profound unilateral hearing loss. Dopamine (DA) D4 receptors have been implicated in schizophrenia and the ability of some atypical antipsychotic drugs (APDs) to improve the cognitive impairment associated with schizophrenia (CIAS).

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Variables that influenced correlation included history of previous surgeries, type of anesthetic used, interpretation criteria, and whether the patient was awake or asleep. Our study reveals that attitudes toward health check-ups and perceived barriers to mammographic screening were influential in determining compliance with breast cancer screening practices among Indian-Australian women. The magnitude of this decrease in BP is related to the rate of gastric emptying (GE). Endovascular options are commonly being used in young patients, especially those with claudication, but patency rates and outcomes remain very poor. The latter then activates IL-1R-associated kinases that in turn recruit well-characterised downstream effectors culminating in activation of MAP kinases and transcription factors such as NFkappaB and AP-1. G3 product was purified using affinity columns, and the purified G3 also enhanced cell adhesion.

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An acute lethal myopericarditis has been observed in four out of fifteen patients receiving high-dose combination chemotherapy which includes cyclophosphamide 45 mg/kg/day for four days. Our aim was to compare fatigue and depression in prostate cancer patients treated with Androgen Deprivation Therapy (ADT) and in patients with Lower Urinary Tract Symptoms (LUTS) / Benign Prostatic Syndrome. Other reasons excluded, sclerosing peritonitis was attributed to the formalin solution employed as disinfectant for the abdominal catheter. Using simulated and empirical data, we find that the approach of using observed prey proportions consistently overestimates diet specialization relative to the Bayesian hierarchical approach when the number of prey observations per individual is low or the number of prey observations vary among individuals, two common features of empirical data. Family support and self-concept moderated the influence of life stress and cumulative risk on problem behavior outcomes, but these protective variables did not significantly moderate violence exposure. Particle irradiation started to draw attention in the past decade and has now become a hotspot in the radiation oncology community.

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Study protocol of the German Study on Tobacco Use (DEBRA): a national household survey of smoking behaviour and cessation. The purpose of the present study was to examine the interactions among the laryngeal cancer cells and fibrinolytic system components in loco. Our findings suggest that BEZ235 may be an effective agent for the treatment of MCL. The sequence of the A238L gene homologue to the cellular IkappaB was found identical in both viral isolates and its expression at mRNA level was higher in macrophages infected with NHV when compared to macrophages infected with L60. Structural lasix 40 mg tablet uses in hindi insight into allosteric modulation of protease-activated receptor 2. At a dose that eliminated the locomotor depressant effect of clonidine, the alpha 2 -antagonist yohimbine did not antagonize the locomotor stimulant effects of phenylephrine and methoxamine. Demanding conditions as well as interruptions revealed rapid forgetting of intentions at levels that would be considered significant in applied settings. Indications and importance of biliary-digestive tract anastomosis in the treatment of cholelithiasis.

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The conjugative plasmid pWBG637 was able to mobilise a further 4.4-kb plasmid (pWBG633) encoding streptomycin resistance and recombined with the multiresistance plasmid pWBG628 to produce transconjugantes of various resistance phenotypes. An additional 8 survey items inquired about the sources from which people obtained their knowledge, extent of personal experience with brain injury, occupational status, educational status, residential status, and their use of seatbelts. Out of the desk and onto the stage: an experiment in assertive role playing. Multivariate regression modeling was conducted to identify factors independently associated with a favorable outcome. Metachronous muscle metastases as a unique manifestation of colon cancer relapse. The National Heart, Lung, and Blood Institute (NHLBI) convened a workshop in March 2016 to review the state of preclinical science addressing the three most important complications of lung transplantation: primary graft dysfunction (PGD), acute rejection (AR), and chronic lung allograft dysfunction (CLAD). We have recently shown that CCK in man and pig circulates in low concentrations (a few pmol) making blood-borne CCK an unlikely satiety signal. The choice of drugs suggests that many suicidal people deliberately take anxiety-and tension-reducing agents, a fact which points to a relationship between anxiety states and attempted suicide.

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In a group of 69 patients with chronic renal failure, 18 patients after renal transplantation and 8 healthy controls the influence of inorganic phosphate and pH of plasma and of the hemoglobin concentration in whole blood on the 2,3-DPG concentration in red blood cells was investigated. With low dose HRT in a continuous combined regimen amenorrhoea will be obtained in a majority of women after a few months of treatment. Our analyses revealed that SPF45 is expressed in many, but not all, normal tissues tested with predominant expression in normal ductal epithelial cells of the breast, liver, pancreas, and prostate. Immunohistochemical study on the distribution plavix and alcohol of alpha and beta subunits of S-100 protein in brain tumors. Is the induction of tumor cell senescence the key to a good irradiated tumor vaccine?.

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Correspondences between biomathematical and causal models for clinical decision making. Other measured nutrients as DHA, all analysed vitamins, manganese, copper and selenium were similar or higher in the rotifers. INtimal hyPerplasia evAluated by oCT in de novo COROnary lesions treated by drug-eluting balloon and bare-metal stent (IN-PACT CORO): study protocol for a randomized controlled trial. Additional evidence as to the persistence of axonal debris in degenerated optic nerves was obtained by electron microscopy. Nitrotyrosine Density of Rabbit Urinary Bladder Muscle and Mucosa Measured via Western Blotting and 96-Well Plate Analysis. To address this knowledge gap, we collaborated with eight secondary schools to conduct a survey of movement patterns of school pupils in primary and secondary schools in the United Kingdom. The negative short-loop feedback of LH inhibits basal LHRH release in vitro since antiserum against LH increased LHRH release. CONSIDERATIONS ON THE TREATMENT OF SUBARACHNOID HEMORRHAGE WITH CORTISONE-LIKE AGENTS. Microbial DNA records historical delivery of anthropogenic mercury.

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Fundus findings in a series of patients with extrapulmonary tuberculosis in Thailand. Cardiac effects of histamine include stimulation of sinus rate and ventricular contractile force, impairment of atrioventricular conduction and increase in ventricular automaticity. A key observation is that the saliency of a superpixel can be estimated by the distance from the most certain foreground and background seeds. A Cochrane systematic review examining 11 non-randomized and 1 randomized study showed laparoscopic surgery to be feasible in diverticular disease, although there might be a higher minor complications rate in laparoscopic resections. Production of L-lactic acid from metabolically engineered strain of Enterobacter aerogenes ATCC 29007. The use of NaNO3 in the mixture with glucose eliminated inhibition and increased the ratio of ATP to ADP and the antibiotic yield. A method is proposed for using Staphylococcus aureus containing protein A for the detection and measurement of insulin antibodies in the sera of insulin-requiring diabetics. Immunoreactivity to each isoform of NOS was immunohistochemically observed. A device for functional residual capacity controlled biofeedback of respiratory resistance.

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Designing Fit for Purpose Health and Social Services for Ageing Populations. Augmented nitric oxide production and up-regulation of endothelial nitric oxide synthase during cecal ligation and perforation. Proceedings: An appraisal of EEG in relation to clinical psychology. The membrane-bound peptidases aminopeptidase A (APA), aminopeptidase M (APM), gamma-glutamyl-transferase (gamma-GT), dipeptidylpeptidase IV (DAP IV), and the lysosomal dipeptidyl peptidases I (DAP I) and II (DAP II) were investigated in male and female (estrus) rats both before and 30 days after castration. A resource for the conditional ablation of microRNAs in the mouse. Pulmonary arterial pressures were measured during routine respiratory mechanics measurements throughout ARDS.

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